Gene Symbol | SUSD2 |
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Entrez Gene | 56241 |
Alt Symbol | BK65A6.2 |
Species | Human |
Gene Type | protein-coding |
Description | sushi domain containing 2 |
Other Description | Sushi domain (SCR repeat) containing|sushi domain-containing protein 2 |
Swissprots | Q9UGT4 Q9H5Y6 |
Accessions | CAB62953 EAW59641 EAW59642 Q9UGT4 AK026431 BAB15481 AK126105 BC033107 AAH33107 BI822588 NM_019601 NP_062547 |
Function | May be a cytokine receptor for C10ORF99. May be a tumor suppressor; together with C10ORF99 has a growth inhibitory effect on colon cancer cells which includes G1 cell cycle arrest (PubMed:25351403). May play a role in breast tumorigenesis (PubMed:23131994). {ECO:0000269|PubMed:23131994, ECO:0000269|PubMed:25351403}. |
Subcellular Location | Cell membrane {ECO:0000269|PubMed:23131994, ECO:0000269|PubMed:25351403}; Single-pass type I membrane protein {ECO:0000305}. Note=SUSD2 and LGALS1 co-localized in very specific, punctate regions along the cell membrane of breast cancer cells. {ECO:0000269|PubMed:23131994}. |
Tissue Specificity | Highly expressed in breast cancer, but shows a restricted expression pattern in normal tissues such as adipose, adrenal gland, kidney, lung, mammary gland, placenta, thyroid, trachea, and uterus (PubMed:23131994). Also expressed in colon; down-regulated in colon cancer tisues (PubMed:25351403). {ECO:0000269|PubMed:23131994, ECO:0000269|PubMed:25351403}. |
Human SUSD2 full length protein - ab163362 from Abcam
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SUSD2 Antibody Blocking Peptide - LS-E2145 from LifeSpan Bioscience
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SUSD2 Antibody Blocking Peptide - LS-E29419 from LifeSpan Bioscience
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SUSD2 Antibody Blocking Peptide - LS-E29421 from LifeSpan Bioscience
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SUSD2 Antibody Blocking Peptide - LS-E29422 from LifeSpan Bioscience
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Recombinant Human SUSD2 Protein - H00056241-P01 from Novus Biologicals
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SUSD2-Antibody-C-term-Blocking-peptide - BP13050b from Abgent, a WuXi AppTec company
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SUSD2 - H00056241-P01-10 from Acris Antibodies
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SUSD2 - H00056241-P01-25 from Acris Antibodies
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Recombinant Human Sushi domain-containing protein 2(SUSD2) - CSB-YP866225HU CSB-EP866225HU CSB-BP866225HU CSB-MP866225HU from Cusabio
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SUSD2 Recombinant Protein Antigen - NBP1-88589PEP from Novus Biologicals
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SUSD2 Peptide, Human - M34GP15424H from Creative Peptides
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Sushi domain-containing protein 2 (SUSD2), Recombinant Protein - MBS1435158 from MyBioSource
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