SNRPB

Gene Symbol SNRPB
Entrez Gene 6628
Alt Symbol CCMS, COD, SNRPB1, Sm-B/B', SmB/B', SmB/SmB', snRNP-B
Species Human
Gene Type protein-coding
Description small nuclear ribonucleoprotein polypeptides B and B1
Other Description B polypeptide of Sm protein|Sm protein B/B'|sm-B/Sm-B'|small nuclear ribonucleoprotein polypeptide B|small nuclear ribonucleoprotein polypeptides B and B'|small nuclear ribonucleoprotein-associated proteins B and B'
Swissprots Q9UIS5 Q15490 P14678 Q6IB35
Accessions AAD54488 AAD54489 CAA37170 CAA37171 CAH05601 EAX10596 EAX10597 EAX10598 EAX10599 P14678 AK301034 BAG62648 AK301206 BAG62782 AK307093 AK307266 AK312620 BAG35506 AY742712 AAU89981 BC003530 BC080516 AAH80516 BM559678 CR456969 CAG33250 HQ447543 ADQ32029 J04564 AAA60151 M34081 AAA36578 M34082 AAA36579 X15893 CAA33902 X17567 CAB57867 X17568 CAB57868 NM_003091 NP_003082 NM_198216 NP_937859
Function Core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in an heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP. As part of the U7 snRNP it is involved in histone 3'-end processing. {ECO:0000269|PubMed:18984161}.
Subcellular Location Cytoplasm, cytosol {ECO:0000269|PubMed:18984161}. Nucleus {ECO:0000269|PubMed:18984161}. Note=SMN-mediated assembly into core snRNPs occurs in the cytosol before SMN-mediated transport to the nucleus to be included in spliceosomes.
Top Pathways Systemic lupus erythematosus, Spliceosome

Sm B/B'/N (A-10) - sc-271094 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Sm B/B'/N (A-10): sc-271094. Western blot analysis of Sm B/B'/N expression in HeLa (A) and K-562 (B) nuclear extracts.

Sm B/B'/N (FL-240) - sc-25372 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Sm B/B'/N (FL-240): sc-25372. Immunoperoxidase staining of formalin fixed, paraffin-embedded human duodenum tissue showing nuclear staining of glandular cells at low (A) and high (B) magnification. Kindly provided by The Swedish Human Protein Atlas (HPA) program.

Sm B/B'/N (H-9) - sc-374078 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Sm B/B'/N (H-9): sc-374078. Western blot analysis of Sm B/B'/N expression in K-562 (A), HeLa (B) and KNRK (C) nuclear extracts.

Sm B/B'/N (12F5) - sc-130670 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Sm B/B'/N (12F5): sc-130670. Western blot analysis of Sm B/B'/N expression in HeLa whole cell lysate.

Sm B/B'/N (N-18) - sc-5485 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Sm B/B/N (N-18): sc-5485. Western blot analysis of Sm B expression in K-562 nuclear extract.

Anti-SNRPB antibody - ab155026 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-SNRPB antibody (ab155026) at 1/1000 dilution + Hela nuclear lysate at 30 µg

Anti-SNRPB antibody - ab85534 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-SNRPB antibody (ab85534) at 1 µg/ml + 293T cell lysate at 10 µgSecondaryHRP conjugated anti-Rabbit IgG at 1/50000 dilution

Anti-SNRPB / COD Antibody (Internal) - LS-C345730 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot of RSMB Antibody with human Fetal Lung lysate.

Anti-SNRPB / COD Antibody (aa72-121) - LS-C101844 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
SNRPB antibody LS-C101844 Western blot of 293T cell lysate.

Anti-SNRPB / COD Antibody (clone 1B4) - LS-C198235 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 1B4
Detection limit for recombinant GST tagged SNRPB is 3 ng/ml as a capture antibody.

Anti-SNRPB / COD Antibody (aa35-84) - LS-C110521 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
SNRPB antibody LS-C110521 Western blot of HT1080 cell lysate.

Anti-SNRPB / COD Antibody (aa34-65) - LS-C161352 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Western blot of SNRPB Antibody (N-term R49) in T47D cell line lysates (35 ug/lane). SNRPB (arrow) was detected using the purified antibody.

SNRPB Antibody - NBP1-32174 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: SNRPB Antibody [NBP1-32174] - Sample (30 ug of whole cell lysate) A: HeLa nucleus 12% SDS PAGE; antibody diluted at 1:1000.

SNRPB Antibody - NBP1-57215 from Novus Biologicals

Prices $139.00, $329.00
Sizes 20 µl, 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: SNRPB Antibody [NBP1-57215] - HT1080 cell lysate, concentration 0.2-1 ug/ml.

SNRPB Antibody - NBP1-57237 from Novus Biologicals

Prices $139.00, $329.00
Sizes 20 µl, 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: SNRPB Antibody [NBP1-57237] - 293T cells lysate, concentration 0.2-1 ug/ml.

SNRPB Antibody - H00006628-D01P from Novus Biologicals

Prices $399.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: SNRPB Antibody [H00006628-D01P] - Analysis of SNRPB expression in transfected 293T cell line by SNRPB polyclonal antibody.Lane 1: SNRPB transfected lysate(24.60 KDa).Lane 2: Non-transfected lysate.

SNRPB Antibody - H00006628-A01 from Novus Biologicals

Host Mouse
Clonality Polyclonal

SNRPB Antibody (1B4) - H00006628-M01A from Novus Biologicals

Prices $349.00
Sizes 200 µl
Host Mouse
Clonality Monoclonal
Clone 1B4

SNRPB Antibody (1B4) - H00006628-M01 from Novus Biologicals

Prices $349.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 1B4

Anti-SNRPB antibody produced in rabbit - SAB2102256 from Sigma-Aldrich

Prices $347.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-SNRPB: <B>Cat. No.SAB2102256</B>: SNRPB in 293T cell lysate with SNRPB antibody at 1.0 μg/mL.

Monoclonal Anti-SmB antibody produced in mouse - S0698 from Sigma-Aldrich

Prices $59.70, $355.00, $461.00
Sizes 25 µl, 100 µl, 200 µl
Host Mouse
Clonality Monoclonal
Clone 12F5

Anti-SNRPB, (N-terminal) antibody produced in rabbit - SAB2104542 from Sigma-Aldrich

Prices $347.50, $347.50
Sizes 50 µg, 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-SNRPB, antibody produced in rabbit: <B>Cat. No. SAB2104542</B>: Immunoblotting analysis of SNRPB in HT1080 cell lysate with SNRPB anitbody at 1 μg/mL.

Anti-SNRPB antibody produced in rabbit - SAB1411303 from Sigma-Aldrich

Prices $347.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-SNRPB: <B>Cat. No. SAB1411303</B>: Antibody concentration: 0.1-5 μg/mL. Specific band of ~24.6 kDa using SNRPB transfected 293T lysate.<BR/><B>Lanes</B><BR/>1. Transfected 293T lysate.<BR/>2. Non-transfected 293T lysate.

Monoclonal Anti-SNRPB, (N-terminal) antibody produced in mouse - SAB1402925 from Sigma-Aldrich

Prices $347.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone 1B4

SNRPB antibody - middle region (ARP40443_P050) - ARP40443_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
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