SCIN

Gene Symbol SCIN
Entrez Gene 85477
Alt Symbol -
Species Human
Gene Type protein-coding
Description scinderin
Other Description adseverin
Swissprots A8K2U8 Q96PY2 Q96JC7 Q9Y6U3 Q8WU97 Q8NBZ6
Accessions AAD15423 AAS07450 EAW93645 EAW93646 EAW93647 EAW93648 Q9Y6U3 AB067492 BAB67798 AF276507 AAK60494 AK027778 BAB55361 AK075123 BAC11416 AK075198 BAC11465 AK290363 BAF83052 BC021090 AAH21090 CA447429 CA448540 DB196860 DQ892033 ABM82959 DQ895224 ABM86150 XR_926951 NM_001112706 NP_001106177 NM_033128 NP_149119
Function Ca(2+)-dependent actin filament-severing protein that is presumed to have a regulatory function in exocytosis by affecting the organization of the microfilament network underneath the plasma membrane. In vitro, also has barbed end capping and nucleating activities in the presence of Ca(2+). Regulates chondrocyte proliferation and differentiation. MAP kinases p38 and ERK1/2 mediate the adseverin-induced accelerated differentiation of non-hypertrophic chondrocytes (By similarity). {ECO:0000250}.
Subcellular Location Cytoplasm, cytoskeleton.
Top Pathways Fc gamma R-mediated phagocytosis, Viral carcinogenesis, Regulation of actin cytoskeleton

adseverin (C-2) - sc-376136 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
adseverin (C-2): sc-376136. Western blot analysis of adseverin expression in non-transfected: sc-117752 (A) and human adseverin transfected: sc-170369 (B) 293T whole cell lysates.

adseverin (N-17) - sc-79835 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
adseverin (N-17): sc-79835. Western blot analysis of adseverin expression in non-transfected: sc-117752 (A) and human adseverin transfected: sc-170369 (B) 293T whole cell lysates.

Anti-SCIN [EPR16309] antibody - ab191396 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR16309
All lanes : Anti-SCIN [EPR16309] antibody (ab191396) at 1/5000 dilutionLane 1 : Human placenta tissue lysateLane 2 : Human fetal kidney tissue lysateLysates/proteins at 10 µg per lane.SecondaryAnti-Rabbit IgG (HRP), specific to the non-reduced form of IgG at 1/1000 dilution

Anti-SCIN antibody - ab96105 from Abcam

Prices $304.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Anti-SCIN antibody (ab96105) at 1/1000 dilution + HepG2 cell lysate at 30 µg

Anti-SCIN antibody [EPR16310] - C-terminal - ab199723 from Abcam

Prices $347.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR16310
All lanes : Anti-SCIN antibody [EPR16310] - C-terminal (ab199723) at 1/10000 dilutionLane 1 : Human fetal kidney lysateLane 2 : HEK293 (Human embryonic kidney) whole cell lysateLysates/proteins at 20 µg per lane.SecondaryAnti-Rabbit IgG (HRP), specific to the non-reduced form of IgG at 1/1000 dilution

Anti-SCIN Antibody (aa281-585) - LS-C186278 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Confocal immunofluorescence analysis (Olympus FV10i) of methanol-fixed HeLa using SCIN antibody (Green) at 1:500 dilution. Alpha-tubulin filaments were labeled with alpha-tubulin antibody (Red) at 1:2000.

SCIN Antibody - NBP1-89230 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: SCIN Antibody [NBP1-89230] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11<br/>Lane 2: Human cell line RT-4

SCIN Antibody - NBP1-89231 from Novus Biologicals

Host Rabbit
Clonality Polyclonal
Western Blot: SCIN Antibody [NBP1-89231] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11<br/>Lane 2: Human cell line RT-4

SCIN Antibody - NBP1-89229 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

SCIN Antibody - NBP1-31721 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: SCIN Antibody [NBP1-31721] - Sample (30 ug of whole cell lysate) A: Hep G2 7. 5% SDS PAGE; antibody diluted at 1:1000.

SCIN Antibody - H00085477-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Western Blot: SCIN Antibody [H00085477-B01P] - Analysis of SCIN expression in human pancreas.

SCIN Antibody - H00085477-D01P from Novus Biologicals

Prices $399.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: SCIN Antibody [H00085477-D01P] - Analysis of SCIN expression in mouse kidney.

Anti-SCIN antibody produced in rabbit - SAB1411537 from Sigma-Aldrich

Prices $347.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-SCIN: <B>Cat. No. SAB1411537</B>: Antibody concentration: 1-5 μg/mL. Specific band of ~80.5 kDa using human kidney lysate.

Anti-SCIN antibody produced in mouse - SAB1400756 from Sigma-Aldrich

Prices $347.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Polyclonal Anti-SCIN, antibody produced in mouse, purified immunoglobulin: <B>Cat. No. SAB1400756</B>: Antibody concentration: 1.0 ~ 5.0 μg/mL. Specific band of ~80.489 kDa using human kidney lysate.

Anti-SCIN antibody produced in rabbit - HPA024264 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-SCIN: <B>Cat. No. HPA024264</B>: Immunohistochemical staining of human kidney shows strong cytoplasmic and membranous positivity in a subset of tubules.

ADSV Antibody - middle region (ARP75834_P050) - ARP75834_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

SCIN antibody - 70R-13502 from Fitzgerald

Prices $395.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

SCIN antibody - 70R-20107 from Fitzgerald

Prices $375.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal

SCIN Polyclonal Antibody - A5078 from ABclonal

Prices $200.00, $480.00
Sizes 50 µg, 200 µg
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts of PC-3 cell line, using SCIN antibody.

Scinderin antibody - orb69817 from Biorbyt

Prices $723.00
Sizes 100 μl
Host Rabbit
Clonality Polyclonal
Western Blot analysis of A:HepG2 whole cell lysate using Scinderin antibody

SCIN antibody (OAGA00980) - OAGA00980 from Aviva Systems Biology

Prices $340.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

SCIN Antibody - abx003882 from Abbexa

Host Rabbit
Clonality Polyclonal

SCIN antibody - 11579-1-AP from Acris Antibodies

Prices $270.00
Sizes 150 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemical of  paraffin-embedded human pancreas cancer using 11579-1-AP(SCIN antibody) at dilution of 1:50 (under 10x lens)

SCIN antibody - H00085477-B01P from Acris Antibodies

Prices $360.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
SCIN MaxPab polyclonal antibody. Western Blot analysis of SCIN expression in human pancreas.

SCIN antibody - H00085477-D01P from Acris Antibodies

Prices $390.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
SCIN MaxPab rabbit polyclonal antibody. Western Blot analysis of SCIN expression in mouse kidney.
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