LPAR3

Gene Symbol LPAR3
Entrez Gene 23566
Alt Symbol EDG7, Edg-7, GPCR, HOFNH30, LP-A3, LPA3, RP4-678I3
Species Human
Gene Type protein-coding
Description lysophosphatidic acid receptor 3
Other Description LPA receptor 3|LPA receptor EDG7|LPA-3|calcium-mobilizing lysophosphatidic acid receptor LP-A3|endothelial cell differentiation gene 7|endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor, 7|lysophosphatidic acid receptor Edg-7
Swissprots A0AVA3 Q9UBY5
Accessions CCV20023 EAW73222 Q9UBY5 AF127138 AAD56311 AF186380 AAF00530 AF236117 AAF91291 AK091731 AK308283 AY322547 AAP84360 BC126268 AAI26269 BC126270 AAI26271 BC144021 BU633960 XM_011541149 XP_011539451 NM_012152 NP_036284
Function Receptor for lysophosphatidic acid (LPA), a mediator of diverse cellular activities. May play a role in the development of ovarian cancer. Seems to be coupled to the G(i)/G(o) and G(q) families of heteromeric G proteins.
Subcellular Location Cell membrane; Multi-pass membrane protein.
Tissue Specificity Most abundantly expressed in prostate, testes, pancreas, and heart, with moderate levels in lung and ovary. No detectable expression in brain, placenta, liver, skeletal muscle, kidney, spleen, thymus, small intestine, colon, or peripheral blood leukocytes.
Top Pathways PI3K-Akt signaling pathway, Rap1 signaling pathway, Neuroactive ligand-receptor interaction

EDG-7 (K-19) - sc-16090 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
EDG-7 (K-19): sc-16090. Western blot analysis of EDG-7 expression in SK-N-MC whole cell lysate.

EDG-7 (C-7) - sc-390270 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
EDG-7 (C-7): sc-390270. Western blot analysis of EDG-7 expression in SK-N-MC (A), NTERA-2 cl.D1 (B) and LNCaP (C) whole cell lysates.

EDG-7 (H-60) - sc-25492 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

Anti-EDG7 antibody - ab137497 from Abcam

Prices $376.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-EDG7 antibody (ab137497) at 1/1000 dilutionLane 1 : NT2D1 whole cell lysateLane 2 : PC3 whole cell lysateLysates/proteins at 30 µg per lane.

Anti-EDG7 antibody - ab93905 from Abcam

Prices $376.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
ab93905 at 5 µg/ml staining EDG7 in Formalin-Fixed, Paraffin-Embedded Human heart by immunohistochemistry. Proteinase K digestion was used for antigen retrieval.

Anti-EDG7 antibody - ab135977 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-EDG7 antibody (ab135977) at 1/500 dilution + HT29 cell lysates at 30 µg

Anti-EDG7 antibody - ab16456 from Abcam

Prices $370.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-EDG7 antibody - ab23692 from Abcam

Prices $379.00
Sizes 500 µg
Host Rabbit
Clonality Polyclonal
Anti-EDG7 antibody (ab23692) at 2.5 µg/ml + HepG2 cell lysate (30 µg).

Anti-LPAR3 / LPA3 / EDG7 Antibody (aa333-346) - LS-C3040 from LifeSpan Bioscience

Prices $285.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-LPAR3 / LPA3 / EDG7 Antibody (C-Terminus) - LS-C6474 from LifeSpan Bioscience

Prices $560.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-LPAR3 / LPA3 / EDG7 Antibody (aa1-12) - LS-C22996 from LifeSpan Bioscience

Prices $355.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-LPAR3 / LPA3 / EDG7 Antibody (aa99-148) - LS-C291908 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-LPAR3 / LPA3 / EDG7 Antibody (aa275-324) - LS-C291909 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-LPAR3 / LPA3 / EDG7 Antibody - LS-C109277 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Sample (30 ug of whole cell lysate). A: A431. 10% SDS PAGE. LPAR3 antibody diluted at 1:1000.

Anti-LPAR3 / LPA3 / EDG7 Antibody (Pro324) - LS-C177197 from LifeSpan Bioscience

Prices $345.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of EDG-7 (P324)pAb in extracts from Jurkat cells.

Anti-LPAR3 / LPA3 / EDG7 Antibody (Leu148) - LS-C177144 from LifeSpan Bioscience

Prices $345.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of EDG-7 (L148) pAb in extracts from MCF7 cells.

Anti-LPAR3 / LPA3 / EDG7 Antibody - LS-C26661 from LifeSpan Bioscience

Prices $570.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of anti-EDG-7 CT antibody on RH7777 cell lysates transfected with full length human EDG-7 using Pierce Femto Signal substrate.

Anti-LPAR3 / LPA3 / EDG7 Antibody (aa281-330) - LS-C120647 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Immunofluorescence of A549 cells, using EDG7 Antibody. The picture on the right is treated with the synthesized peptide.

Anti-LPAR3 / LPA3 / EDG7 Antibody (aa111-160) - LS-C120579 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Immunofluorescence of LOVO cells, using EDG7 Antibody. The picture on the right is treated with the synthesized peptide.

Anti-LPAR3 / LPA3 / EDG7 Antibody (aa1-12) IHC-plus™ - LS-B1594 from LifeSpan Bioscience

Prices $395.00
Sizes 1 ea
Host Rabbit
Clonality Polyclonal
Anti-EDG7 antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B1594 concentration 5 ug/ml.

Anti-LPAR3 / LPA3 / EDG7 Antibody (Cytoplasmic Domain) IHC-plus™ - LS-A1017 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-LPAR3 / LPA3 / EDG7 antibody IHC of human Prostate, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Anti-LPAR3 / LPA3 / EDG7 Antibody (Internal) IHC-plus™ - LS-A1016 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-EDG7 antibody LS-A1016 IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Anti-LPAR3 / LPA3 / EDG7 Antibody (Cytoplasmic Domain) IHC-plus™ - LS-A1014 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-EDG7 antibody LS-A1014 IHC of human brain, amygdala. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

LPAR3/LPA3/EDG-7 Antibody - NBP1-84903 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry-Paraffin: LPAR3/LPA3/EDG-7 Antibody [NBP1-84903] - Staining of human testis shows moderate cytoplasmic positivity in cells in seminiferous ducts.

LPAR3/LPA3/EDG-7 Antibody - NBP1-00796 from Novus Biologicals

Prices $349.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: EDG7 Antibody [NBP1-00796] Extracts from MCF7 cells.
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