Gene Symbol | SPON2 |
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Entrez Gene | 10417 |
Alt Symbol | DIL-1, DIL1, M-SPONDIN, MINDIN |
Species | Human |
Gene Type | protein-coding |
Description | spondin 2, extracellular matrix protein |
Other Description | differentially expressed in cancerous and non-cancerous lung cells 1|spondin-2 |
Swissprots | Q9ULW1 Q9BUD6 Q4W5N4 D3DVN9 |
Accessions | AAY40988 CAF85941 EAW82604 EAW82605 EAW82606 Q9BUD6 AA864573 AB027466 BAA85892 AK024499 BAB15789 AK026054 AK074618 BAC11092 AK074770 BAC11196 AK130164 AY358948 AAQ89307 BC002707 AAH02707 BC036341 AAH36341 BC086866 BY797606 CB104725 DA087369 DA092888 DA201089 DA375259 DB249869 DB254983 NM_001128325 NP_001121797 NM_001199021 NP_001185950 NM_012445 NP_036577 |
Function | Cell adhesion protein that promotes adhesion and outgrowth of hippocampal embryonic neurons. Binds directly to bacteria and their components and functions as an opsonin for macrophage phagocytosis of bacteria. Essential in the initiation of the innate immune response and represents a unique pattern- recognition molecule in the ECM for microbial pathogens (By similarity). Binds bacterial lipopolysaccharide (LPS). {ECO:0000250}. |
Subcellular Location | Secreted, extracellular space, extracellular matrix {ECO:0000250}. |
Tissue Specificity | Expressed in normal lung tissue but not in lung carcinoma cell lines. {ECO:0000269|PubMed:10512675}. |
Mindin (D-4) - sc-376562 from Santa Cruz Biotechnology
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Mindin (H-131) - sc-98927 from Santa Cruz Biotechnology
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Mindin (A-9) - sc-166867 from Santa Cruz Biotechnology
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Mindin (A-10) - sc-166868 from Santa Cruz Biotechnology
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Mindin (C-17) - sc-49049 from Santa Cruz Biotechnology
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Mindin (N-13) - sc-49050 from Santa Cruz Biotechnology
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Mindin (W-18) - sc-49052 from Santa Cruz Biotechnology
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Anti-SPON2 antibody - ab130133 from Abcam
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Anti-SPON2 antibody - ab103899 from Abcam
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Anti-SPON2 antibody - ab187920 from Abcam
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Anti-SPON2 antibody - ab87254 from Abcam
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Anti-SPON2 antibody - ab138295 from Abcam
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Anti-SPON2 antibody - ab70508 from Abcam
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Anti-SPON2 antibody [EPR9799] - ab171955 from Abcam
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Anti-SPON2 / MINDIN Antibody (Trp104) - LS-C193256 from LifeSpan Bioscience
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Anti-SPON2 / MINDIN Antibody (aa119-331, Biotin) - LS-C298052 from LifeSpan Bioscience
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Anti-SPON2 / MINDIN Antibody (aa119-330, Biotin) - LS-C301017 from LifeSpan Bioscience
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Anti-SPON2 / MINDIN Antibody (aa119-331, FITC) - LS-C301831 from LifeSpan Bioscience
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Anti-SPON2 / MINDIN Antibody (aa119-330, FITC) - LS-C303545 from LifeSpan Bioscience
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Anti-SPON2 / MINDIN Antibody (aa35-84) - LS-C102421 from LifeSpan Bioscience
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Anti-SPON2 / MINDIN Antibody (aa190-239) - LS-C81713 from LifeSpan Bioscience
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Anti-SPON2 / MINDIN Antibody (aa119-331) - LS-C296490 from LifeSpan Bioscience
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Anti-SPON2 / MINDIN Antibody (aa119-330) - LS-C296492 from LifeSpan Bioscience
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Anti-SPON2 / MINDIN Antibody (aa119-330) - LS-C314984 from LifeSpan Bioscience
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Anti-SPON2 / MINDIN Antibody (aa85-98) - LS-C112986 from LifeSpan Bioscience
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