CREB3L3

Gene Symbol CREB3L3
Entrez Gene 84699
Alt Symbol CREB-H, CREBH, HYST1481
Species Human
Gene Type protein-coding
Description cAMP responsive element binding protein 3-like 3
Other Description CREB/ATF family transcription factor|cyclic AMP-responsive element-binding protein 3-like protein 3
Swissprots Q6ZMC5 B7ZL69 Q68CJ9 M0QYW7 B2R7S6 Q96TB9
Accessions AAC34469 EAW69260 EAW69261 Q68CJ9 AB050902 BAB47242 AB073612 BAD38649 AK172839 BAD18804 AK313099 BAG35923 BC101504 AAI01505 BC101508 AAI01509 BC143609 AAI43610 BC143610 DA210258 EU446882 ABZ92411 NM_001271995 NP_001258924 NM_001271996 NP_001258925 NM_001271997 NP_001258926 NM_032607 NP_115996
Function Transcription factor that may act during endoplasmic reticulum stress by activating unfolded protein response target genes. Activated in response to cAMP stimulation. In vitro, binds to the cAMP response element (CRE) and box-B element. Activates transcription through box-B element. Activates transcription through CRE (By similarity). Seems to function synergistically with ATF6. In acute inflammatory response, may activate expression of acute phase response (APR) genes. May be involved in growth suppression. {ECO:0000250, ECO:0000269|PubMed:11353085, ECO:0000269|PubMed:15800215, ECO:0000269|PubMed:16469704}.
Subcellular Location Endoplasmic reticulum membrane {ECO:0000269|PubMed:11353085}; Single-pass type II membrane protein {ECO:0000269|PubMed:11353085}.
Tissue Specificity Exclusively expressed in liver. Underexpressed in hepatocellular carcinoma tissues. {ECO:0000269|PubMed:11353085, ECO:0000269|PubMed:15800215}.
Top Pathways cGMP-PKG signaling pathway, Huntington's disease, Glucagon signaling pathway, Prostate cancer, PI3K-Akt signaling pathway

CREB-H (D10D8) Rabbit mAb - 8700 from Cell Signaling Technology

Host Rabbit
Clonality Monoclonal
Clone D10D8

CREB3L3 (G-11) - sc-377156 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
CREB3L3 (G-11): sc-377156. Western blot analysis of CREB3L3 expression in non-transfected: sc-117752 (A) and human CREB3L3 transfected: sc-370151 (B) 293T whole cell lysates.

CREB3L3 (G-20) - sc-69374 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
CREB3L3 (G-20): sc-69374. Western blot analysis of CREB3L3 expression in human liver tissue extract.

CREB3L3 (M-223) - sc-292134 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

CREB3L3 (H-148) - sc-292135 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
CREB3L3 (H-148): sc-292135. Western blot analysis of CREB3L3 expression in non-transfected: sc-117752 (A) and human CREB3L3 transfected: sc-370151 (B) 293T whole cell lysates and mouse liver tissue extract (C).

CREB3L3 (N-14) - sc-69375 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
CREB3L3 (N-14): sc-69375. Immunoperoxidase staining of formalin fixed, paraffin-embedded human duodenum tissue showing nuclear and cytoplasmic staining of glandular cells.

CREB3L3 (E-5) - sc-377363 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
CREB3L3 (E-5): sc-377363. Western blot analysis of CREB3L3 expression in non-transfected: sc-117752 (A) and human CREB3L3 transfected: sc-370151 (B) whole cell lysates.

Anti-CREB3L3 antibody - ab111938 from Abcam

Prices $370.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Anti-CREB3L3 antibody (ab111938) at 1/1000 dilution + IMR32 whole cell lysate at 30 µg

Anti-CREB3L3 antibody - ab150865 from Abcam

Prices $443.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of Paraffin-embedded Human liver tissue labeling CREB3L3 with ab150865 at 1/200 dilution.

Anti-CREBH / CREB3L3 Antibody (aa30-44) - LS-C3157 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

CREB3L3 Antibody - NBP2-16008 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

CREB3L3 Antibody - NBP2-38785 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: CREB3L3 Antibody [NBP2-38785] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10. Lane 2: Human cell line RT-4. Lane 3: Human cell line U-251MG. Lane 4: Human Plasma. Lane 5: Human liver tissue. Lane 6: Human tonsil tissue

CREB3L3 Antibody - NBP2-13873 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry-Paraffin: CREB3L3 Antibody [NBP2-13873] - Staining of human small intestine shows moderate cytoplasmic positivity in glandular cells.

CREB-H/CREB3L3 Polyclonal Antibody - bs-11239R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

CREB-H/CREB3L3 Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-11239R-A350 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

CREB-H/CREB3L3 Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated - bs-11239R-A488 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

CREB-H/CREB3L3 Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated - bs-11239R-A555 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

CREB-H/CREB3L3 Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated - bs-11239R-A647 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

CREB-H/CREB3L3 Polyclonal Antibody, Cy3 Conjugated - bs-11239R-Cy3 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

CREB-H/CREB3L3 Polyclonal Antibody, Cy5 Conjugated - bs-11239R-Cy5 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

CREB-H/CREB3L3 Polyclonal Antibody, Cy5.5 Conjugated - bs-11239R-Cy5.5 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

CREB-H/CREB3L3 Polyclonal Antibody, Cy7 Conjugated - bs-11239R-Cy7 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

CREB-H/CREB3L3 Polyclonal Antibody, FITC Conjugated - bs-11239R-FITC from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

CREB-H/CREB3L3 Polyclonal Antibody, Biotin Conjugated - bs-11239R-Biotin from Bioss

Prices $349.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

CREB-H/CREB3L3 Polyclonal Antibody, HRP Conjugated - bs-11239R-HRP from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Search more