SLC16A1

Gene Symbol	SLC16A1
Entrez Gene	6566
Alt Symbol	HHF7, MCT, MCT1, MCT1D
Species	Human
Gene Type	protein-coding
Description	solute carrier family 16 (monocarboxylate transporter), member 1
Other Description	MCT 1|monocarboxylate transporter 1|solute carrier family 16 (monocarboxylic acid transporters), member 1|solute carrier family 16, member 1 (monocarboxylic acid transporter 1)
Swissprots	Q49A45 Q5T8R6 P53985 Q9NSJ9
Accessions	CAD27707 EAW56551 EAW56552 EAW56553 P53985 AF239919 AI656300 AJ438942 AJ438943 AK000641 AK094064 AK296688 BAG59282 AK303603 BAG64618 AK312500 BAG35402 AL162079 CAB82412 BC026317 AAH26317 BC045664 AAH45664 BM712667 BP294493 DB443025 DQ895286 ABM86212 EU176206 ABW03657 EU831949 ACE87390 EU832043 ACE86705 L31801 AAC41707 XM_011542026 XP_011540328 XM_011542027 XP_011540329 XM_011548725 XP_011547027 XM_011548726 XP_011547028 NM_001166496 NP_001159968 NM_003051 NP_003042
Function	Proton-coupled monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate. Depending on the tissue and on cicumstances, mediates the import or export of lactic acid and ketone bodies. Required for normal nutrient assimilation, increase of white adipose tissue and body weight gain when on a high-fat diet. Plays a role in cellular responses to a high-fat diet by modulating the cellular levels of lactate and pyruvate, small molecules that contribute to the regulation of central metabolic pathways and insulin secretion, with concomitant effects on plasma insulin levels and blood glucose homeostasis. {ECO:0000269|PubMed:17701893}.
Subcellular Location	Cell membrane {ECO:0000269|PubMed:15505343, ECO:0000269|PubMed:17127621, ECO:0000269|PubMed:24390345}; Multi- pass membrane protein {ECO:0000269|PubMed:15505343, ECO:0000269|PubMed:17127621, ECO:0000269|PubMed:24390345}.
Tissue Specificity	Detected in heart and in blood lymphocytes and monocytes (at protein level). Widely expressed. {ECO:0000269|PubMed:15505343}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

MCT1 (H-1) - sc-365501 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Mouse Clonality Monoclonal

MCT1 (C-20) - sc-14916 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

MCT1 (H-70) - sc-50324 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Rabbit Clonality Polyclonal

MCT1 (T-19) - sc-14917 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

Anti-Monocarboxylic acid transporter 1 antibody - ab90582 from Abcam Prices $385.00 Sizes 50 µg Host Mouse Clonality Polyclonal

Anti-Monocarboxylic acid transporter 1 antibody - ab85021 from Abcam Prices $392.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-Monocarboxylic acid transporter 1 antibody - ab98868 from Abcam Prices $376.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-Monocarboxylic acid transporter 1 antibody - ab135520 from Abcam Prices $376.00 Sizes 400 µl Host Rabbit Clonality Polyclonal

Anti-Monocarboxylic acid transporter 1 antibody [ERR13706(B)] - C-terminal - ab179832 from Abcam Prices $99.00 Sizes 10 µl Host Rabbit Clonality Monoclonal Clone ERR13706(B)

Anti-SLC16A1 / MCT1 Antibody (C-Terminus) - LS-C16583 from LifeSpan Bioscience Prices $590.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-SLC16A1 / MCT1 Antibody (C-Terminus) - LS-C16584 from LifeSpan Bioscience Prices $415.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

Anti-SLC16A1 / MCT1 Antibody (C-Terminus) - LS-C16585 from LifeSpan Bioscience Prices $365.00 Sizes 50 µl Host Rabbit Clonality Polyclonal

Anti-SLC16A1 / MCT1 Antibody (aa430-460) - LS-C98631 from LifeSpan Bioscience Prices $295.00 Sizes 400 µl Host Rabbit Clonality Polyclonal

Anti-SLC16A1 / MCT1 Antibody (aa200-228) - LS-C98632 from LifeSpan Bioscience Prices $295.00 Sizes 400 µl Host Rabbit Clonality Polyclonal

Anti-SLC16A1 / MCT1 Antibody - LS-C341521 from LifeSpan Bioscience Prices $385.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-SLC16A1 / MCT1 Antibody (aa201-250) - LS-C80613 from LifeSpan Bioscience Prices $325.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-SLC16A1 / MCT1 Antibody (aa450-500) - LS-C290993 from LifeSpan Bioscience Prices $375.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-SLC16A1 / MCT1 Antibody (aa215-264) - LS-C107945 from LifeSpan Bioscience Prices $365.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

Anti-SLC16A1 / MCT1 Antibody (aa200-250) - LS-C290994 from LifeSpan Bioscience Prices $375.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-SLC16A1 / MCT1 Antibody - LS-C335287 from LifeSpan Bioscience Prices $255.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

Anti-SLC16A1 / MCT1 Antibody (aa236-254) - LS-C313513 from LifeSpan Bioscience Prices $305.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

MCT1/SLC16A1 Antibody - NBP1-59656 from Novus Biologicals Prices $99.00, $299.00 Sizes 25 µg, 100 µg Host Rabbit Clonality Polyclonal

MCTS1 Antibody (882616) [Unconjugated] - MAB8275 from Novus Biologicals Prices $99.00, $249.00 Sizes 25 µg, 100 µg Host Mouse Clonality Monoclonal Clone 882616

MCT1/SLC16A1 Antibody - H00006566-B01P from Novus Biologicals Prices $359.00 Sizes 50 µg Host Mouse Clonality Polyclonal

MCT1/SLC16A1 Antibody - NBP1-59879 from Novus Biologicals Prices $139.00, $329.00 Sizes 20 µl, 100 µl Host Rabbit Clonality Polyclonal

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