Gene Symbol | PBXIP1 |
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Entrez Gene | 57326 |
Alt Symbol | HPIP |
Species | Human |
Gene Type | protein-coding |
Description | pre-B-cell leukemia homeobox interacting protein 1 |
Other Description | hematopoietic PBX-interacting protein|pre-B-cell leukemia transcription factor interacting protein 1|pre-B-cell leukemia transcription factor-interacting protein 1 |
Swissprots | Q9HD85 Q5T176 Q5T174 Q96AQ6 Q9HA02 Q9H8X6 |
Accessions | EAW53174 EAW53175 EAW53176 Q96AQ6 AF221521 AAG02026 AK022497 BAB14059 AK023219 BAB14471 AK300544 BAG62252 AK300987 BAG62606 AK303413 BAG64466 AK303863 BAG64802 AK310388 AK310712 AK315551 BC016852 AAH16852 EU446600 ABZ92129 U00952 NM_020524 NP_065385 |
Function | Regulator of pre-B-cell leukemia transcription factors (BPXs) function. Inhibits the binding of PBX1-HOX complex to DNA and blocks the transcriptional activity of E2A-PBX1. Tethers estrogen receptor-alpha (ESR1) to microtubules and allows them to influence estrogen receptors-alpha signaling. {ECO:0000269|PubMed:10825160, ECO:0000269|PubMed:12360403, ECO:0000269|PubMed:17043237}. |
Subcellular Location | Cytoplasm, cytoskeleton. Nucleus. Note=Shuttles between the nucleus and the cytosol. Mainly localized in the cytoplasm, associated with microtubules. Detected in small amounts in the nucleus. |
Tissue Specificity | Expressed in early hematopoietic precursors. {ECO:0000269|PubMed:10825160}. |
Human PBXIP1 protein fragment - ab163534 from Abcam
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PBXIP1 / HPIP Antibody Blocking Peptide - LS-E4517 from LifeSpan Bioscience
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PBXIP1 / HPIP Antibody Blocking Peptide - LS-E11600 from LifeSpan Bioscience
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Recombinant Human PBXIP1 Protein - H00057326-Q01 from Novus Biologicals
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PBXIP1-Antibody-C-term-Blocking-Peptide - BP16848b from Abgent, a WuXi AppTec company
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PBXIP1 - H00057326-Q01-10 from Acris Antibodies
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PBXIP1 - H00057326-Q01-25 from Acris Antibodies
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PBXIP1 fusion protein - Ag2746 from Proteintech Group
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Recombinant Human PBXIP1, GST-tagged - PBXIP1-1544H from Creative Biomart
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Recombinant Human Pre-B-cell leukemia transcription factor-interacting protein 1(PBXIP1) - CSB-YP856896HU CSB-EP856896HU CSB-BP856896HU CSB-MP856896HU from Cusabio
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Pre-B-cell leukemia transcription factor-interacting protein 1 (PBXIP1), Recombinant Protein - MBS1364158 from MyBioSource
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PBXIP1 Recombinant Protein Antigen - NBP1-83222PEP from Novus Biologicals
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PBXIP1 Peptide, Human - M34GP11358H from Creative Peptides
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