PRDM16

Gene Symbol	PRDM16
Entrez Gene	63976
Alt Symbol	CMD1LL, LVNC8, MEL1, PFM13
Species	Human
Gene Type	protein-coding
Description	PR domain containing 16
Other Description	MDS1/EVI1-like gene 1|PR domain zinc finger protein 16|transcription factor MEL1
Swissprots	Q9HAZ2 Q8WYJ9 B1AJP9 B1AJP8 B1AJP7 A6NHQ8 B1WB48 Q9C0I8
Accessions	CCQ43680 EAW71449 EAW71450 EAW71451 Q9HAZ2 AB051462 BAB21766 AB078876 BAB84297 AF294278 AAG33382 AI623202 AK093853 AK094178 AK309078 BC110593 BC161614 AAI61614 BC168363 AAI68363 BQ897896 BX092842 XM_005244772 XP_005244829 XM_005244773 XP_005244830 XM_005244774 XP_005244831 XM_006710814 XP_006710877 XM_011541944 XP_011540246 XM_011541945 XP_011540247 NM_022114 NP_071397 NM_199454 NP_955533
Function	Binds DNA and functions as a transcriptional regulator. Functions in the differentiation of brown adipose tissue (BAT) which is specialized in dissipating chemical energy in the form of heat in response to cold or excess feeding while white adipose tissue (WAT) is specialized in the storage of excess energy and the control of systemic metabolism. Together with CEBPB, regulates the differentiation of myoblastic precursors into brown adipose cells. Functions also as a repressor of TGF-beta signaling. Isoform 4 may regulate granulocytes differentiation. {ECO:0000269|PubMed:12816872, ECO:0000269|PubMed:14656887, ECO:0000269|PubMed:19049980}.
Subcellular Location	Nucleus {ECO:0000269|PubMed:19049980}.
Tissue Specificity	Expressed in uterus and kidney. Expressed in both cardiomyocytes and interstitial cells. {ECO:0000269|PubMed:11050005, ECO:0000269|PubMed:12816872, ECO:0000269|PubMed:23768516}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human PRDM16 peptide - ab95842 from Abcam Category Peptide

PRDM16 Antibody Blocking Peptide - LS-E25409 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

PRDM16 Antibody Blocking Peptide - LS-E30839 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

PRDM16 Antibody Blocking Peptide - LS-E11725 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

PRDM16 Blocking Peptide - LS-E27907 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

PRDM16/MEL1 Blocking Peptide - NBP1-77096PEP from Novus Biologicals Category Peptide Prices $129.00 Sizes 50 µg Species Human

PRDM16 blocking peptide - GTX89869-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human

E.coli MEL1 protein - orb246516 from Biorbyt Category Protein Prices $340.00, $629.00, $1,003.00, $1,556.00 Sizes 50 μg, 200 μg, 500 μg, 1 mg Species Escherichia coli

Goat anti PRDM16 antibody Immunizing peptide - orb17353 from Biorbyt Category Peptide Prices $247.00 Sizes 100 μg Species Human, Mouse, Rat

PRDM16 Peptide - AC21-0237-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

PRDM16 Control Peptide - AP30689CP-N from Acris Antibodies Category Peptide Prices $135.00 Sizes 50 µg

PRDM16 Peptide - 46-216P from ProSci Category Peptide

PRDM16 Peptide - 5555P from ProSci Category Peptide Species Human

Recombinant Human PRDM16, His-tagged - PRDM16-31106TH from Creative Biomart Category Protein Source E. coli

Recombinant Saccharomyces cerevisiae Alpha-galactosidase 1(MEL1) - CSB-YP356371SAC CSB-BP356371SAC CSB-MP356371SAC from Cusabio Category Protein Source Yeast or Baculovirus or Mammalian cell

Recombinant Saccharomyces cerevisiae Alpha-galactosidase 1(MEL1) - CSB-EP356371SAC from Cusabio Category Protein Source Yeast Species Yeast

Recombinant Human PR domain zinc finger protein 16(PRDM16) ,partial - CSB-YP872534HU CSB-EP872534HU CSB-BP872534HU CSB-MP872534HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

PRDM16 (transcript variant 1) - TP314026 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

PR domain zinc finger protein 16 (PRDM16), partial, Recombinant Protein - MBS1300975 from MyBioSource Category Protein Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

PRDM16/MEL1, Peptide - MBS425044 from MyBioSource Category Peptide Prices $175.00 Sizes 100 µg Species Human

Recombinant Human PRDM16 protein, MYC/DDK-tagged - PRDM16-8327H from Creative Biomart Category Protein Source HEK293 Species Human

PRDM16-Blocking-Peptide-Center - BP20831c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

PRDM16-Antibody-N-term-Blocking-peptide - BP1216a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

PRDM16 Peptide, Human - M34GP12351H from Creative Peptides Category Peptide Source Synthetic. Species Human

MEL1 Recombinant Protein (OPCA02110) - OPCA02110 from Aviva Systems Biology Category Protein Prices $250.00 Sizes 50 µg Source Yeast

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