Gene Symbol | SORBS3 |
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Entrez Gene | 10174 |
Alt Symbol | SCAM-1, SCAM1, SH3D4 |
Species | Human |
Gene Type | protein-coding |
Description | sorbin and SH3 domain containing 3 |
Other Description | sorbin and SH3 domain-containing protein 3|vinexin|vinexin beta (SH3-containing adaptor molecule-1) |
Swissprots | Q6NX54 Q5BJE4 Q96FY4 Q9UQE4 O60504 |
Accessions | EAW63673 EAW63674 EAW63675 EAW63676 O60504 AF037261 AAC09244 AF064807 AAD32304 AK301196 BAG62776 AK303950 BAG64877 BC004314 AAH04314 BC010146 AAH10146 BC067260 AAH67260 BC091514 AAH91514 BM999851 CF456833 CX783871 XM_005273371 XP_005273428 XM_006716266 XP_006716329 XM_006716268 XP_006716331 NM_001018003 NP_001018003 NM_005775 NP_005766 |
Function | Vinexin alpha isoform promotes up-regulation of actin stress fiber formation. Vinexin beta isoform plays a role in cell spreading and enhances the activation of JNK/SAPK in response to EGF stimulation by using its third SH3 domain. |
Subcellular Location | Isoform Alpha: Cell junction {ECO:0000250}. Cytoplasm, cytoskeleton {ECO:0000250}. Note=Localized at cell- extracellular matrix junctions (By similarity). Both isoforms were localized at focal adhesion and cell-cell adhesion sites. {ECO:0000250}. |
Tissue Specificity | Both isoforms are expressed in different tissues like heart, placenta, brain, skeletal muscle and pancreas. Isoform beta is especially found in liver. |
Vinexin (D-4) - sc-398275 from Santa Cruz Biotechnology
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Vinexin (D-18) - sc-14145 from Santa Cruz Biotechnology
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Vinexin (G-20) - sc-14146 from Santa Cruz Biotechnology
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Vinexin (N-19) - sc-14144 from Santa Cruz Biotechnology
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Anti-Vinexin antibody - ab126971 from Abcam
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Anti-Vinexin antibody - ab126986 from Abcam
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Anti-Vinexin antibody - ab68222 from Abcam
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Anti-SORBS3 / Vinexin Antibody (Internal) - LS-C145068 from LifeSpan Bioscience
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Anti-SORBS3 / Vinexin Antibody - LS-C155413 from LifeSpan Bioscience
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Vinexin Antibody - NBP2-20861 from Novus Biologicals
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Vinexin Antibody - NBP2-20860 from Novus Biologicals
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Vinexin Antibody - H00010174-B01P from Novus Biologicals
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Vinexin Antibody - H00010174-B01 from Novus Biologicals
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Vinexin Polyclonal Antibody - bs-13741R from Bioss
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Vinexin Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-13741R-A350 from Bioss
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Vinexin Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated - bs-13741R-A488 from Bioss
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Vinexin Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated - bs-13741R-A555 from Bioss
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Vinexin Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated - bs-13741R-A647 from Bioss
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Vinexin Polyclonal Antibody, Cy3 Conjugated - bs-13741R-Cy3 from Bioss
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Vinexin Polyclonal Antibody, Cy5 Conjugated - bs-13741R-Cy5 from Bioss
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Vinexin Polyclonal Antibody, Cy5.5 Conjugated - bs-13741R-Cy5.5 from Bioss
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Vinexin Polyclonal Antibody, Cy7 Conjugated - bs-13741R-Cy7 from Bioss
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Vinexin Polyclonal Antibody, FITC Conjugated - bs-13741R-FITC from Bioss
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Vinexin Polyclonal Antibody, Biotin Conjugated - bs-13741R-Biotin from Bioss
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Vinexin Polyclonal Antibody, HRP Conjugated - bs-13741R-HRP from Bioss
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