DBNL

Gene Symbol DBNL
Entrez Gene 28988
Alt Symbol ABP1, HIP-55, HIP55, SH3P7
Species Human
Gene Type protein-coding
Description drebrin-like
Other Description HPK1-interacting protein of 55 kDa|SH3 domain-containing protein 7|cervical SH3P7|cervical mucin-associated protein|drebrin-F|drebrin-like protein|src homology 3 domain-containing protein HIP-55
Swissprots Q96K74 Q6IAI8 P84070 C9J7P1 Q9NR72 B4DDP6 Q9HBN8 Q96F30 Q9UJU6 A4D2I9 B4DEM2
Accessions EAL23770 EAW61129 EAW61130 EAW61131 EAW61132 Q9UJU6 AB209486 BAD92723 AF077353 AAF80228 AF151364 AAG13120 AF197060 AAF13701 AF218020 AAG17262 AF250287 AAF81273 AK027367 BAB55065 AK126142 AK293151 BAG56697 AK293279 BAG56807 AK293340 BAG56856 AK293698 BAG57133 AK296778 BAG59356 AK298102 BAG60387 AK300630 BAG62321 AK302037 BAG63431 BC011677 AAH11677 BC023589 BC031687 AAH31687 CR457167 CAG33448 DC404852 HQ447892 ADQ32376 JF432143 ADZ15360 XM_011515325 XP_011513627 NM_001014436 NP_001014436 NM_001122956 NP_001116428 NM_001284313 NP_001271242 NM_001284315 NP_001271244 NM_014063 NP_054782
Function Adapter protein that binds F-actin and DNM1, and thereby plays a role in receptor-mediated endocytosis. Plays a role in the reorganization of the actin cytoskeleton, formation of cell projections, such as neurites, in neuron morphogenesis and synapse formation via its interaction with WASL and COBL. Does not bind G- actin and promote actin polymerization by itself. Required for the formation of organized podosome rosettes (By similarity). May act as a common effector of antigen receptor-signaling pathways in leukocytes. Acts as a key component of the immunological synapse that regulates T-cell activation by bridging TCRs and the actin cytoskeleton to gene activation and endocytic processes. {ECO:0000250, ECO:0000269|PubMed:14729663}.
Subcellular Location Cytoplasm, cytoskeleton. Cell projection, lamellipodium. Cell projection, ruffle {ECO:0000250}. Cytoplasm, cell cortex {ECO:0000250}. Cytoplasm, cytosol {ECO:0000250}. Cell junction, synapse {ECO:0000250}. Cell projection {ECO:0000250}. Cell membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Cytoplasmic vesicle, clathrin-coated vesicle membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Golgi apparatus membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Cell projection, podosome {ECO:0000250}. Note=Detected in neuron cell body and cell projections, such as neurites. Colocalizes with cytosolic dynamin in hippocampus neurons (By similarity). Cortical actin cytoskeleton. Associates with lamellipodial actin and membrane ruffles. Colocalizes with actin and cortactin at podosome dots and podosome rosettes (By similarity). {ECO:0000250}.

Amiloride-sensitive amine oxidase [copper-containing] (ABP1), Human, ELISA Kit - E01A1162 from ARP American Research Products

Category ELISA Kit
Prices $535.00, $735.00
Sizes 48 t, 96 t

Amiloride-sensitive amine oxidase [copper-containing], ABP1, Human, ELISA Kit - E0656h from ARP American Research Products

Category ELISA Kit
Prices $596.00
Sizes 96 t
Range 1.56-100 ng/mL

drebrin-like, ELISA Kit - MBS9337628 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

ELISA Kit for Drebrin Like Protein (DBNL) - SEL448Hu from Cloud-clone

Category ELISA Kit
Sensitivity The minimum detectable dose of this kit is typically less than 0.63ng/mL.
Range 1.563-100ng/mL The standard curve concentrations used for the ELISA's were 100ng/mL, 50ng/mL, 25ng/mL, 12.5ng/mL, 6.25ng/mL, 3.125ng/mL, 1.563ng/mL

ELISA Kit for Drebrin Like Protein (DBNL) - SEL448Hu from Uscn Life Science Inc.

Category ELISA Kit
Sensitivity The minimum detectable dose of this kit is typically less than 0.63ng/mL.
Range 1.56-100ng/mL The standard curve concentrations used for the ELISA’s were 100ng/mL, 50ng/mL, 25ng/mL, 12.5ng/mL, 6.25ng/mL, 3.13ng/mL, 1.56ng/mL

Human SH3P7 / HIP-55 ELISA Kit (Sandwich ELISA) - LS-F25588 from LifeSpan Bioscience

Category ELISA Kit
Prices $850.00
Sizes 1 plate
Sensitivity 0.63 ng/ml
Range 1.56-100 ng/ml

Human ABP1 ELISA Kit - abx570170 from Abbexa

Category ELISA Kit
Sensitivity 0.072 ng/ml
Range 0.156 ng/ml - 10 ng/ml

ABP1 - EKH1988 from Nordic BioSite

Sensitivity 0.938ng/ml
Range 1.56-100ng/ml

ABP1 ELISA Kit (Human) : 96 Wells (OKEH02625) - OKEH02625 from Aviva Systems Biology

Category ELISA Kit
Prices $420.00
Sizes 96 wells
Sensitivity < 0.56 ng/mL
Range 1.56 - 100 ng/mL

Human ABP1 ELISA Kit - E001776 from Biobool

Category ELISA Kit
Sensitivity 0.039 ng/ml

Human DBNL ELISA Kit - E012398 from Biobool

Category ELISA Kit
Sensitivity The minimum detectable dose of DBNL is typically less than 0.63ng/mL. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined by adding two

anti-ABP1 antibody - ARG55116 from Arigo Biolaboratories

Category ELISA Kit

anti-HIP-55 / SH3P7 antibody - ARG63442 from Arigo Biolaboratories

Category ELISA Kit

anti-DBNL / HIP-55 antibody - ARG55436 from Arigo Biolaboratories

Category ELISA Kit

Drebrin-like protein, ELISA Kit - MBS285979 from MyBioSource

Category ELISA Kit
Prices $465.00, $790.00, $3,500.00, $6,655.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
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