Gene Symbol | Fas |
---|---|
Entrez Gene | 14102 |
Alt Symbol | AI196731, APO1, APT1, CD95, TNFR6, Tnfrsf6, lpr |
Species | Mouse |
Gene Type | protein-coding |
Description | Fas (TNF receptor superfamily member 6) |
Other Description | FASLG receptor|Fas (TNF receptor superfamily member)|Fas antigen|apo-1 antigen|apoptosis-mediating surface antigen FAS|lymphoproliferation|tumor necrosis factor receptor superfamily member 6 |
Swissprots | Q9DCQ1 Q6GT31 P25446 |
Accessions | AAB25700 AAG02410 AAK27371 AAY51770 AAY51771 AAY51772 AAY51773 AAY51774 CAC00638 EDL41748 P25446 AK002590 BAB22211 AK086933 BAC39766 BC061160 AAH61160 BY348234 DQ846748 ABI24112 DQ846749 ABI24113 L15352 L15353 L25336 M83649 AAA37593 XM_011247141 XP_011245443 NM_001146708 NP_001140180 NM_007987 NP_032013 |
Function | Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death- inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS- mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both (By similarity). {ECO:0000250}. |
Subcellular Location | Membrane; Single-pass type I membrane protein. |
Tissue Specificity | Detected in various tissues including thymus, liver, lung, heart, and adult ovary. |
Top Pathways | Apoptosis, Proteoglycans in cancer, Non-alcoholic fatty liver disease (NAFLD), p53 signaling pathway, TNF signaling pathway |
FAS (A-20) - sc-1023 from Santa Cruz Biotechnology
|
||||||||||
FAS (M-20) - sc-716 from Santa Cruz Biotechnology
|
||||||||||
FAS (X-20) - sc-1024 from Santa Cruz Biotechnology
|
||||||||||
Anti-Fas antibody [0.T.44] - ab36919 from Abcam
|
||||||||||
Anti-Fas antibody [MFL3] (Biotin) - ab95640 from Abcam
|
||||||||||
Fas/TNFRSF6/CD95 Antibody - NB120-13550 from Novus Biologicals
|
||||||||||
CD95 Polyclonal Antibody - bs-0215R from Bioss
|
||||||||||
CD95 Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-0215R-A350 from Bioss
|
||||||||||
CD95 Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated - bs-0215R-A488 from Bioss
|
||||||||||
CD95 Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated - bs-0215R-A555 from Bioss
|
||||||||||
CD95 Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated - bs-0215R-A647 from Bioss
|
||||||||||
CD95 Polyclonal Antibody, Cy3 Conjugated - bs-0215R-Cy3 from Bioss
|
||||||||||
CD95 Polyclonal Antibody, Cy5 Conjugated - bs-0215R-Cy5 from Bioss
|
||||||||||
CD95 Polyclonal Antibody, Cy5.5 Conjugated - bs-0215R-Cy5.5 from Bioss
|
||||||||||
CD95 Polyclonal Antibody, Cy7 Conjugated - bs-0215R-Cy7 from Bioss
|
||||||||||
CD95 Polyclonal Antibody, FITC Conjugated - bs-0215R-FITC from Bioss
|
||||||||||
CD95 Polyclonal Antibody, Biotin Conjugated - bs-0215R-Biotin from Bioss
|
||||||||||
CD95 Polyclonal Antibody, HRP Conjugated - bs-0215R-HRP from Bioss
|
||||||||||
CD95 antibody - orb18095 from Biorbyt
|
||||||||||
FAS Antibody (OABF00100) - OABF00100 from Aviva Systems Biology
|
||||||||||
CD95 antibody - 10R-6452 from Fitzgerald
|
||||||||||
CD95 antibody (biotin) - 61R-1542 from Fitzgerald
|
||||||||||
CD95 antibody (PE) - 61R-1287 from Fitzgerald
|
||||||||||
Anti -Fas (CD95, APO-1, AI196731, Apo-1 antigen, Apoptosis-mediating surface antigen FAS,Apt1, APT1, FASLG receptor, lpr, TNFR6, Tnfrsf6, Tumor necrosis factor receptorsuperfamily member 6) - C2442-32L from USBiological Life Science
|
||||||||||
CD95 antibody - orb42246 from Biorbyt
|