Gene Symbol | LPAR3 |
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Entrez Gene | 23566 |
Alt Symbol | EDG7, Edg-7, GPCR, HOFNH30, LP-A3, LPA3, RP4-678I3 |
Species | Human |
Gene Type | protein-coding |
Description | lysophosphatidic acid receptor 3 |
Other Description | LPA receptor 3|LPA receptor EDG7|LPA-3|calcium-mobilizing lysophosphatidic acid receptor LP-A3|endothelial cell differentiation gene 7|endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor, 7|lysophosphatidic acid receptor Edg-7 |
Swissprots | A0AVA3 Q9UBY5 |
Accessions | CCV20023 EAW73222 Q9UBY5 AF127138 AAD56311 AF186380 AAF00530 AF236117 AAF91291 AK091731 AK308283 AY322547 AAP84360 BC126268 AAI26269 BC126270 AAI26271 BC144021 BU633960 XM_011541149 XP_011539451 NM_012152 NP_036284 |
Function | Receptor for lysophosphatidic acid (LPA), a mediator of diverse cellular activities. May play a role in the development of ovarian cancer. Seems to be coupled to the G(i)/G(o) and G(q) families of heteromeric G proteins. |
Subcellular Location | Cell membrane; Multi-pass membrane protein. |
Tissue Specificity | Most abundantly expressed in prostate, testes, pancreas, and heart, with moderate levels in lung and ovary. No detectable expression in brain, placenta, liver, skeletal muscle, kidney, spleen, thymus, small intestine, colon, or peripheral blood leukocytes. |
Top Pathways | PI3K-Akt signaling pathway, Rap1 signaling pathway, Neuroactive ligand-receptor interaction |
Human EDG7 full length protein - ab161692 from Abcam
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LPAR3 / LPA3 / EDG7 Antibody Blocking Peptide - LS-E28095 from LifeSpan Bioscience
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LPAR3 / LPA3 / EDG7 Antibody Blocking Peptide - LS-E28096 from LifeSpan Bioscience
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LPAR3 / LPA3 / EDG7 Antibody Blocking Peptide - LS-E28097 from LifeSpan Bioscience
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Recombinant Human LPAR3/LPA3/EDG-7 Protein - H00023566-P01 from Novus Biologicals
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EDG7 Blocking Peptide - abx063777 from Abbexa
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EDG7 / LPAR3 - H00023566-G01 from Acris Antibodies
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EDG7 / LPAR3 - H00023566-P01 from Acris Antibodies
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LPAR3 fusion protein - Ag17925 from Proteintech Group
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Recombinant Human LPAR3, GST-tagged - LPAR3-618H from Creative Biomart
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Recombinant Lysophosphatidic Acid Receptor 3 (LPAR3) - RPF543Hu01 from Uscn Life Science Inc.
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Recombinant Lysophosphatidic Acid Receptor 3 (LPAR3) - RPF543Mu01 from Uscn Life Science Inc.
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Recombinant Lysophosphatidic Acid Receptor 3 (LPAR3) - RPF543Mu02 from Uscn Life Science Inc.
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EDG7 Blocking Peptide - CBP2583 from Cohesion Biosciences
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EDG7 Blocking Peptide - CBP3399 from Cohesion Biosciences
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EDG-7 (L148) Peptide - BS2698P from Bioworld Technology
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EDG-7 (P324) Peptide - BS2791P from Bioworld Technology
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LPAR3 Peptide (OEEG01117) - OEEG01117 from Aviva Systems Biology
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Recombinant Human LPAR3/LPA3/EDG-7 Protein - H00023566-G01 from Novus Biologicals
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LPAR3/LPA3/EDG-7 Recombinant Protein Antigen - NBP1-84903PEP from Novus Biologicals
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EDG7 Blocking Peptide - abx162261 from Abbexa
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EDG7-Antibody-C-term-Blocking-Peptide - BP6143a from Abgent, a WuXi AppTec company
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LPAR3 Peptide, Human - M34GP08808H from Creative Peptides
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LPAR3 peptide - orb218446 from Biorbyt
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