NHEJ1

Gene Symbol	NHEJ1
Entrez Gene	79840
Alt Symbol	XLF
Species	Human
Gene Type	protein-coding
Description	nonhomologous end-joining factor 1
Other Description	XRCC4-like factor|non-homologous end-joining factor 1|protein cernunnos
Swissprots	Q6IA64 Q96JS9 Q4ZFW7 B8ZZA4 Q9H9Q4
Accessions	AAX88921 EAW70678 Q9H9Q4 AJ972687 CAI99410 AK022672 BAB14168 BC008210 AAH08210 BC012732 AAH12732 BC030986 AAH30986 CR457291 CAG33572 DB124934 NM_024782 NP_079058
Function	DNA repair protein involved in DNA nonhomologous end joining (NHEJ) required for double-strand break (DSB) repair and V(D)J recombination. May serve as a bridge between XRCC4 and the other NHEJ factors located at DNA ends, or may participate in reconfiguration of the end bound NHEJ factors to allow XRCC4 access to the DNA termini. It may act in concert with XRCC6/XRCC5 (Ku) to stimulate XRCC4-mediated joining of blunt ends and several types of mismatched ends that are noncomplementary or partially complementary. {ECO:0000269|PubMed:16439204, ECO:0000269|PubMed:16439205, ECO:0000269|PubMed:17470781}.
Subcellular Location	Nucleus {ECO:0000269|PubMed:16439204, ECO:0000269|PubMed:16439205}.
Tissue Specificity	Ubiquitously expressed. {ECO:0000269|PubMed:16439204}.
Top Pathways	Non-homologous end-joining

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human XLF full length protein - ab132333 from Abcam Category Protein Source Wheat germ Species Human

Human XLF peptide - ab27783 from Abcam Category Peptide

Human XLF protein fragment - ab131670 from Abcam Category Protein Source E. coli Species Human

NHEJ1 / XLF Antibody Blocking Peptide - LS-E3333 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

NHEJ1 / XLF Antibody Blocking Peptide - LS-E22510 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

NHEJ1 / XLF Antibody Blocking Peptide - LS-E26177 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

XLF Recombinant Protein - H00079840-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human XLF Protein - NBP2-23291 from Novus Biologicals Category Protein Prices $269.00 Sizes 20 µg Source E.coli Species Human

NHEJ1-Antibody-C-term-Blocking-Peptide - BP14503b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

XLF blocking peptide - GTX89244-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human, Dog

Human NHEJ1 protein - orb168924 from Biorbyt Category Protein Prices $170.00, $289.00, $1,139.00 Sizes 2 μg, 10 μg, 100 μg Source E.coli

NHEJ1 protein (His tag) - 80R-2428 from Fitzgerald Category Protein Prices $270.00 Sizes 20 µg Source E.coli

XLF Peptide - AC21-1008-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

NHEJ1 / Protein cernunnos (1-224, His-tag) - AR50508PU-N from Acris Antibodies Category Protein Prices $790.00 Sizes 100 µg Source E. coli Species Human

NHEJ1 / Protein cernunnos (1-224, His-tag) - AR50508PU-S from Acris Antibodies Category Protein Prices $340.00 Sizes 20 µg Source E. coli Species Human

NHEJ1 / Protein cernunnos - H00079840-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

NHEJ1 / Protein cernunnos - H00079840-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

NHEJ1, 1-224aa, Human, His tag, E.coli - 01-P1684 from ARP American Research Products Category Protein Prices $139.00, $369.00, $849.00 Sizes 5 µg, 20 µg, 100 µg Species Human

NHEJ1 Peptide - 45-966P from ProSci Category Peptide Species Human

NHEJ1 fusion protein - Ag2496 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

NHEJ1 Human - PRPS-1200 from NeoScientific Category Protein Prices $65.00, $169.00, $1,560.00 Sizes 2 µg, 10 µg, 100 µg Source E.coli. Species Human

Recombinant Human NHEJ1 Protein - BP002934-PRO-1193 from Syd Labs Category Protein Prices $160.00, $1,200.00 Sizes 10 µg, 100 µg Source E. coli-derived. Species Human

NHEJ1, 1-224aa, Recombinant Protein - GWB-P0354C from Genway Biotech Category Protein Prices $300.00, $900.00 Sizes 20 μg, 100 μg Source E.coli Species Human

Recombinant Human NHEJ1, GST-tagged - NHEJ1-1290H from Creative Biomart Category Protein Source E.coli Species Human

NHEJ1 - PAT-80574-1 from Nordic BioSite Category Protein Species Human

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