CREB3L3

Gene Symbol CREB3L3
Entrez Gene 84699
Alt Symbol CREB-H, CREBH, HYST1481
Species Human
Gene Type protein-coding
Description cAMP responsive element binding protein 3-like 3
Other Description CREB/ATF family transcription factor|cyclic AMP-responsive element-binding protein 3-like protein 3
Swissprots Q6ZMC5 B7ZL69 Q68CJ9 M0QYW7 B2R7S6 Q96TB9
Accessions AAC34469 EAW69260 EAW69261 Q68CJ9 AB050902 BAB47242 AB073612 BAD38649 AK172839 BAD18804 AK313099 BAG35923 BC101504 AAI01505 BC101508 AAI01509 BC143609 AAI43610 BC143610 DA210258 EU446882 ABZ92411 NM_001271995 NP_001258924 NM_001271996 NP_001258925 NM_001271997 NP_001258926 NM_032607 NP_115996
Function Transcription factor that may act during endoplasmic reticulum stress by activating unfolded protein response target genes. Activated in response to cAMP stimulation. In vitro, binds to the cAMP response element (CRE) and box-B element. Activates transcription through box-B element. Activates transcription through CRE (By similarity). Seems to function synergistically with ATF6. In acute inflammatory response, may activate expression of acute phase response (APR) genes. May be involved in growth suppression. {ECO:0000250, ECO:0000269|PubMed:11353085, ECO:0000269|PubMed:15800215, ECO:0000269|PubMed:16469704}.
Subcellular Location Endoplasmic reticulum membrane {ECO:0000269|PubMed:11353085}; Single-pass type II membrane protein {ECO:0000269|PubMed:11353085}.
Tissue Specificity Exclusively expressed in liver. Underexpressed in hepatocellular carcinoma tissues. {ECO:0000269|PubMed:11353085, ECO:0000269|PubMed:15800215}.
Top Pathways cGMP-PKG signaling pathway, Huntington's disease, Glucagon signaling pathway, Prostate cancer, PI3K-Akt signaling pathway

CREB3L3 fusion protein - ag16715 from Proteintech Group

Category Protein
Source E. coli-derived, PET28a
Species Human

CREB3L3 fusion protein - ag16328 from Proteintech Group

Category Protein
Source E. coli-derived, PGEX-4T
Species Human

Recombinant Human Cyclic AMP-responsive element-binding protein 3-like protein 3 - CSB-YP715009HU CSB-EP715009HU CSB-BP715009HU CSB-MP715009HU from Cusabio

Category Protein
Source Yeast or E.coli or Baculovirus or Mammalian cell
Species Human

CREB3L3 Recombinant Protein Antigen - NBP2-13873PEP from Novus Biologicals

Category Protein
Prices $199.00
Sizes 100 µl
Source E.coli
Species Human

CREB3L3 Recombinant Protein Antigen - NBP2-38785PEP from Novus Biologicals

Category Protein
Prices $199.00
Sizes 100 µl
Source E.coli
Species Human

CREB3L3-Blocking-Peptide-Center - BP21763c from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

CREB3L3 Peptide, Human - M34GP03623H from Creative Peptides

Category Peptide
Source Synthetic.
Species Human

CREB3L3 peptide - orb13052 from Biorbyt

Category Peptide
Prices $170.00
Sizes 1 mg

Cyclic AMP-responsive element-binding protein 3-like protein 3 (CREB3L3), Recombinant Protein - MBS1364736 from MyBioSource

Category Protein
Prices $1,080.00, $1,080.00, $1,315.00, $1,315.00, $1,700.00, $1,700.00, $2,165.00, $2,165.00
Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell)
Source E Coli or Yeast or Baculovirus or Mammalian Cell
Species Human
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