P2RX7

Gene Symbol	P2RX7
Entrez Gene	5027
Alt Symbol	P2X7
Species	Human
Gene Type	protein-coding
Description	purinergic receptor P2X, ligand gated ion channel, 7
Other Description	ATP receptor|P2X purinoceptor 7|P2X7 receptor|P2Z receptor|purinergic receptor P2X, ligand-gated ion channel, 7|purinergic receptor P2X7 variant A
Swissprots	F5H6P2 E7EMK6 F8W951 Q4VKI1 Q4VKH9 O14991 A8K2Z0 Q4VKI3 Q96EV7 F5H7E8 Q4VKI0 Q99572 Q4VKH8 Q7Z771 Q4VKI4 Q4VKI2
Accessions	CAA73360 EAW98239 EAW98240 Q99572 AB209709 BAD92946 AK090866 BAG52241 AK225163 AK290405 BAF83094 AK294126 BAH11678 AK296432 BAH12350 AY847298 AAX82087 AY847299 AAX82088 AY847300 AAX82089 AY847301 AAX82090 AY847302 AAX82091 AY847303 AAX82092 AY847304 AAX82093 BC007679 AAH07679 BC011913 AAH11913 BC121157 AAI21158 BC121158 BI598073 DA274887 DA302256 DQ399293 ABD59798 DQ893457 ABM84383 DQ896337 ABM87336 GQ180122 ACS72266 JX471562 AFU91507 Y09561 CAA70755 XM_011538418 XP_011536720 XM_011538419 XP_011536721 XM_011538420 XP_011536722 NM_002562 NP_002553 NR_033948 NR_033949 NR_033950 NR_033951 NR_033952 NR_033953 NR_033954 NR_033955 NR_033956 NM_177427
Function	Receptor for ATP that acts as a ligand-gated ion channel. Responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Could function in both fast synaptic transmission and the ATP-mediated lysis of antigen-presenting cells.
Subcellular Location	Cell membrane {ECO:0000269|PubMed:12107182}; Multi-pass membrane protein.
Tissue Specificity	Widely expressed with highest levels in brain and immune tissues. {ECO:0000269|PubMed:15896293}.
Top Pathways	Calcium signaling pathway, Neuroactive ligand-receptor interaction

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human P2RX7 full length protein - ab159042 from Abcam Category Protein Source Wheat germ Species Human

P2RX7 peptide - ab191248 from Abcam Category Peptide

P2RX7 peptide - ab117069 from Abcam Category Peptide

P2RX7 / P2X7 Antibody Blocking Peptide - LS-E27121 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

P2RX7 / P2X7 Antibody Blocking Peptide - LS-E7925 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

P2RX7 / P2X7 Antibody Blocking Peptide - LS-E12494 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

P2RX7 / P2X7 Antibody Blocking Peptide - LS-E12637 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

P2RX7 / P2X7 Antibody Blocking Peptide - LS-E29698 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

Recombinant Human P2X7/P2RX7 Protein - H00005027-P01 from Novus Biologicals Category Protein Prices $305.00, $445.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

P2RX7-Antibody-C-term-Blocking-peptide - BP5674b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

P2X7 blocking peptide - GTX88360-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human, Mouse, Dog, Rat

P2RX7 Blocking Peptide - 33R-4125 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

P2RX7 Blocking Peptide - 33R-9617 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

P2RX7 Blocking Peptide - 33R-5361 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

P2RX7 Peptide - AC21-1942-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

P2RX7 / P2X7 - H00005027-P01 from Acris Antibodies Category Protein Prices $340.00 Sizes 2 µg Species Human

P2RX7 Peptide - 42-772P from ProSci Category Peptide Species Human

P2RX7 Peptide - 8015P from ProSci Category Peptide Species Human

P2RX7 fusion protein - Ag1600 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

P2RX7 fusion protein - ag16932 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

Recombinant Human P2RX7, GST-tagged - P2RX7-1494H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Purinergic Receptor P2X, Ligand Gated Ion Channel 7 (P2RX7) - RPG077Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

Recombinant Purinergic Receptor P2X, Ligand Gated Ion Channel 7 (P2RX7) - RPG077Hu01 from Cloud-clone Category Protein Source E.coli Species Human

P2RX7/P2X7 receptor, Peptide - MBS425014 from MyBioSource Category Peptide Prices $175.00 Sizes 100 µg Species Human, Mouse, Rat, Dog

P2X7/P2RX7 Recombinant Protein Antigen - NBP2-13720PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

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