CREB3L2

Gene Symbol CREB3L2
Entrez Gene 64764
Alt Symbol BBF2H7
Species Human
Gene Type protein-coding
Description cAMP responsive element binding protein 3-like 2
Other Description B-ZIB transcription factor|BBF2 human homolog on chromosome 7|FUS/BBF2H7 protein|TCAG_1951439|basic transcription factor 2|cAMP-responsive element-binding protein 3-like protein 2|cyclic AMP-responsive element-binding protein 3-like protein 2
Swissprots Q6ZMR6 Q6P454 Q70SY1
Accessions EAL24050 EAW83878 EAW83879 EAW83880 Q70SY1 AJ549092 CAD79342 AJ549387 CAD79347 AK131517 BAD18659 AK293048 BAF85737 AL080209 BC015585 BC046181 AAH46181 BC063666 AAH63666 BC110813 AAI10814 BC131723 AAI31724 BQ711676 BX648300 BX649143 CN394705 CR749563 CAH18360 EU446520 ABZ92049 XM_005250541 XP_005250598 XM_011516492 XP_011514794 NM_001253775 NP_001240704 NM_194071 NP_919047
Function Transcriptional activator which is processed and activated during endoplasmic reticulum stress late phase. Binds to the cAMP response element (CRE) and activates transcription through CRE. Regulates the transcription of unfolded protein response target genes, preventing accumulation of unfolded proteins in damaged neurons. Also regulates the expression of SEC23A, accelerating protein trafficking from the ER to the Golgi thereby playing a key role in chondrocyte differentiation and formation of epiphyseal cartilage (By similarity). {ECO:0000250}.
Subcellular Location Endoplasmic reticulum membrane {ECO:0000269|PubMed:17178827}; Single-pass type II membrane protein {ECO:0000269|PubMed:17178827}.
Tissue Specificity Widely expressed with highest levels in placenta, lung, spleen and intestine, and lowest levels in heart, brain, skeletal muscle, thymus, colon and leukocytes. In fetal tissues, the weakest expression is detected in brain and heart. {ECO:0000269|PubMed:12915480}.
Top Pathways cGMP-PKG signaling pathway, Huntington's disease, Glucagon signaling pathway, Prostate cancer, PI3K-Akt signaling pathway

CREB3L2 (C-16) - sc-69369 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
CREB3L2 (C-16): sc-69369. Western blot analysis of CREB3L2 expression in non-transfected 293T: sc-117752 (A) and human CREB3L2 transfected 293T: sc-370243 (B) whole cell lysates.

CREB3L2 (H-133) - sc-366044 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
CREB3L2 (H-133): sc-366044. Western blot analysis of CREB3L2 expression in HeLa (A) and THP-1 (B) whole cell lysates and mouse testis tissue extract (C).

CREB3L2 (P-20) - sc-69372 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
CREB3L2 (P-20): sc-69372. Western blot analysis of CREB3L2 expression in Jurkat (A), HeLa (B) and THP-1 (C) whole cell lysates.

CREB3L2 (F-23) - sc-133483 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal
CREB3L2 (F-23): sc-133483. Immunoperoxidase staining of formalin-fixed, paraffin-embedded human kidney tissue showing cytoplasmic localization.

Anti-CREB3L2 antibody - ab102989 from Abcam

Prices $380.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-CREB3L2 antibody (ab102989) at 1/100 dilution + HeLa cell lysate at 35 µg

Anti-CREB3L2 antibody - ab76856 from Abcam

Prices $380.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Anti-CREB3L2 antibody (ab76856) at 5 µg/ml + recombinant tagged fragment (immunogen) at 0.2 µg/mlSecondaryGoat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/5000 dilutiondeveloped using the ECL technique

Anti-CREB3L2 antibody - ab136017 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-CREB3L2 antibody (ab136017) at 1/500 dilution + 293 cell lysate at 30 µg

Anti-CREB3L2 / BBF2H7 Antibody (aa15-28) IHC-plus™ - LS-B10572 from LifeSpan Bioscience

Host Goat
Clonality Polyclonal
Anti-CREB3L2 / BBF2H7 antibody IHC staining of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B10572 concentration 5 ug/ml.

Anti-CREB3L2 / BBF2H7 Antibody (aa491-520, AP) - LS-C234224 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-CREB3L2 / BBF2H7 Antibody (aa491-520, APC) - LS-C234225 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-CREB3L2 / BBF2H7 Antibody (aa491-520, Biotin) - LS-C234226 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-CREB3L2 / BBF2H7 Antibody (aa491-520, FITC) - LS-C234227 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-CREB3L2 / BBF2H7 Antibody (aa491-520, Azide-free, HRP) - LS-C249752 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-CREB3L2 / BBF2H7 Antibody (aa491-520, PE) - LS-C234229 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-CREB3L2 / BBF2H7 Antibody (aa421-519) - LS-C307083 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal

Anti-CREB3L2 / BBF2H7 Antibody (aa491-520) - LS-C320586 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-CREB3L2 / BBF2H7 Antibody (aa250-299) - LS-C291832 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-CREB3L2 / BBF2H7 Antibody (aa34-72) - LS-C31226 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
CREB3L2 antibody LS-C31226 was used in IHC to stain formalin-fixed, paraffin-embedded human kidney.

Anti-CREB3L2 / BBF2H7 Antibody (aa491-520) - LS-C167026 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
CREB3L2 Antibody western blot of human placenta and mouse lung tissue lysates (35 ug/lane). The CREB3L2 antibody detected the CREB3L2 protein (arrow).

CREB3L2 Antibody - NBP1-88697 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry: CREB3L2 Antibody [NBP1-88697] - Staining of human placenta shows strong nuclear and cytoplasmic positivity in trophoblastic cells.

CREB3L2 Antibody (1B8) - H00064764-M03 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 1B8
Sandwich ELISA: CREB3L2 Antibody (1B8) [H00064764-M03] - Detection limit for recombinant GST tagged CREB3L2 is 0.1 ng/ml as a capture antibody.

Monoclonal Anti-CREB3L2 antibody produced in mouse - SAB1403353 from Sigma-Aldrich

Prices $347.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 1B8
<B>Immunoblotting</B><BR/>Monoclonal Anti-CREB3L2: <B>Cat. No. SAB1403353</B>: Antibody concentration: 1 μg/mL. Specific band of ~36.9 kDa using immunogen protein lysate.

Anti-CREB3L2 antibody produced in rabbit - AV34673 from Sigma-Aldrich

Prices $267.50, $267.50
Sizes 100 µg, 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-CREB3L2: <B>Cat. No. AV34673</B>: Immunohistochemistry of CREB3L2 in Human Kidney tissue with CREB3L2 antibody at 4-8 μg/mL.

Anti-CREB3L2 antibody produced in rabbit - HPA015068 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-CREB3L2: <B>Cat. No. HPA015068</B>: Immunoperoxidase staining of formalin-fixed, paraffin-embedded human placenta shows strong nuclear and cytoplasmic positivity in trophoblastic cells.

CREB3L2 antibody - N-terminal region (ARP34673_T100) - ARP34673_T100 from Aviva Systems Biology

Prices $229.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
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