Fas

Gene Symbol	Fas
Entrez Gene	14102
Alt Symbol	AI196731, APO1, APT1, CD95, TNFR6, Tnfrsf6, lpr
Species	Mouse
Gene Type	protein-coding
Description	Fas (TNF receptor superfamily member 6)
Other Description	FASLG receptor|Fas (TNF receptor superfamily member)|Fas antigen|apo-1 antigen|apoptosis-mediating surface antigen FAS|lymphoproliferation|tumor necrosis factor receptor superfamily member 6
Swissprots	Q9DCQ1 Q6GT31 P25446
Accessions	AAB25700 AAG02410 AAK27371 AAY51770 AAY51771 AAY51772 AAY51773 AAY51774 CAC00638 EDL41748 P25446 AK002590 BAB22211 AK086933 BAC39766 BC061160 AAH61160 BY348234 DQ846748 ABI24112 DQ846749 ABI24113 L15352 L15353 L25336 M83649 AAA37593 XM_011247141 XP_011245443 NM_001146708 NP_001140180 NM_007987 NP_032013
Function	Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death- inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS- mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both (By similarity). {ECO:0000250}.
Subcellular Location	Membrane; Single-pass type I membrane protein.
Tissue Specificity	Detected in various tissues including thymus, liver, lung, heart, and adult ovary.
Top Pathways	Apoptosis, Proteoglycans in cancer, Non-alcoholic fatty liver disease (NAFLD), p53 signaling pathway, TNF signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Mouse Fas ELISA Kit - RAB0784 from Sigma-Aldrich Category ELISA Kit Prices $637.00 Sizes 1 kt

Human Fas ELISA Kit - RAB0176 from Sigma-Aldrich Category ELISA Kit Prices $423.50 Sizes 1 kt

Human Fas ELISA Kit - RAB0177 from Sigma-Aldrich Category ELISA Kit Prices $423.50 Sizes 1 kt

Mouse CD95 ELISA kit - orb79006 from Biorbyt Category ELISA Kit Prices $740.00, $1,258.00, $2,678.00 Sizes 96 well, 192 assays, 480 assays

Factor Related Apoptosis (FAS), Mouse, ELISA Kit - SEA030Mu from ARP American Research Products Category ELISA Kit Prices $596.00 Sizes 96 t Sensitivity 10.2pg/mL Range 31.2-2,000pg/mL

Factor-related Apoptosis, FAS, Mouse, ELISA Kit - CSB-E04543m from ARP American Research Products Category ELISA Kit Prices $495.00, $695.00, $696.00, $699.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t Sensitivity 0.156 ng/ml Range 0.625 ng/ml-40 ng/ml

Fas (Mouse) ELISA Kit - KA2104 from Acris Antibodies Category ELISA Kit Prices $650.00 Sizes 1 kit

Mouse SFAS/Apo-1 ELISA Kit - MS0261 from NeoScientific Category ELISA Kit Prices $495.00 Sizes 96 t

CD95, ELISA Kit - MBS824697 from MyBioSource Category ELISA Kit Prices $470.00 Sizes 96 tests Sensitivity 3 pg/ml Range 31.2 pg/ml - 2000 pg/ml

Fas (TNF receptor superfamily, member 6) , ELISA Kit - MBS705075 from MyBioSource Category ELISA Kit Prices $250.00, $495.00, $710.00, $2,705.00, $5,145.00 Sizes 24 -strip-wells (Limit 1), 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.156 ng/ml Range 0.625 ng/ml-40 ng/ml

FASL, ELISA Kit - MBS177121 from MyBioSource Category ELISA Kit Prices $455.00 Sizes 1x96 wells Sensitivity < 10pg/ml Range 31.2pg/ml-2000pg/ml

Mouse CD95 ELISA Kit - CEK1437 from Cohesion Biosciences Category ELISA Kit Prices $360.00 Sizes 96 t Sensitivity 3 pg/ml Range 31.2 pg/ml - 2000 pg/ml

Mouse FASL PicoKine™ ELISA Kit EK0338 - EK0338 from Boster Bio Category ELISA Kit Prices $399.00 Sizes 1 kit Sensitivity <10pg/ml Range 31.2pg/ml-2000pg/ml *This assay range is determined using common samples. For samples with low target protein concentrations, users can adjust the standard curve to extend the lower limit of assay range.

Mouse Factor-related Apoptosis,FAS ELISA Kit - CSB-E04543m from Cusabio Category ELISA Kit Sensitivity 0.156 ng/ml. Range 0.625 ng/ml-40 ng/ml

ELISA Kit for Factor Related Apoptosis (FAS) - SEA030Mu from Cloud-clone Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 10.2pg/mL. Range 31.25-2000pg/mL The standard curve concentrations used for the ELISA's were 2000pg/mL, 1000pg/mL, 500pg/mL, 250pg/mL, 125pg/mL, 62.5pg/mL, 31.25pg/mL

CLIA Kit for Factor Related Apoptosis (FAS) - SCA030Mu from Cloud-clone Category CLIA Kit Sensitivity The minimum detectable dose of this kit is typically less than .

FASLG - KBB-280 from Nordic BioSite Sensitivity <10pg/ml Range 31.2pg/ml-2000pg/ml

Mouse FAS/CD95(Factor Related Apoptosis) ELISA Kit - E-EL-M0484 from Iwai North America Inc. Category ELISA Kit Prices $580.00 Sizes 1 kit Sensitivity 18.75 pg/mL Range 31.25~2000 pg/mL

Mouse Bcl-2 (B-Cell Leukemia/Lymphoma 2) CLIA Kit - E-CL-M0130 from Iwai North America Inc. Category CLIA Kit Prices $722.50 Sizes 1 kit Sensitivity 9.375pg/mL Range 15.625-1000pg/mL

Mouse CD95 ELISA kit - abx050039 from Abbexa Category ELISA Kit Sensitivity < 3 pg/ml Range 31.2 pg/ml - 2000 pg/ml

Mouse CD95 ELISA Kit - abx056436 from Abbexa Category ELISA Kit

FAS - KBB-352 from Nordic BioSite Sensitivity <3pg/ml Range 31.2pg/ml-2000pg/ml

Mouse CD95 ELISA kit - orb50156 from Biorbyt Category ELISA Kit Prices $502.00 Sizes 96 well Sensitivity < 3pg/ml Range 31.2pg/ml-2000pg/ml

Mouse CD95 ELISA Kit - orb138052 from Biorbyt Category ELISA Kit Prices $578.00 Sizes 96 well Sensitivity < 10pg/ml Range 31.2pg/ml-2000pg/ml

Mouse Tumor necrosis factor receptor superfamily member 6 ELISA Kit - EKE51597 from Biomatik Category ELISA Kit Prices $616.40, $2,619.70, $4,931.20 Sizes 96 t, 5x96t, 10x96t Range 78-5000 pg/mL

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