APOBEC3D

Gene Symbol	APOBEC3D
Entrez Gene	140564
Alt Symbol	A3D, APOBEC3DE, APOBEC3E, ARP6
Species	Human
Gene Type	protein-coding
Description	apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3D
Other Description	DNA dC->dU-editing enzyme APOBEC-3D|apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3E pseudogene|probable DNA dC->dU-editing enzyme APOBEC-3D
Swissprots	Q96AK3 Q5JZ91 Q7Z2N6
Accessions	EAW60285 EAW60286 Q96AK3 BC017022 BC148619 AAI48620 BC153185 AAI53186 BE888971 BF832090 BM917407 BX340829 CR456396 CAG30282 CU012954 CAK54385 CU013242 CAK54684 DA287097 DB121958 EU527884 ACB32248 XM_005261337 XP_005261394 XM_006724139 XP_006724202 XM_011529892 XP_011528194 NM_152426 NP_689639
Function	DNA deaminase (cytidine deaminase) which acts as an inhibitor of retrovirus replication and retrotransposon mobility via deaminase-dependent and -independent mechanisms. Exhibits antiviral activity against vif-deficient HIV-1. After the penetration of retroviral nucleocapsids into target cells of infection and the initiation of reverse transcription, it can induce the conversion of cytosine to uracil in the minus-sense single-strand viral DNA, leading to G-to-A hypermutations in the subsequent plus-strand viral DNA. The resultant detrimental levels of mutations in the proviral genome, along with a deamination- independent mechanism that works prior to the proviral integration, together exert efficient antiretroviral effects in infected target cells. Selectively targets single-stranded DNA and does not deaminate double-stranded DNA or single-or double- stranded RNA. May inhibit the mobility of LTR and non-LTR retrotransposons. {ECO:0000269|PubMed:12859895, ECO:0000269|PubMed:20062055, E
Subcellular Location	Cytoplasm. Cytoplasm, P-body.
Tissue Specificity	Expressed in lymphoid organs. Also detected in non-lymphoid tissues including lung. {ECO:0000269|PubMed:20308164}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human APOBEC3D full length protein - ab165460 from Abcam Category Protein Prices $402.00 Sizes 10 µg Source Wheat germ Species Human

APOBEC3D Antibody Blocking Peptide - LS-E6141 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human APOBEC3D Protein - H00140564-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

APOBEC3D-Antibody-N-term-Blocking-Peptide - BP18763a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

ApoBEC3D Blocking Peptide - 33R-8959 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

APOBEC3D Peptide - AC21-2495-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

APOBEC3D - H00140564-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

APOBEC3D - H00140564-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

APOBEC3D Peptide - 42-853P from ProSci Category Peptide Species Human

APOBEC3D fusion protein - ag20233 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

APOBEC3D fusion protein - ag20194 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Human APOBEC3D, His-tagged - APOBEC3D-9756H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human Probable DNA dC->dU-editing enzyme APOBEC-3D(APOBEC3D) - CSB-YP846585HU CSB-EP846585HU CSB-BP846585HU CSB-MP846585HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

Probable DNA dC->dU-editing enzyme APOBEC-3D (APOBEC3D), Recombinant Protein - MBS1349231 from MyBioSource Category Protein Prices $1,155.00, $1,155.00, $1,385.00, $1,385.00, $1,845.00, $1,845.00, $2,310.00, $2,310.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

APOBEC3D, Peptide - MBS428131 from MyBioSource Category Peptide Prices $175.00 Sizes 100 µg Species Human

APOBEC3D, Peptide - MBS427727 from MyBioSource Category Peptide Prices $175.00 Sizes 100 µg Species Human

APOBEC3D Recombinant Protein Antigen - NBP2-49168PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E. coli Species Human

APOBEC3D Peptide, Human - M34GP00777H from Creative Peptides Category Peptide Source Synthetic. Species Human

APOBEC3D Immunizing peptide - orb17774 from Biorbyt Category Peptide

APOBEC3D Immunizing peptide - orb66184 from Biorbyt Category Peptide

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