CDK13

Gene Symbol	CDK13
Entrez Gene	8621
Alt Symbol	CDC2L, CDC2L5, CHED, hCDK13
Species	Human
Gene Type	protein-coding
Description	cyclin-dependent kinase 13
Other Description	CDC2-related protein kinase 5|cell division cycle 2-like protein kinase 5|cell division protein kinase 13|cholinesterase-related cell division controller
Swissprots	Q9H4A0 Q75MH5 Q9UDR4 Q96JN4 Q14004 Q6DKQ9 Q9H4A1 Q53G78 Q75MH4
Accessions	AAD54514 AAS07490 AAS07491 AAT74623 EAW94128 EAW94129 EAW94130 EAW94131 EAW94132 EAW94133 Q14004 AB058694 BAB47420 AJ297709 CAC10400 AJ297710 CAC10401 AK025500 AK092534 AK130653 AK223053 BAD96773 BC001274 AAH01274 BC080601 BC168380 AAI68380 BF707421 BM699295 BM727913 BU686489 BX647326 CR748837 M80629 AAA58424 XM_011515597 XP_011513899 XM_011515598 XP_011513900 NM_003718 NP_003709 NM_031267 NP_112557
Function	Cyclin-dependent kinase which displays CTD kinase activity and is required for RNA splicing. Has CTD kinase activity by hyperphosphorylating the C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit RPB1, thereby acting as a key regulator of transcription elongation. Required for RNA splicing, probably by phosphorylating SRSF1/SF2. Required during hematopoiesis. In case of infection by HIV-1 virus, interacts with HIV-1 Tat protein acetylated at 'Lys-50' and 'Lys- 51', thereby increasing HIV-1 mRNA splicing and promoting the production of the doubly spliced HIV-1 protein Nef. {ECO:0000269|PubMed:16721827, ECO:0000269|PubMed:1731328, ECO:0000269|PubMed:18480452, ECO:0000269|PubMed:20952539}.
Subcellular Location	Nucleus speckle {ECO:0000269|PubMed:16721827}.
Tissue Specificity	Expressed in fetal brain, liver, muscle and in adult brain. Also expressed in neuroblastoma and glioblastoma tumors.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Cdc2L5 (S-19) - sc-79895 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

Cdc2L5 (ZZ08) - sc-81837 from Santa Cruz Biotechnology Prices $295.00 Sizes 100 µg/ml Host Mouse Clonality Monoclonal

Anti-CDC2L5 antibody - ab58309 from Abcam Prices $370.00 Sizes 100 µg Host Mouse Clonality Monoclonal

Anti-CDK13 / CDC2L5 Antibody (clone 1B3-1B11) - LS-C306861 from LifeSpan Bioscience Host Mouse Clonality Monoclonal Clone 1B3-1B11

Anti-CDK13 / CDC2L5 Antibody (aa1-30) - LS-C320229 from LifeSpan Bioscience Prices $435.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-CDK13 / CDC2L5 Antibody (aa281-310) - LS-C329350 from LifeSpan Bioscience Prices $345.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-CDK13 / CDC2L5 Antibody (aa281-310, Biotin) - LS-C213225 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-CDK13 / CDC2L5 Antibody (aa1125-1175) - LS-C288253 from LifeSpan Bioscience Prices $375.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-CDK13 / CDC2L5 Antibody (aa281-310) - LS-C164325 from LifeSpan Bioscience Prices $295.00 Sizes 400 µl Host Rabbit Clonality Polyclonal

Anti-CDK13 / CDC2L5 Antibody (aa1-30, AP) - LS-C213204 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-CDK13 / CDC2L5 Antibody (aa1-325, clone 10B2175, Azide-free) - LS-C183507 from LifeSpan Bioscience Prices $485.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone 10B2175

Anti-CDK13 / CDC2L5 Antibody (aa1-30, APC) - LS-C213206 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-CDK13 / CDC2L5 Antibody (aa1-30, Biotin) - LS-C213208 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-CDK13 / CDC2L5 Antibody (aa1-30, Azide-free, HRP) - LS-C213210 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-CDK13 / CDC2L5 Antibody (aa281-310, AP) - LS-C213223 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-CDK13 / CDC2L5 Antibody (aa1-30, FITC) - LS-C213209 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-CDK13 / CDC2L5 Antibody (aa1-30, PE) - LS-C213211 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-CDK13 / CDC2L5 Antibody (aa281-310, APC) - LS-C213224 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-CDK13 / CDC2L5 Antibody (aa281-310, FITC) - LS-C213227 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-CDK13 / CDC2L5 Antibody (aa281-310, Azide-free, HRP) - LS-C213228 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-CDK13 / CDC2L5 Antibody (aa281-310, PE) - LS-C213229 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

CDC2L5 Antibody - NB100-68268 from Novus Biologicals Prices $359.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

CDC2L5 Antibody - NBP2-34123 from Novus Biologicals Prices $419.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

CDC2L5 Antibody (1B3-1B11) - H00008621-M01 from Novus Biologicals Prices $359.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone 1B3-1B11

CDC2L5 Antibody (3G1) - H00008621-M02 from Novus Biologicals Prices $359.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone 3G1

Search more