Gene Symbol | SNRPB |
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Entrez Gene | 6628 |
Alt Symbol | CCMS, COD, SNRPB1, Sm-B/B', SmB/B', SmB/SmB', snRNP-B |
Species | Human |
Gene Type | protein-coding |
Description | small nuclear ribonucleoprotein polypeptides B and B1 |
Other Description | B polypeptide of Sm protein|Sm protein B/B'|sm-B/Sm-B'|small nuclear ribonucleoprotein polypeptide B|small nuclear ribonucleoprotein polypeptides B and B'|small nuclear ribonucleoprotein-associated proteins B and B' |
Swissprots | Q9UIS5 Q15490 P14678 Q6IB35 |
Accessions | AAD54488 AAD54489 CAA37170 CAA37171 CAH05601 EAX10596 EAX10597 EAX10598 EAX10599 P14678 AK301034 BAG62648 AK301206 BAG62782 AK307093 AK307266 AK312620 BAG35506 AY742712 AAU89981 BC003530 BC080516 AAH80516 BM559678 CR456969 CAG33250 HQ447543 ADQ32029 J04564 AAA60151 M34081 AAA36578 M34082 AAA36579 X15893 CAA33902 X17567 CAB57867 X17568 CAB57868 NM_003091 NP_003082 NM_198216 NP_937859 |
Function | Core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in an heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP. As part of the U7 snRNP it is involved in histone 3'-end processing. {ECO:0000269|PubMed:18984161}. |
Subcellular Location | Cytoplasm, cytosol {ECO:0000269|PubMed:18984161}. Nucleus {ECO:0000269|PubMed:18984161}. Note=SMN-mediated assembly into core snRNPs occurs in the cytosol before SMN-mediated transport to the nucleus to be included in spliceosomes. |
Top Pathways | Systemic lupus erythematosus, Spliceosome |
Cholesterol Oxidase full length protein - ab59077 from Abcam
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Human SNRPB protein fragment - ab117001 from Abcam
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SNRPB / COD Antibody Blocking Peptide - LS-E14753 from LifeSpan Bioscience
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SNRPB / COD Antibody Blocking Peptide - LS-E14752 from LifeSpan Bioscience
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SNRPB / COD Antibody Blocking Peptide - LS-E7231 from LifeSpan Bioscience
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Recombinant Human SNRPB Protein - H00006628-Q01 from Novus Biologicals
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SNRPB-Antibody-N-term-R49-Blocking-Peptide - BP2959a from Abgent, a WuXi AppTec company
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Human SNRPB protein - orb169320 from Biorbyt
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snRNP B protein - 30R-2125 from Fitzgerald
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SNRPB Blocking Peptide - 33R-5358 from Fitzgerald
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SNRPB Blocking Peptide - 33R-2018 from Fitzgerald
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SNRPB - H00006628-Q01-10 from Acris Antibodies
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SNRPB - H00006628-Q01-25 from Acris Antibodies
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Small Nuclear Ribonucleoprotein Polypeptide B, Human Recombinant - 228-12971-1 from RayBiotech
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Recombinant Human Small Nuclear Ribonucleoprotein Polypeptide B - 228-12971-2 from RayBiotech
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Recombinant Human Small Nuclear Ribonucleoprotein Polypeptide B - 228-12971-3 from RayBiotech
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SNRPB fusion protein - ag10298 from Proteintech Group
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Recombinant Human SNRPB2 protein - BP002062-PRO-217 from Syd Labs
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Small Nuclear Ribonucleoprotein Polypeptide B Protein (Recombinant) - abx262815 from Abbexa
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SNRPB (transcript variant 1) - TP320701 from Acris Antibodies
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Small Nuclear Ribonucleoprotein Polypeptide B Human Recombinant ( SNRPB2 Human ) - PT_72254 from Novatein Biosciences
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SNRPB Peptide, Human - M34GP14823H from Creative Peptides
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SNRPB Recombinant Protein Antigen - NBP2-56420PEP from Novus Biologicals
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Small Nuclear Ribonucleoprotein, Recombinant Protein - MBS145492 from MyBioSource
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