NHEJ1

Gene Symbol NHEJ1
Entrez Gene 79840
Alt Symbol XLF
Species Human
Gene Type protein-coding
Description nonhomologous end-joining factor 1
Other Description XRCC4-like factor|non-homologous end-joining factor 1|protein cernunnos
Swissprots Q6IA64 Q96JS9 Q4ZFW7 B8ZZA4 Q9H9Q4
Accessions AAX88921 EAW70678 Q9H9Q4 AJ972687 CAI99410 AK022672 BAB14168 BC008210 AAH08210 BC012732 AAH12732 BC030986 AAH30986 CR457291 CAG33572 DB124934 NM_024782 NP_079058
Function DNA repair protein involved in DNA nonhomologous end joining (NHEJ) required for double-strand break (DSB) repair and V(D)J recombination. May serve as a bridge between XRCC4 and the other NHEJ factors located at DNA ends, or may participate in reconfiguration of the end bound NHEJ factors to allow XRCC4 access to the DNA termini. It may act in concert with XRCC6/XRCC5 (Ku) to stimulate XRCC4-mediated joining of blunt ends and several types of mismatched ends that are noncomplementary or partially complementary. {ECO:0000269|PubMed:16439204, ECO:0000269|PubMed:16439205, ECO:0000269|PubMed:17470781}.
Subcellular Location Nucleus {ECO:0000269|PubMed:16439204, ECO:0000269|PubMed:16439205}.
Tissue Specificity Ubiquitously expressed. {ECO:0000269|PubMed:16439204}.
Top Pathways Non-homologous end-joining

XLF CRISPR/Cas9 KO Plasmid (h) - sc-405474 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

XLF HDR Plasmid (h) - sc-405474-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

XLF Double Nickase Plasmid (h) - sc-405474-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

XLF Double Nickase Plasmid (h2) - sc-405474-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

XLF CRISPR Activation Plasmid (h) - sc-405474-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

XLF CRISPR Activation Plasmid (h2) - sc-405474-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

XLF Lentiviral Activation Particles (h) - sc-405474-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

XLF Lentiviral Activation Particles (h2) - sc-405474-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

XLF siRNA (h) - sc-76936 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

XLF shRNA Plasmid (h) - sc-76936-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

XLF shRNA (h) Lentiviral Particles - sc-76936-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU095931 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN1500 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND1500 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

NHEJ1 siRNA (Human) - CRJ2604 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human NHEJ1 (NM_024782.2) - SHH352204 from Creative biogene

Category siRNA
Species Reactivities Human

Human NHEJ1 siRNA - orb273105 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

NHEJ1 shRNA Plasmid (Human) - CHJ2604 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

NHEJ1 miRNA 3'UTR clone - MiUTR3H-11778 from Creative biogene

Species Reactivities Human
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