CREB3L2

Gene Symbol	CREB3L2
Entrez Gene	64764
Alt Symbol	BBF2H7
Species	Human
Gene Type	protein-coding
Description	cAMP responsive element binding protein 3-like 2
Other Description	B-ZIB transcription factor|BBF2 human homolog on chromosome 7|FUS/BBF2H7 protein|TCAG_1951439|basic transcription factor 2|cAMP-responsive element-binding protein 3-like protein 2|cyclic AMP-responsive element-binding protein 3-like protein 2
Swissprots	Q6ZMR6 Q6P454 Q70SY1
Accessions	EAL24050 EAW83878 EAW83879 EAW83880 Q70SY1 AJ549092 CAD79342 AJ549387 CAD79347 AK131517 BAD18659 AK293048 BAF85737 AL080209 BC015585 BC046181 AAH46181 BC063666 AAH63666 BC110813 AAI10814 BC131723 AAI31724 BQ711676 BX648300 BX649143 CN394705 CR749563 CAH18360 EU446520 ABZ92049 XM_005250541 XP_005250598 XM_011516492 XP_011514794 NM_001253775 NP_001240704 NM_194071 NP_919047
Function	Transcriptional activator which is processed and activated during endoplasmic reticulum stress late phase. Binds to the cAMP response element (CRE) and activates transcription through CRE. Regulates the transcription of unfolded protein response target genes, preventing accumulation of unfolded proteins in damaged neurons. Also regulates the expression of SEC23A, accelerating protein trafficking from the ER to the Golgi thereby playing a key role in chondrocyte differentiation and formation of epiphyseal cartilage (By similarity). {ECO:0000250}.
Subcellular Location	Endoplasmic reticulum membrane {ECO:0000269|PubMed:17178827}; Single-pass type II membrane protein {ECO:0000269|PubMed:17178827}.
Tissue Specificity	Widely expressed with highest levels in placenta, lung, spleen and intestine, and lowest levels in heart, brain, skeletal muscle, thymus, colon and leukocytes. In fetal tissues, the weakest expression is detected in brain and heart. {ECO:0000269|PubMed:12915480}.
Top Pathways	cGMP-PKG signaling pathway, Huntington's disease, Glucagon signaling pathway, Prostate cancer, PI3K-Akt signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human CREB3L2 full length protein - ab163871 from Abcam Category Protein Source Wheat germ Species Human

Human CREB3L2 protein fragment - ab163872 from Abcam Category Protein Source Wheat germ Species Human

Human CREB3L2 protein fragment - ab202158 from Abcam Category Protein Source E. coli Species Human

CREB3L2 / BBF2H7 Antibody Blocking Peptide - LS-E12329 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

CREB3L2 / BBF2H7 Antibody Blocking Peptide - LS-E10247 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

CREB3L2 Partial Recombinant Protein - H00064764-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

CREB3L2 Recombinant Protein - H00064764-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

CREB3L2-Antibody-C-term-Blocking-Peptide - BP9654b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

CREB3L2 protein (His tag) - 80R-4055 from Fitzgerald Category Protein Prices $275.00 Sizes 20 µg Source E.coli

CREB3L2 Blocking Peptide - abx063954 from Abbexa Category Peptide Species Human

CREB3L2 Peptide - AC21-2986-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

CREB3L2 (1-378, His-tag) - AR51740PU-N from Acris Antibodies Category Protein Prices $790.00 Sizes 100 µg Source E. coli Species Human

CREB3L2 (1-378, His-tag) - AR51740PU-S from Acris Antibodies Category Protein Prices $340.00 Sizes 20 µg Source E. coli Species Human

CREB3L2 - H00064764-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

CREB3L2 - H00064764-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

CREB3L2 - H00064764-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

CREB3L2 - H00064764-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

CREB3L2 fusion protein - Ag5973 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

CREB3L2 fusion protein - Ag6068 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

Recombinant Human CREB3L2, GST-tagged - CREB3L2-11561H from Creative Biomart Category Protein Source E.coli Species Human

CREB3L2 Blocking Peptide - CBP2760 from Cohesion Biosciences Category Peptide Prices $100.00, $300.00 Sizes 1 mg, 5 mg Species Human

Recombinant Human Cyclic AMP-responsive element-binding protein 3-like protein 2(CREB3L2) - CSB-YP754617HU CSB-EP754617HU CSB-BP754617HU CSB-MP754617HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

CREB3L2, 1-378aa, Human, His tag, E.coli - ATGP2920 from ATGen Category Protein Prices $80.00, $240.00, $720.00 Sizes 4 µg, 20 µg, 100 µg Species Human

CREB3L2 Protein - abx163584 from Abbexa Category Protein Species Human, Rat

CREB3L2, Peptide - MBS428097 from MyBioSource Category Peptide Prices $175.00 Sizes 100 µg Species Human

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