PRDM16

Gene Symbol PRDM16
Entrez Gene 63976
Alt Symbol CMD1LL, LVNC8, MEL1, PFM13
Species Human
Gene Type protein-coding
Description PR domain containing 16
Other Description MDS1/EVI1-like gene 1|PR domain zinc finger protein 16|transcription factor MEL1
Swissprots Q9HAZ2 Q8WYJ9 B1AJP9 B1AJP8 B1AJP7 A6NHQ8 B1WB48 Q9C0I8
Accessions CCQ43680 EAW71449 EAW71450 EAW71451 Q9HAZ2 AB051462 BAB21766 AB078876 BAB84297 AF294278 AAG33382 AI623202 AK093853 AK094178 AK309078 BC110593 BC161614 AAI61614 BC168363 AAI68363 BQ897896 BX092842 XM_005244772 XP_005244829 XM_005244773 XP_005244830 XM_005244774 XP_005244831 XM_006710814 XP_006710877 XM_011541944 XP_011540246 XM_011541945 XP_011540247 NM_022114 NP_071397 NM_199454 NP_955533
Function Binds DNA and functions as a transcriptional regulator. Functions in the differentiation of brown adipose tissue (BAT) which is specialized in dissipating chemical energy in the form of heat in response to cold or excess feeding while white adipose tissue (WAT) is specialized in the storage of excess energy and the control of systemic metabolism. Together with CEBPB, regulates the differentiation of myoblastic precursors into brown adipose cells. Functions also as a repressor of TGF-beta signaling. Isoform 4 may regulate granulocytes differentiation. {ECO:0000269|PubMed:12816872, ECO:0000269|PubMed:14656887, ECO:0000269|PubMed:19049980}.
Subcellular Location Nucleus {ECO:0000269|PubMed:19049980}.
Tissue Specificity Expressed in uterus and kidney. Expressed in both cardiomyocytes and interstitial cells. {ECO:0000269|PubMed:11050005, ECO:0000269|PubMed:12816872, ECO:0000269|PubMed:23768516}.

PRDM16 CRISPR/Cas9 KO Plasmid (h) - sc-403464 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PRDM16 HDR Plasmid (h) - sc-403464-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PRDM16 Double Nickase Plasmid (h) - sc-403464-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PRDM16 Double Nickase Plasmid (h2) - sc-403464-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PRDM16 CRISPR Activation Plasmid (h) - sc-403464-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PRDM16 CRISPR Activation Plasmid (h2) - sc-403464-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PRDM16 Lentiviral Activation Particles (h) - sc-403464-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PRDM16 Lentiviral Activation Particles (h2) - sc-403464-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PRDM16 siRNA (h) - sc-62854 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PRDM16 shRNA Plasmid (h) - sc-62854-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PRDM16 shRNA (h) Lentiviral Particles - sc-62854-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PRDM16/MEL1 RNAi - H00063976-R02 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

CompoZr® Knockout ZFN Kit - CKOZFN17374 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND17374 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

PRDM16 siRNA (Human) - CRJ1888 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

PRDM16/MEL1 RNAi - H00063976-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

shRNA set against Human Prdm16 (NM_199454.2) - SHH382216 from Creative biogene

Category siRNA
Species Reactivities Human

Human PRDM16 siRNA - orb272389 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

PRDM16 shRNA Plasmid (Human) - CHJ1888 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

PRDM16 miRNA 3'UTR clone - MiUTR4H-TG07018 from Creative biogene

Species Reactivities Human
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