SCIN

Gene Symbol SCIN
Entrez Gene 85477
Alt Symbol -
Species Human
Gene Type protein-coding
Description scinderin
Other Description adseverin
Swissprots A8K2U8 Q96PY2 Q96JC7 Q9Y6U3 Q8WU97 Q8NBZ6
Accessions AAD15423 AAS07450 EAW93645 EAW93646 EAW93647 EAW93648 Q9Y6U3 AB067492 BAB67798 AF276507 AAK60494 AK027778 BAB55361 AK075123 BAC11416 AK075198 BAC11465 AK290363 BAF83052 BC021090 AAH21090 CA447429 CA448540 DB196860 DQ892033 ABM82959 DQ895224 ABM86150 XR_926951 NM_001112706 NP_001106177 NM_033128 NP_149119
Function Ca(2+)-dependent actin filament-severing protein that is presumed to have a regulatory function in exocytosis by affecting the organization of the microfilament network underneath the plasma membrane. In vitro, also has barbed end capping and nucleating activities in the presence of Ca(2+). Regulates chondrocyte proliferation and differentiation. MAP kinases p38 and ERK1/2 mediate the adseverin-induced accelerated differentiation of non-hypertrophic chondrocytes (By similarity). {ECO:0000250}.
Subcellular Location Cytoplasm, cytoskeleton.
Top Pathways Fc gamma R-mediated phagocytosis, Viral carcinogenesis, Regulation of actin cytoskeleton

adseverin CRISPR/Cas9 KO Plasmid (h) - sc-403799 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

adseverin HDR Plasmid (h) - sc-403799-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

adseverin Double Nickase Plasmid (h) - sc-403799-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

adseverin Double Nickase Plasmid (h2) - sc-403799-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

adseverin CRISPR Activation Plasmid (h) - sc-403799-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

adseverin CRISPR Activation Plasmid (h2) - sc-403799-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

adseverin Lentiviral Activation Particles (h) - sc-403799-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

adseverin Lentiviral Activation Particles (h2) - sc-403799-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

adseverin siRNA (h) - sc-72455 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

adseverin shRNA Plasmid (h) - sc-72455-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

adseverin shRNA (h) Lentiviral Particles - sc-72455-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU133451 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN18942 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND18942 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR07126 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr07126

SCIN siRNA (Human) - CRJ3834 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

SCIN - MBS8210468 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human SCIN (NM_033128.3) - SHH402676 from Creative biogene

Category siRNA
Species Reactivities Human

Human SCIN siRNA - orb274335 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

SCIN shRNA Plasmid (Human) - CHJ3834 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

SCIN miRNA 3'UTR clone - MiUTR3H-12885 from Creative biogene

Species Reactivities Human

SCIN miRNA 3'UTR clone - MiUTR3H-12886 from Creative biogene

Species Reactivities Human
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