CREB3L3

Gene Symbol CREB3L3
Entrez Gene 84699
Alt Symbol CREB-H, CREBH, HYST1481
Species Human
Gene Type protein-coding
Description cAMP responsive element binding protein 3-like 3
Other Description CREB/ATF family transcription factor|cyclic AMP-responsive element-binding protein 3-like protein 3
Swissprots Q6ZMC5 B7ZL69 Q68CJ9 M0QYW7 B2R7S6 Q96TB9
Accessions AAC34469 EAW69260 EAW69261 Q68CJ9 AB050902 BAB47242 AB073612 BAD38649 AK172839 BAD18804 AK313099 BAG35923 BC101504 AAI01505 BC101508 AAI01509 BC143609 AAI43610 BC143610 DA210258 EU446882 ABZ92411 NM_001271995 NP_001258924 NM_001271996 NP_001258925 NM_001271997 NP_001258926 NM_032607 NP_115996
Function Transcription factor that may act during endoplasmic reticulum stress by activating unfolded protein response target genes. Activated in response to cAMP stimulation. In vitro, binds to the cAMP response element (CRE) and box-B element. Activates transcription through box-B element. Activates transcription through CRE (By similarity). Seems to function synergistically with ATF6. In acute inflammatory response, may activate expression of acute phase response (APR) genes. May be involved in growth suppression. {ECO:0000250, ECO:0000269|PubMed:11353085, ECO:0000269|PubMed:15800215, ECO:0000269|PubMed:16469704}.
Subcellular Location Endoplasmic reticulum membrane {ECO:0000269|PubMed:11353085}; Single-pass type II membrane protein {ECO:0000269|PubMed:11353085}.
Tissue Specificity Exclusively expressed in liver. Underexpressed in hepatocellular carcinoma tissues. {ECO:0000269|PubMed:11353085, ECO:0000269|PubMed:15800215}.
Top Pathways cGMP-PKG signaling pathway, Huntington's disease, Glucagon signaling pathway, Prostate cancer, PI3K-Akt signaling pathway

CREB3L3 CRISPR/Cas9 KO Plasmid (h) - sc-402596 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CREB3L3 HDR Plasmid (h) - sc-402596-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CREB3L3 Double Nickase Plasmid (h) - sc-402596-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CREB3L3 Double Nickase Plasmid (h2) - sc-402596-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CREB3L3 CRISPR Activation Plasmid (h) - sc-402596-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CREB3L3 CRISPR Activation Plasmid (h2) - sc-402596-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CREB3L3 Lentiviral Activation Particles (h) - sc-402596-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CREB3L3 Lentiviral Activation Particles (h2) - sc-402596-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CREB3L3 siRNA (h) - sc-72999 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CREB3L3 shRNA Plasmid (h) - sc-72999-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CREB3L3 shRNA (h) Lentiviral Particles - sc-72999-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CREB3L3 RNAi - H00084699-R01 from Novus Biologicals

Category siRNA
Prices $409.00
Sizes 20 nmol
Species Reactivities Human

CompoZr® Knockout ZFN Kit - CKOZFN6555 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND6555 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

CREB3L3 siRNA (Human) - CRJ3591 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

CREB3L3 - MBS8206101 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human Creb3l3 (NM_032607.1) - SHH269334 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human CREB3L3(NM_032607.1) - SHG198217 from Creative biogene

Category siRNA
Species Reactivities Human

CREB3L3 shRNA Plasmid (Human) - CHJ3591 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

CREB3L3 miRNA 3'UTR clone - MiUTR1H-02412 from Creative biogene

Species Reactivities Human
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