WASF1

Gene Symbol WASF1
Entrez Gene 8936
Alt Symbol SCAR1, WAVE, WAVE1
Species Human
Gene Type protein-coding
Description WAS protein family, member 1
Other Description WASP family protein member 1|homology of dictyostelium scar 1|protein WAVE-1|verprolin homology domain-containing protein 1|wiskott-Aldrich syndrome protein family member 1
Swissprots Q5SZK7 Q92558 E1P5F2
Accessions CAC38904 CAC43533 EAW48325 EAW48326 EAW48327 EAW48328 EAW48329 EAW48330 Q92558 AF134303 AAD33052 AI928895 AK097838 BC044591 AAH44591 BC068546 BG719023 BI461486 D87459 BAA13399 XM_005267203 XP_005267260 XM_005267204 XP_005267261 XM_005267205 XP_005267262 XM_005267206 XP_005267263 XM_005267207 XP_005267264 XM_011536233 XP_011534535 XM_011536234 XP_011534536 XM_011536235 XP_011534537 NM_001024934 NP_001020105 NM_001024935 NP_001020106 NM_001024936 NP_001020107 NM_003931 NP_003922
Function Downstream effector molecule involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton. Promotes formation of actin filaments. Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex.
Subcellular Location Cytoplasm, cytoskeleton. Cell junction, synapse {ECO:0000250}. Note=Dot-like pattern in the cytoplasm. Concentrated in Rac-regulated membrane-ruffling areas.
Tissue Specificity Highly expressed in brain. Lowly expressed in testis, ovary, colon, kidney, pancreas, thymus, small intestine and peripheral blood.
Top Pathways Adherens junction, Fc gamma R-mediated phagocytosis, Bacterial invasion of epithelial cells, Salmonella infection, Choline metabolism in cancer

WAVE (F-10) - sc-365165 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
WAVE (F-10): sc-365165. Western blot analysis of WAVE expression in IMR-32 (A) and MOLT-4 (B) whole cell lysates.

WAVE (H-180) - sc-5557 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
WAVE (H-180): sc-5557. Western blot analysis of WAVE3 expression in MOLT-4 whole cell lysate.

WAVE1 (B-8) - sc-271506 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
WAVE1 (B-8): sc-271506. Western blot analysis of WAVE1 expression in mouse brain tissue extract.

WAVE1 (C-17) - sc-10390 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
WAVE1 (C-17): sc-10390. Western blot analysis of WAVE1 expression in rat (A) and mouse (B) brain extracts.

WAVE1 (E-2) - sc-271507 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
WAVE1 (E-2): sc-271507. Western blot analysis of WAVE1 expression in non-transfected: sc-117752 (A) and mouse WAVE1 transfected: sc-124596 (B) 293T whole cell lysates and mouse brain tissue extract (C).

WAVE1 (L-19) - sc-10388 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
WAVE1 (L-19): sc-10388. Western blot analysis of WAVE1 expression in mouse brain extract.

WAVE1 (A-16) - sc-10389 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

WAVE1 (30) - sc-136120 from Santa Cruz Biotechnology

Prices $279.00
Sizes 50 µg/0.5 ml
Host Mouse
Clonality Monoclonal
WAVE1 (30): sc-136120. Western blot analysis of WAVE1 expression in rat cerebrum tissue extract.

Anti-WAVE 1 (phospho Y125) antibody - ab59280 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Ab59280 at 1/50 dilution staining human colon carcinoma without (left) and with (right) immunizing peptide; paraffin embedded.

Anti-WAVE 1 antibody - ab59281 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of paraffin-embedded human colon carcinoma tissue using ab59281 at a dilution of 1/50. Left hand image - without immunizing peptide; right hand image - with immunizing peptide.

Anti-WAVE 1 antibody [EPR15021] - N-terminal - ab185546 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR15021
All lanes : Anti-WAVE 1 antibody [EPR15021] - N-terminal (ab185546) at 1/10000 dilutionLane 1 : U87-MG cell lysateLane 2 : K562 cell lysateLane 3 : 293T cell lysateLysates/proteins at 20 µg per lane.SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/1000 dilution

Anti-WAVE 1 antibody [S91-36] - ab106516 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone S91-36

Anti-WASF1 / WAVE Antibody (aa91-140) - LS-C117730 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
IHC of paraffin-embedded human brain tissue, using WAVE1 (Ab-125) Antibody. The picture on the right is treated with the synthesized peptide.

Anti-WASF1 / WAVE Antibody - LS-C18542 from LifeSpan Bioscience

Prices $530.00
Sizes 200 µl
Host Mouse
Clonality Monoclonal

Anti-WASF1 / WAVE Antibody (aa177-190) - LS-C186633 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Anti-WASF1 / WAVE Antibody (aa477-498, clone S91-36, Atto 390) - LS-C228391 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal
Clone S91-36

Anti-WASF1 / WAVE Antibody (aa477-498, clone S91-36, Atto 565) - LS-C228392 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal
Clone S91-36

Anti-WASF1 / WAVE Antibody (aa477-498, clone S91-36, Atto 488) - LS-C228393 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal
Clone S91-36

Anti-WASF1 / WAVE Antibody (aa477-498, clone S91-36, APC) - LS-C228395 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal
Clone S91-36

Anti-WASF1 / WAVE Antibody (aa477-498, clone S91-36, Biotin) - LS-C228396 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal
Clone S91-36

Anti-WASF1 / WAVE Antibody (aa477-498, clone S91-36, FITC) - LS-C228397 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal
Clone S91-36

Anti-WASF1 / WAVE Antibody (aa477-498, clone S91-36, PE-Atto 594) - LS-C228399 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal
Clone S91-36

Anti-WASF1 / WAVE Antibody (aa477-498, clone S91-36, PerCP) - LS-C228400 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal
Clone S91-36

Anti-WASF1 / WAVE Antibody (aa477-498, clone S91-36, RPE) - LS-C228402 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal
Clone S91-36

Anti-WASF1 / WAVE Antibody (aa477-498, clone S91-36, SA) - LS-C228403 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal
Clone S91-36
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