Gene Symbol | SPON2 |
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Entrez Gene | 10417 |
Alt Symbol | DIL-1, DIL1, M-SPONDIN, MINDIN |
Species | Human |
Gene Type | protein-coding |
Description | spondin 2, extracellular matrix protein |
Other Description | differentially expressed in cancerous and non-cancerous lung cells 1|spondin-2 |
Swissprots | Q9ULW1 Q9BUD6 Q4W5N4 D3DVN9 |
Accessions | AAY40988 CAF85941 EAW82604 EAW82605 EAW82606 Q9BUD6 AA864573 AB027466 BAA85892 AK024499 BAB15789 AK026054 AK074618 BAC11092 AK074770 BAC11196 AK130164 AY358948 AAQ89307 BC002707 AAH02707 BC036341 AAH36341 BC086866 BY797606 CB104725 DA087369 DA092888 DA201089 DA375259 DB249869 DB254983 NM_001128325 NP_001121797 NM_001199021 NP_001185950 NM_012445 NP_036577 |
Function | Cell adhesion protein that promotes adhesion and outgrowth of hippocampal embryonic neurons. Binds directly to bacteria and their components and functions as an opsonin for macrophage phagocytosis of bacteria. Essential in the initiation of the innate immune response and represents a unique pattern- recognition molecule in the ECM for microbial pathogens (By similarity). Binds bacterial lipopolysaccharide (LPS). {ECO:0000250}. |
Subcellular Location | Secreted, extracellular space, extracellular matrix {ECO:0000250}. |
Tissue Specificity | Expressed in normal lung tissue but not in lung carcinoma cell lines. {ECO:0000269|PubMed:10512675}. |
Human SPON2 full length protein - ab160977 from Abcam
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SPON2 / MINDIN Antibody Blocking Peptide - LS-E27818 from LifeSpan Bioscience
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SPON2 / MINDIN Antibody Blocking Peptide - LS-E27339 from LifeSpan Bioscience
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SPON2 / MINDIN Antibody Blocking Peptide - LS-E18821 from LifeSpan Bioscience
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SPON2 / MINDIN Antibody Blocking Peptide - LS-E18820 from LifeSpan Bioscience
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Recombinant Human Mindin/Spondin-2 Protein - H00010417-P01 from Novus Biologicals
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SPON2-Antibody-N-term-Blocking-peptide - BP11576a from Abgent, a WuXi AppTec company
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Spondin 2/Mindin blocking peptide - GTX88064-PEP from GeneTex
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Goat anti SPON2 antibody Immunizing peptide - orb59803 from Biorbyt
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SPON2 Blocking Peptide - 33R-3604 from Fitzgerald
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SPON2 Blocking Peptide - 33R-1803 from Fitzgerald
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Human Spondin 2 Protein - abx069151 from Abbexa
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SPON1 Peptide - AC21-2163-P from Abcore
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SPON2 Peptide - AC21-2629-P from Abcore
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Spondin 2 / SPON2 - H00010417-P01 from Acris Antibodies
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Spondin 2 / SPON2 - H00010417-P01-10 from Acris Antibodies
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Spondin 2 / SPON2 - H00010417-P01-25 from Acris Antibodies
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R-Spondin-2, Human, Recombinant - 28-10281 from ARP American Research Products
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Spondin 2 (SPON2), Human - 20-9064 from ARP American Research Products
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SPON2 Peptide - 42-564P from ProSci
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SPON2 Peptide - 42-958P from ProSci
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SPON2 fusion protein - Ag14337 from Proteintech Group
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Recombinant Human SPON2, His-tagged - SPON2-2928H from Creative Biomart
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Recombinant Spondin 2 (SPON2) - RPF396Hu01 from Uscn Life Science Inc.
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Recombinant Spondin 2 (SPON2) - RPF396Mu01 from Uscn Life Science Inc.
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