TULP1

Gene Symbol TULP1
Entrez Gene 7287
Alt Symbol LCA15, RP14, TUBL1
Species Human
Gene Type protein-coding
Description tubby like protein 1
Other Description tubby-related protein 1
Swissprots O43536 Q5TGM5 Q8N571 O00294
Accessions AAB97966 EAX03839 EAX03840 O00294 AB593123 BAJ84063 AB593124 BAJ84064 BC032714 AAH32714 BC065261 AAH65261 CN355966 DQ426893 ABD90544 EU446712 ABZ92241 U82468 AAB53700 NM_001289395 NP_001276324 NM_003322 NP_003313
Function Required for normal development of photoreceptor synapses. Required for normal photoreceptor function and for long- term survival of photoreceptor cells. Interacts with cytoskeleton proteins and may play a role in protein transport in photoreceptor cells (By similarity). Binds lipids, especially phosphatidylinositol 3-phosphate, phosphatidylinositol 4- phosphate, phosphatidylinositol 5-phosphate, phosphatidylinositol 3,4-bisphosphate, phosphatidylinositol 4,5-bisphosphate, phosphatidylinositol 3,4,5-bisphosphate, phosphatidylserine and phosphatidic acid (in vitro). Contribute to stimulation of phagocytosis of apoptotic retinal pigment epithelium (RPE) cells and macrophages. {ECO:0000250, ECO:0000269|PubMed:16303976, ECO:0000269|PubMed:19837063}.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:16303976}. Cell membrane {ECO:0000269|PubMed:16303976}; Peripheral membrane protein {ECO:0000269|PubMed:16303976}; Cytoplasmic side {ECO:0000269|PubMed:16303976}. Secreted {ECO:0000250}. Cell junction, synapse {ECO:0000250}. Note=Detected at synapses between photoreceptor cells and second-order neurons. Does not have a cleavable signal peptide and is secreted by an alternative pathway (By similarity). {ECO:0000250}.
Tissue Specificity Retina-specific.

TULP1 CRISPR/Cas9 KO Plasmid (h) - sc-408678 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TULP1 HDR Plasmid (h) - sc-408678-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TULP1 Double Nickase Plasmid (h) - sc-408678-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TULP1 Double Nickase Plasmid (h2) - sc-408678-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TULP1 CRISPR Activation Plasmid (h) - sc-408678-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TULP1 CRISPR Activation Plasmid (h2) - sc-408678-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TULP1 Lentiviral Activation Particles (h) - sc-408678-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TULP1 Lentiviral Activation Particles (h2) - sc-408678-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TULP1 siRNA (h) - sc-106862 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

TULP1 shRNA Plasmid (h) - sc-106862-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

TULP1 shRNA (h) Lentiviral Particles - sc-106862-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CompoZr® Knockout ZFN Kit - CKOZFN22282 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND22282 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

TULP1 siRNA (Human) - CRH4981 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

TULP1 - MBS8228318 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human TULP1 (NM_003322.3) - SHH437928 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human TULP1(NM_003322.3) - SHL106956 from Creative biogene

Category siRNA
Species Reactivities Human

Human TULP1 siRNA - orb265483 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

TULP1 shRNA Plasmid (Human) - CHH4981 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

TULP1 miRNA 3'UTR clone - MiUTR1H-10883 from Creative biogene

Species Reactivities Human
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