SCIN

Gene Symbol	SCIN
Entrez Gene	85477
Alt Symbol	-
Species	Human
Gene Type	protein-coding
Description	scinderin
Other Description	adseverin
Swissprots	A8K2U8 Q96PY2 Q96JC7 Q9Y6U3 Q8WU97 Q8NBZ6
Accessions	AAD15423 AAS07450 EAW93645 EAW93646 EAW93647 EAW93648 Q9Y6U3 AB067492 BAB67798 AF276507 AAK60494 AK027778 BAB55361 AK075123 BAC11416 AK075198 BAC11465 AK290363 BAF83052 BC021090 AAH21090 CA447429 CA448540 DB196860 DQ892033 ABM82959 DQ895224 ABM86150 XR_926951 NM_001112706 NP_001106177 NM_033128 NP_149119
Function	Ca(2+)-dependent actin filament-severing protein that is presumed to have a regulatory function in exocytosis by affecting the organization of the microfilament network underneath the plasma membrane. In vitro, also has barbed end capping and nucleating activities in the presence of Ca(2+). Regulates chondrocyte proliferation and differentiation. MAP kinases p38 and ERK1/2 mediate the adseverin-induced accelerated differentiation of non-hypertrophic chondrocytes (By similarity). {ECO:0000250}.
Subcellular Location	Cytoplasm, cytoskeleton.
Top Pathways	Fc gamma R-mediated phagocytosis, Viral carcinogenesis, Regulation of actin cytoskeleton

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human SCIN full length protein - ab164766 from Abcam Category Protein Source Wheat germ Species Human

Recombinant Human SCIN Protein - H00085477-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

SCIN-Antibody-N-term-Blocking-Peptide - BP9945a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

SCIN - H00085477-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

SCIN - H00085477-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

SCIN fusion protein - Ag2168 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

Recombinant Human SCIN, GST-tagged - SCIN-2533H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human Adseverin(SCIN) - CSB-YP897320HU CSB-EP897320HU CSB-BP897320HU CSB-MP897320HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

ADSL - MBS1427097 from MyBioSource Category Protein Prices $2,610.00, $2,610.00, $3,030.00, $3,030.00 Sizes 1 mg (E Coli Derived), 100 µg (Baculovirus Derived), 1 mg (Yeast Derived), 100 µg (Mammalian Cell Derived) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

SCIN (transcript variant 2) - TP305801 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

SCIN Recombinant Protein Antigen - NBP1-89230PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

SCIN Recombinant Protein Antigen - NBP1-89229PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

SCIN Peptide, Human - M34GP13855H from Creative Peptides Category Peptide Source Synthetic. Species Human

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