PRDM16

Gene Symbol PRDM16
Entrez Gene 63976
Alt Symbol CMD1LL, LVNC8, MEL1, PFM13
Species Human
Gene Type protein-coding
Description PR domain containing 16
Other Description MDS1/EVI1-like gene 1|PR domain zinc finger protein 16|transcription factor MEL1
Swissprots Q9HAZ2 Q8WYJ9 B1AJP9 B1AJP8 B1AJP7 A6NHQ8 B1WB48 Q9C0I8
Accessions CCQ43680 EAW71449 EAW71450 EAW71451 Q9HAZ2 AB051462 BAB21766 AB078876 BAB84297 AF294278 AAG33382 AI623202 AK093853 AK094178 AK309078 BC110593 BC161614 AAI61614 BC168363 AAI68363 BQ897896 BX092842 XM_005244772 XP_005244829 XM_005244773 XP_005244830 XM_005244774 XP_005244831 XM_006710814 XP_006710877 XM_011541944 XP_011540246 XM_011541945 XP_011540247 NM_022114 NP_071397 NM_199454 NP_955533
Function Binds DNA and functions as a transcriptional regulator. Functions in the differentiation of brown adipose tissue (BAT) which is specialized in dissipating chemical energy in the form of heat in response to cold or excess feeding while white adipose tissue (WAT) is specialized in the storage of excess energy and the control of systemic metabolism. Together with CEBPB, regulates the differentiation of myoblastic precursors into brown adipose cells. Functions also as a repressor of TGF-beta signaling. Isoform 4 may regulate granulocytes differentiation. {ECO:0000269|PubMed:12816872, ECO:0000269|PubMed:14656887, ECO:0000269|PubMed:19049980}.
Subcellular Location Nucleus {ECO:0000269|PubMed:19049980}.
Tissue Specificity Expressed in uterus and kidney. Expressed in both cardiomyocytes and interstitial cells. {ECO:0000269|PubMed:11050005, ECO:0000269|PubMed:12816872, ECO:0000269|PubMed:23768516}.

PRDM16 (E-20) - sc-55695 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

PRDM16 (P-20) - sc-55699 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

PRDM16 (K-18) - sc-55697 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
PRDM16 (K-18): sc-55697. Western blot analysis of PRDM16 expression in Jurkat whole cell lysate.

PRDM16 (N-15) - sc-55698 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

PRDM16 (N-16) - sc-130243 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal
PRDM16 (N-16): sc-130243. Immunoperoxidase staining of formalin fixed, paraffin-embedded human cancer tissue showing cytoplasmic staining.

Anti-PRDM16 antibody - ab202344 from Abcam

Prices $359.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-PRDM16 antibody (ab202344) at 1/1000 dilutionLane 1 : LNCaP cell line lysateLane 2 : Mouse lung tissue lysateLysates/proteins at 35 µg per lane.SecondaryGoat anti-rabbit IgG H&L(HRP) at 1/10000 dilution

Anti-PRDM16 antibody - ab106410 from Abcam

Prices $394.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Lane 1 : Anti-PRDM16 antibody (ab106410) at 1 µg/mlLane 2 : Anti-PRDM16 antibody (ab106410) at 2 µg/mlLane 1 : Rat brain tissue lysate Lane 2 : Rat brain tissue lysate Lysates/proteins at 15 µg per lane.

Anti-PRDM16 antibody - ab118573 from Abcam

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
ab118573, at 5 µg/ml, staining PRDM16 in formalin-fixed, paraffin-embedded Human Skin tissue by Immunohistochemistry.

Anti-PRDM16 antibody - ab85874 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-PRDM16 antibody (ab85874) at 1 µg/mlLane 1 : HeLa (Human epithelial carcinoma cell line) Whole Cell LysateLane 2 : Jurkat (Human T cell lymphoblast-like cell line) Whole Cell LysateLane 3 : HEK293 (Human embryonic kidney cell line) Whole Cell LysateLysates/proteins at 10 µg/ml per lane.SecondaryGoat polyclonal to Rabbit IgG - H&L - Pre-Adsorbed (HRP) at 1/3000 dilutiondeveloped using the ECL techniquePerformed under reducing conditions.

Anti-PRDM16 Antibody - LS-C98756 from LifeSpan Bioscience

Prices $530.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-PRDM16 Antibody (aa1264-1276) - LS-C55309 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Anti-PRDM16 Antibody (aa13-316, AP) - LS-C245429 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PRDM16 Antibody (aa13-316, Biotin) - LS-C245431 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PRDM16 Antibody (aa13-316, APC) - LS-C245430 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PRDM16 Antibody (aa13-316, FITC) - LS-C245432 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PRDM16 Antibody (aa13-316, PE) - LS-C245433 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PRDM16 Antibody (aa13-316, Azide-free, HRP) - LS-C247781 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PRDM16 Antibody (aa1213-1276) - LS-C311630 from LifeSpan Bioscience

Prices $250.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-PRDM16 Antibody (aa13-316) - LS-C328297 from LifeSpan Bioscience

Prices $425.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PRDM16 Antibody (aa539-588) - LS-C115968 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
PRDM16 antibody LS-C115968 Western blot of HepG2 cell lysate.

Anti-PRDM16 Antibody (aa771-804) - LS-C344432 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Western blot of lysates from LNCaP cell line, mouse lung tissue lysate (from left to right) with PRDM16 Antibody. Antibody was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L (HRP) at 1:10000 dilution was used as the secondary antibody. Lysates at 35 ug per lane.

Anti-PRDM16 Antibody (C-Terminus) IHC-plus™ - LS-B4625 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-PRDM16 antibody IHC of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4625 concentration 5 ug/ml.

PRDM16/MEL1 Antibody [Unconjugated] - AF6295 from Novus Biologicals

Prices $99.00, $359.00
Sizes 25 µg, 100 µg
Host Sheep
Clonality Polyclonal
Western blot shows lysates of K562 human chronic myelogenous leukemia cell line. PVDF Membrane was probed with 1 µg/mL of Sheep Anti-Human/Mouse PRDM16 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF6295) followed by HRP-conjugated Anti-Sheep IgG Secondary Antibody (Catalog # HAF016). A specific band was detected for PRDM16 at approximately 170 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 8.

PRDM16/MEL1 Antibody - NBP1-77096 from Novus Biologicals

Prices $329.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: PRDM16/MEL1 Antibody [NBP1-77096] - Analysis of PRDM16 in K562 cell lysate with PRDM16 antibody at 1 ug/mL.

PRDM16/MEL1 Antibody - NBP1-71992 from Novus Biologicals

Prices $369.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western Blot: PRDM16/MEL1 Antibody [NBP1-71992] - Analysis of anti-PRDM16 antibody with rat brain tissue lysate.
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