P2RX7

Gene Symbol P2RX7
Entrez Gene 5027
Alt Symbol P2X7
Species Human
Gene Type protein-coding
Description purinergic receptor P2X, ligand gated ion channel, 7
Other Description ATP receptor|P2X purinoceptor 7|P2X7 receptor|P2Z receptor|purinergic receptor P2X, ligand-gated ion channel, 7|purinergic receptor P2X7 variant A
Swissprots F5H6P2 E7EMK6 F8W951 Q4VKI1 Q4VKH9 O14991 A8K2Z0 Q4VKI3 Q96EV7 F5H7E8 Q4VKI0 Q99572 Q4VKH8 Q7Z771 Q4VKI4 Q4VKI2
Accessions CAA73360 EAW98239 EAW98240 Q99572 AB209709 BAD92946 AK090866 BAG52241 AK225163 AK290405 BAF83094 AK294126 BAH11678 AK296432 BAH12350 AY847298 AAX82087 AY847299 AAX82088 AY847300 AAX82089 AY847301 AAX82090 AY847302 AAX82091 AY847303 AAX82092 AY847304 AAX82093 BC007679 AAH07679 BC011913 AAH11913 BC121157 AAI21158 BC121158 BI598073 DA274887 DA302256 DQ399293 ABD59798 DQ893457 ABM84383 DQ896337 ABM87336 GQ180122 ACS72266 JX471562 AFU91507 Y09561 CAA70755 XM_011538418 XP_011536720 XM_011538419 XP_011536721 XM_011538420 XP_011536722 NM_002562 NP_002553 NR_033948 NR_033949 NR_033950 NR_033951 NR_033952 NR_033953 NR_033954 NR_033955 NR_033956 NM_177427
Function Receptor for ATP that acts as a ligand-gated ion channel. Responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Could function in both fast synaptic transmission and the ATP-mediated lysis of antigen-presenting cells.
Subcellular Location Cell membrane {ECO:0000269|PubMed:12107182}; Multi-pass membrane protein.
Tissue Specificity Widely expressed with highest levels in brain and immune tissues. {ECO:0000269|PubMed:15896293}.
Top Pathways Calcium signaling pathway, Neuroactive ligand-receptor interaction

P2X7 CRISPR/Cas9 KO Plasmid (h) - sc-400780 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

P2X7 HDR Plasmid (h) - sc-400780-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

P2X7 Double Nickase Plasmid (h) - sc-400780-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

P2X7 Double Nickase Plasmid (h2) - sc-400780-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

P2X7 CRISPR Activation Plasmid (h) - sc-400780-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

P2X7 CRISPR Activation Plasmid (h2) - sc-400780-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

P2X7 Lentiviral Activation Particles (h) - sc-400780-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

P2X7 Lentiviral Activation Particles (h2) - sc-400780-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

P2X7 siRNA (h) - sc-42575 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

P2X7 shRNA Plasmid (h) - sc-42575-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

P2X7 shRNA (h) Lentiviral Particles - sc-42575-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

P2X7/P2RX7 RNAi - H00005027-R01 from Novus Biologicals

Category siRNA
Prices $409.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU146001 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN2093 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2093 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR08552 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr08552

P2RX7 siRNA (Human) - CRH3340 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

P2X7/P2RX7 RNAi - H00005027-R02 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

shRNA set against Human P2RX7 (NM_002562.5) - SHH369512 from Creative biogene

Category siRNA
Species Reactivities Human

Human P2RX7 siRNA - orb263842 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

P2RX7 shRNA Plasmid (Human) - CHH3340 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

P2RX7 miRNA 3'UTR clone - MiUTR3H-05082 from Creative biogene

Species Reactivities Human
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