CREB3L2

Gene Symbol CREB3L2
Entrez Gene 64764
Alt Symbol BBF2H7
Species Human
Gene Type protein-coding
Description cAMP responsive element binding protein 3-like 2
Other Description B-ZIB transcription factor|BBF2 human homolog on chromosome 7|FUS/BBF2H7 protein|TCAG_1951439|basic transcription factor 2|cAMP-responsive element-binding protein 3-like protein 2|cyclic AMP-responsive element-binding protein 3-like protein 2
Swissprots Q6ZMR6 Q6P454 Q70SY1
Accessions EAL24050 EAW83878 EAW83879 EAW83880 Q70SY1 AJ549092 CAD79342 AJ549387 CAD79347 AK131517 BAD18659 AK293048 BAF85737 AL080209 BC015585 BC046181 AAH46181 BC063666 AAH63666 BC110813 AAI10814 BC131723 AAI31724 BQ711676 BX648300 BX649143 CN394705 CR749563 CAH18360 EU446520 ABZ92049 XM_005250541 XP_005250598 XM_011516492 XP_011514794 NM_001253775 NP_001240704 NM_194071 NP_919047
Function Transcriptional activator which is processed and activated during endoplasmic reticulum stress late phase. Binds to the cAMP response element (CRE) and activates transcription through CRE. Regulates the transcription of unfolded protein response target genes, preventing accumulation of unfolded proteins in damaged neurons. Also regulates the expression of SEC23A, accelerating protein trafficking from the ER to the Golgi thereby playing a key role in chondrocyte differentiation and formation of epiphyseal cartilage (By similarity). {ECO:0000250}.
Subcellular Location Endoplasmic reticulum membrane {ECO:0000269|PubMed:17178827}; Single-pass type II membrane protein {ECO:0000269|PubMed:17178827}.
Tissue Specificity Widely expressed with highest levels in placenta, lung, spleen and intestine, and lowest levels in heart, brain, skeletal muscle, thymus, colon and leukocytes. In fetal tissues, the weakest expression is detected in brain and heart. {ECO:0000269|PubMed:12915480}.
Top Pathways cGMP-PKG signaling pathway, Huntington's disease, Glucagon signaling pathway, Prostate cancer, PI3K-Akt signaling pathway

CREB3L2 - MBS1271277 from MyBioSource

Prices $175.00
Sizes 10ug plasmid + 200ul glycerol stock
Species Human
Accession BC063666

Human CREB3L2 ORF Clone(NM_194071.3) - CDCL159711 from Creative Biomart

Species Human
Accession NM_194071.3

Human CREB3L2 Gene cDNA Clone (full-length ORF Clone) - HG15245-G from Sino Biological

Species Human
Accession BC063666

Human CREB3L2 natural ORF mammalian expression plasmid, C-GFPSpark tag - HG15245-ACG from Sino Biological

Species Human
Accession BC063666

Human CREB3L2 natural ORF mammalian expression plasmid, N-Flag tag - HG15245-NF from Sino Biological

Species Human
Accession BC063666

Human CREB3L2 ORF clone (NM_001253775.1) - CDCR050504 from Creative biogene

Species Human

Human CREB3L2 ORF Clone (BC063666) - CDCS409991 from Creative biogene

Species Human
Accession Q70SY1

Human CREB3L2 ORF clone (BC063666) - CDCB158289 from Creative biogene

Species Human

Human Basic transcription factor 2 Gene - orb142651 from Biorbyt

Prices $264.00
Sizes 10 μg
Species Human
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