Gene Symbol | SORBS3 |
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Entrez Gene | 10174 |
Alt Symbol | SCAM-1, SCAM1, SH3D4 |
Species | Human |
Gene Type | protein-coding |
Description | sorbin and SH3 domain containing 3 |
Other Description | sorbin and SH3 domain-containing protein 3|vinexin|vinexin beta (SH3-containing adaptor molecule-1) |
Swissprots | Q6NX54 Q5BJE4 Q96FY4 Q9UQE4 O60504 |
Accessions | EAW63673 EAW63674 EAW63675 EAW63676 O60504 AF037261 AAC09244 AF064807 AAD32304 AK301196 BAG62776 AK303950 BAG64877 BC004314 AAH04314 BC010146 AAH10146 BC067260 AAH67260 BC091514 AAH91514 BM999851 CF456833 CX783871 XM_005273371 XP_005273428 XM_006716266 XP_006716329 XM_006716268 XP_006716331 NM_001018003 NP_001018003 NM_005775 NP_005766 |
Function | Vinexin alpha isoform promotes up-regulation of actin stress fiber formation. Vinexin beta isoform plays a role in cell spreading and enhances the activation of JNK/SAPK in response to EGF stimulation by using its third SH3 domain. |
Subcellular Location | Isoform Alpha: Cell junction {ECO:0000250}. Cytoplasm, cytoskeleton {ECO:0000250}. Note=Localized at cell- extracellular matrix junctions (By similarity). Both isoforms were localized at focal adhesion and cell-cell adhesion sites. {ECO:0000250}. |
Tissue Specificity | Both isoforms are expressed in different tissues like heart, placenta, brain, skeletal muscle and pancreas. Isoform beta is especially found in liver. |
Human Vinexin full length protein - ab160858 from Abcam
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Human Vinexin full length protein - ab177680 from Abcam
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Vinexin Recombinant Protein - H00010174-P01 from Novus Biologicals
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SORBS3 protein (His tag) - 80R-3637 from Fitzgerald
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SORBS3 / SCAM1 (1-329, His-tag) - AR51324PU-N from Acris Antibodies
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SORBS3 / SCAM1 (1-329, His-tag) - AR51324PU-S from Acris Antibodies
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SORBS3 / SCAM1 - H00010174-P01-10 from Acris Antibodies
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SORBS3 / SCAM1 - H00010174-P01-25 from Acris Antibodies
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SORBS3, 1-329aa, Human, His tag, E.coli - 01-P2504 from ARP American Research Products
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Recombinant Human SORBS3, His-tagged - SORBS3-5008H from Creative Biomart
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Recombinant Human sorbin and SH3 domain containing 3, His-tagged - SORBS3-407H from Creative Biomart
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Vinexin (Sorbs3/SH3-P3) peptide - pep0608 from Covalab
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Recombinant Human Vinexin(SORBS3) - CSB-YP022406HU CSB-EP022406HU CSB-BP022406HU CSB-MP022406HU from Cusabio
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SORBS3, 1-329aa, Human, His tag, E.coli - ATGP2504 from ATGen
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Sorbin And SH3 Domain Containing 3 Protein (Recombinant) - abx263403 from Abbexa
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Vinexin (SORBS3) , Recombinant Protein - MBS1226674 from MyBioSource
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Human SORBS3 protein - orb260102 from Biorbyt
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Vinexin Recombinant Protein Antigen - NBP1-87084PEP from Novus Biologicals
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SORBS3 Peptide, Human - M34GP14893H from Creative Peptides
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Recombinant Human Vinexin Protein - NBP2-51520 from Novus Biologicals
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SORBS3 - PAT-82503-1 from Nordic BioSite
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SORBS3 - PAT-82503-2 from Nordic BioSite
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Sorbin And SH3 Domain Containing 3, Human Recombinant - 228-21937-1 from RayBiotech
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Vinexin Recombinant Protein Antigen - NBP2-56623PEP from Novus Biologicals
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Sorbin And SH3 Domain Containing 3, Recombinant Protein - MBS146455 from MyBioSource
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