APOBEC3D

Gene Symbol APOBEC3D
Entrez Gene 140564
Alt Symbol A3D, APOBEC3DE, APOBEC3E, ARP6
Species Human
Gene Type protein-coding
Description apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3D
Other Description DNA dC->dU-editing enzyme APOBEC-3D|apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3E pseudogene|probable DNA dC->dU-editing enzyme APOBEC-3D
Swissprots Q96AK3 Q5JZ91 Q7Z2N6
Accessions EAW60285 EAW60286 Q96AK3 BC017022 BC148619 AAI48620 BC153185 AAI53186 BE888971 BF832090 BM917407 BX340829 CR456396 CAG30282 CU012954 CAK54385 CU013242 CAK54684 DA287097 DB121958 EU527884 ACB32248 XM_005261337 XP_005261394 XM_006724139 XP_006724202 XM_011529892 XP_011528194 NM_152426 NP_689639
Function DNA deaminase (cytidine deaminase) which acts as an inhibitor of retrovirus replication and retrotransposon mobility via deaminase-dependent and -independent mechanisms. Exhibits antiviral activity against vif-deficient HIV-1. After the penetration of retroviral nucleocapsids into target cells of infection and the initiation of reverse transcription, it can induce the conversion of cytosine to uracil in the minus-sense single-strand viral DNA, leading to G-to-A hypermutations in the subsequent plus-strand viral DNA. The resultant detrimental levels of mutations in the proviral genome, along with a deamination- independent mechanism that works prior to the proviral integration, together exert efficient antiretroviral effects in infected target cells. Selectively targets single-stranded DNA and does not deaminate double-stranded DNA or single-or double- stranded RNA. May inhibit the mobility of LTR and non-LTR retrotransposons. {ECO:0000269|PubMed:12859895, ECO:0000269|PubMed:20062055, E
Subcellular Location Cytoplasm. Cytoplasm, P-body.
Tissue Specificity Expressed in lymphoid organs. Also detected in non-lymphoid tissues including lung. {ECO:0000269|PubMed:20308164}.

APOBEC3D/F (K-16) - sc-46735 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
APOBEC3D/F (K-16): sc-46735. Western blot analysis of APOBEC3D/F expression in MCF7 (A), Hep G2 (B) and A549 (C) whole cell lysates.

Anti-APOBEC3D + APOBEC3F antibody - ab74205 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemistry analysis of paraffin-embedded human placenta tissue using 1/50 ab74205.Left image: no pre-treatment.Right image: pre-treatment with immunizing peptide.

Anti-APOBEC3D antibody - ab105869 from Abcam

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-APOBEC3D antibody (ab105869) at 0.25 µg/ml + HepG2 cell lysate at 10 µg

Anti-APOBEC3D antibody - ab115021 from Abcam

Prices $370.00
Sizes 200 µl
Host Goat
Clonality Polyclonal
Anti-APOBEC3D antibody (ab115021) at 0.3 µg/ml + A549 lysate (in RIPA buffer) at 35 µgdeveloped using the ECL technique

Anti-APOBEC3D antibody - C-terminal - ab186888 from Abcam

Host Rabbit
Clonality Polyclonal
Anti-APOBEC3D antibody - C-terminal (ab186888) at 1 µg/ml + Jurkat whole cell lysate at 10 µg

Anti-APOBEC3D antibody - N-terminal - ab176454 from Abcam

Host Rabbit
Clonality Polyclonal
All lanes : Anti-APOBEC3D antibody - N-terminal (ab176454) at 1/1000 dilutionLane 1 : Mouse brain total cell extractLane 2 : Mouse thymus total cell extract

Anti-APOBEC3D antibody - N-terminal - ab138634 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-APOBEC3D antibody - N-terminal (ab138634) at 1/100 dilution + Human placenta tissue lysate at 35 µg

Anti-APOBEC3D Antibody (aa46-72, AP) - LS-C232760 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-APOBEC3D Antibody (aa46-72, FITC) - LS-C232764 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-APOBEC3D Antibody (aa46-72, Biotin) - LS-C232762 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-APOBEC3D Antibody (aa46-72, APC) - LS-C232763 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-APOBEC3D Antibody (aa46-72, PE) - LS-C232765 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-APOBEC3D Antibody (aa46-72, Azide-free, HRP) - LS-C249443 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-APOBEC3D Antibody (aa45-72) - LS-C319541 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-APOBEC3D Antibody (aa46-72) - LS-C159094 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
APOBEC3D Antibody western blot of human placenta tissue lysates (35 ug/lane). The APOBEC3D antibody detected the APOBEC3D protein (arrow).

Anti-APOBEC3D Antibody (aa61-74) - LS-C139782 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE)

APOBEC3D Antibody - NBP1-57440 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: APOBEC3D Antibody [NBP1-57440] - HepG2 cell lysate, Antibody Titration: 0.2-1 ug/ml

APOBEC3F Antibody - NBP1-56153 from Novus Biologicals

Prices $229.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western Blot: APOBEC3F Antibody [NBP1-56153] - Analysis of extracts from COS7/MCF-7 cells, using APOBEC3F Antibody. The lane on the right is treated with the synthesized peptide.

Anti-APOBEC3D antibody produced in goat - SAB2501777 from Sigma-Aldrich

Prices $376.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-APOBEC3D: <B>Cat. No. SAB2501777</B>: (0.3 μg/mL) staining of A549 lysate (35 μg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Anti-APOBEC3D antibody produced in rabbit - AV41147 from Sigma-Aldrich

Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-APOBEC3D: <B>Cat. No. AV41147</B>: Immunohistochemistry of APOBEC3D in Human Kidney tissue with APOBEC3D antibody at 4-8 μg/mL.

Anti-APOBEC3D antibody produced in rabbit - HPA055116 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-APOBEC3D: <B>Cat. No. HPA055116</B>: Immunohistochemical staining of human bone marrow shows strong cytoplasmic positivity in hematopoietic cells.

APOBEC3D Antibody - C-terminal region (ARP34347_P050) - ARP34347_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

APOBEC3D antibody - N-terminal region (ARP41147_P050) - ARP41147_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

APOBEC3D-Antibody-N-term - AP18763a from Abgent, a WuXi AppTec company

Prices $99.00, $295.00
Sizes 80 µl, 400 µl
Host Rabbit
Clonality Polyclonal
APOBEC3D Antibody (N-term)(Cat. #AP18763a) western blot analysis in human placenta tissue lysates (35ug/lane).This demonstrates the APOBEC3D antibody detected the APOBEC3D protein (arrow).

APOBEC3D-aa61-74-Antibody-internal-region - AF3537a from Abgent, a WuXi AppTec company

Prices $335.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
AF3537a (0.3 µg/ml) staining of A549 lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
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