APOBEC3D

Gene Symbol APOBEC3D
Entrez Gene 140564
Alt Symbol A3D, APOBEC3DE, APOBEC3E, ARP6
Species Human
Gene Type protein-coding
Description apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3D
Other Description DNA dC->dU-editing enzyme APOBEC-3D|apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3E pseudogene|probable DNA dC->dU-editing enzyme APOBEC-3D
Swissprots Q96AK3 Q5JZ91 Q7Z2N6
Accessions EAW60285 EAW60286 Q96AK3 BC017022 BC148619 AAI48620 BC153185 AAI53186 BE888971 BF832090 BM917407 BX340829 CR456396 CAG30282 CU012954 CAK54385 CU013242 CAK54684 DA287097 DB121958 EU527884 ACB32248 XM_005261337 XP_005261394 XM_006724139 XP_006724202 XM_011529892 XP_011528194 NM_152426 NP_689639
Function DNA deaminase (cytidine deaminase) which acts as an inhibitor of retrovirus replication and retrotransposon mobility via deaminase-dependent and -independent mechanisms. Exhibits antiviral activity against vif-deficient HIV-1. After the penetration of retroviral nucleocapsids into target cells of infection and the initiation of reverse transcription, it can induce the conversion of cytosine to uracil in the minus-sense single-strand viral DNA, leading to G-to-A hypermutations in the subsequent plus-strand viral DNA. The resultant detrimental levels of mutations in the proviral genome, along with a deamination- independent mechanism that works prior to the proviral integration, together exert efficient antiretroviral effects in infected target cells. Selectively targets single-stranded DNA and does not deaminate double-stranded DNA or single-or double- stranded RNA. May inhibit the mobility of LTR and non-LTR retrotransposons. {ECO:0000269|PubMed:12859895, ECO:0000269|PubMed:20062055, E
Subcellular Location Cytoplasm. Cytoplasm, P-body.
Tissue Specificity Expressed in lymphoid organs. Also detected in non-lymphoid tissues including lung. {ECO:0000269|PubMed:20308164}.

APOBEC3D CRISPR/Cas9 KO Plasmid (h) - sc-409507 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

APOBEC3D HDR Plasmid (h) - sc-409507-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

APOBEC3D Double Nickase Plasmid (h) - sc-409507-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

APOBEC3D Double Nickase Plasmid (h2) - sc-409507-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

APOBEC3D CRISPR Activation Plasmid (h) - sc-409507-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

APOBEC3D CRISPR Activation Plasmid (h2) - sc-409507-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

APOBEC3D Lentiviral Activation Particles (h) - sc-409507-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

APOBEC3D Lentiviral Activation Particles (h2) - sc-409507-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

APOBEC3D siRNA (h) - sc-72516 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

APOBEC3D shRNA Plasmid (h) - sc-72516-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

APOBEC3D shRNA (h) Lentiviral Particles - sc-72516-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

APOBEC3D RNAi - H00140564-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU042291 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN3337 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND3337 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

shRNA set against Human APOBEC3D (NM_152426.3) - SHH238442 from Creative biogene

Category siRNA
Species Reactivities Human

APOBEC3D miRNA 3'UTR clone - MiUTR3H-10880 from Creative biogene

Species Reactivities Human
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