SLC16A1

Gene Symbol	SLC16A1
Entrez Gene	6566
Alt Symbol	HHF7, MCT, MCT1, MCT1D
Species	Human
Gene Type	protein-coding
Description	solute carrier family 16 (monocarboxylate transporter), member 1
Other Description	MCT 1|monocarboxylate transporter 1|solute carrier family 16 (monocarboxylic acid transporters), member 1|solute carrier family 16, member 1 (monocarboxylic acid transporter 1)
Swissprots	Q49A45 Q5T8R6 P53985 Q9NSJ9
Accessions	CAD27707 EAW56551 EAW56552 EAW56553 P53985 AF239919 AI656300 AJ438942 AJ438943 AK000641 AK094064 AK296688 BAG59282 AK303603 BAG64618 AK312500 BAG35402 AL162079 CAB82412 BC026317 AAH26317 BC045664 AAH45664 BM712667 BP294493 DB443025 DQ895286 ABM86212 EU176206 ABW03657 EU831949 ACE87390 EU832043 ACE86705 L31801 AAC41707 XM_011542026 XP_011540328 XM_011542027 XP_011540329 XM_011548725 XP_011547027 XM_011548726 XP_011547028 NM_001166496 NP_001159968 NM_003051 NP_003042
Function	Proton-coupled monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate. Depending on the tissue and on cicumstances, mediates the import or export of lactic acid and ketone bodies. Required for normal nutrient assimilation, increase of white adipose tissue and body weight gain when on a high-fat diet. Plays a role in cellular responses to a high-fat diet by modulating the cellular levels of lactate and pyruvate, small molecules that contribute to the regulation of central metabolic pathways and insulin secretion, with concomitant effects on plasma insulin levels and blood glucose homeostasis. {ECO:0000269|PubMed:17701893}.
Subcellular Location	Cell membrane {ECO:0000269|PubMed:15505343, ECO:0000269|PubMed:17127621, ECO:0000269|PubMed:24390345}; Multi- pass membrane protein {ECO:0000269|PubMed:15505343, ECO:0000269|PubMed:17127621, ECO:0000269|PubMed:24390345}.
Tissue Specificity	Detected in heart and in blood lymphocytes and monocytes (at protein level). Widely expressed. {ECO:0000269|PubMed:15505343}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human Monocarboxylic acid transporter 1 full length protein - ab152689 from Abcam Category Protein Source Wheat germ Species Human

Human Monocarboxylic acid transporter 1 peptide - ab97985 from Abcam Category Peptide

Human Monocarboxylic acid transporter 1 peptide - ab22782 from Abcam Category Peptide Species Human

SLC16A1 / MCT1 Antibody Blocking Peptide - LS-E7072 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

SLC16A1 / MCT1 Antibody Blocking Peptide - LS-E7073 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

SLC16A1 / MCT1 Antibody Blocking Peptide - LS-E16119 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human MCT1/SLC16A1 Protein - H00006566-P01 from Novus Biologicals Category Protein Prices $319.00 Sizes 2 µg Source Wheat Germ Species Human

MCT1/SLC16A1 Peptide - P1244 from Novus Biologicals Category Peptide Species Human

MCT1/SLC16A1 Peptide - P1243 from Novus Biologicals Category Peptide Species Human

MCT1-SLC16A1-Antibody-Center-Blocking-peptide - BP2753c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

MCT1-SLC16A1-Antibody-C-term-Blocking-peptide - BP2753b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

SLC16A1 Blocking Peptide - 33R-2496 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

SLC16A1 Blocking Peptide - 33R-4596 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

SLC16A1 - H00006566-P01 from Acris Antibodies Category Protein Prices $310.00 Sizes 2 µg Species Human

MCT1 fusion protein - Ag14098 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

MCT1 fusion protein - Ag14512 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

Recombinant Human MCT1, GST-tagged - MCT1-788H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Solute Carrier Family 16, Member 1 (SLC16A1) - RPE431Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

Recombinant Solute Carrier Family 16, Member 1 (SLC16A1) - RPE431Ra01 from Uscn Life Science Inc. Category Protein Source E.coli Species Rat

SLC16A1 - TP305213 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

MCT1/SLC16A1 Recombinant Protein Antigen - NBP1-89574PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

SLC16A1 Peptide, Human - M34GP14335H from Creative Peptides Category Peptide Source Synthetic. Species Human

Monocarboxylate transporter 1 (SLC16A1), Recombinant Protein - MBS1047614 from MyBioSource Category Protein Source E Coli or Yeast or Baculovirus or Mammalian Cell

Monocarboxylate transporter 1 (SLC16A1), Recombinant Protein - MBS7029839 from MyBioSource Category Protein Prices $925.00, $1,905.00, $3,115.00 Sizes 10 µg, 50 µg, 100 µg Source Cell Free Expression

Monocarboxylate transporter 1 (SLC16A1), Recombinant Protein - MBS957068 from MyBioSource Category Protein Prices $1,375.00, $1,835.00 Sizes 1 mg (E-Coli), 1 mg (Yeast) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

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