CFI

Gene Symbol CFI
Entrez Gene 3426
Alt Symbol AHUS3, ARMD13, C3BINA, C3b-INA, FI, IF, KAF
Species Human
Gene Type protein-coding
Description complement factor I
Other Description C3B/C4B inactivator|C3b-inactivator|Konglutinogen-activating factor|complement component I|complement control protein factor I|complement factor I heavy chain|light chain of factor I
Swissprots P05156 O60442
Accessions AAC08733 EAX06250 EAX06251 EAX06252 P05156 AK122686 AK290625 BAF83314 AK299232 BAG61264 BC005275 BC020718 AAH20718 BM955734 BP235907 DC392360 J02770 AAA52455 N63668 Y00318 CAA68416 XM_005262975 XP_005263032 XM_005262976 XP_005263033 XM_006714209 XP_006714272 XM_006714210 XP_006714273 XM_011531920 XP_011530222 NM_000204 NP_000195
Function Responsible for cleaving the alpha-chains of C4b and C3b in the presence of the cofactors C4-binding protein and factor H respectively.
Subcellular Location Secreted, extracellular space.
Tissue Specificity Plasma.
Top Pathways Complement and coagulation cascades, Staphylococcus aureus infection

Factor I (T-19) - sc-69470 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Factor I (T-19): sc-69470. Western blot analysis of Factor I expression in Jurkat (A), HeLa (B), U-251-MG (C) and U-698-M (D) whole cell lysates.

Factor I (KT22) - sc-101481 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal

Factor I (3D6) - sc-57507 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal

Factor I (3H466) - sc-71089 from Santa Cruz Biotechnology

Prices $279.00
Sizes 2000 µl supernatant
Host Mouse
Clonality Monoclonal

Anti-Factor I antibody - ab8843 from Abcam

Prices $378.00
Sizes 1 ml
Host Sheep
Clonality Polyclonal
ICC/IF image of ab8843 stained HepG2 cells. The cells were 4% formaldehyde fixed (10 min) and then incubated in 1%BSA / 10% normal donkey serum / 0.3M glycine in 0.1% PBS-Tween for 1h to permeabilise the cells and block non-specific protein-protein interactions. The cells were then incubated with the antibody ab8843 at 1/200 dilution overnight at +4°C. The secondary antibody (pseudo-colored green) was Alexa Fluor® 488 donkey anti- Sheep (ab150177) IgG used at a 1/1000 dilution for 1h. Alexa Fluor® 594 WGA was used to label plasma membranes (pseudo-colored red) at a 1/200 dilution for 1h at room temperature. DAPI was used to stain the cell nuclei (pseudo-colored blue) at a concentration of 1.43µM for 1hour at room temperature.

Anti-Factor I antibody - ab110060 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Factor I antibody (ab110060) at 1/500 dilutionLane 1 : Jurkat cell lysateLane 2 : Jurkat cell lysate with immunizing peptide at 10 µgLysates/proteins at 30 µg per lane.

Anti-Factor I antibody - ab183091 from Abcam

Host Sheep
Clonality Polyclonal

Anti-Factor I antibody - ab181750 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of paraffin embedded Human skin tissue labeling Factor I with ab181750 at 1/50 dilution.

Anti-Factor I antibody - ab82703 from Abcam

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-Factor I antibody - ab90546 from Abcam

Prices $376.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Anti-Factor I antibody (ab90546) at 1 µg/ml + Human kidney lysate at 50 µg

Anti-Factor I antibody - ab125440 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-Factor I antibody (ab125440) at 1 µg/ml + HeLa cell lysate at 10 µg

Anti-Factor I antibody [3D6] - ab52244 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 3D6

Anti-Factor I antibody [OX-21] - ab115312 from Abcam

Prices $381.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone OX-21
ab115312 at 20ug/ml staining Factor I in Human colon (vessels) tissue by immunohistochemistry (FFPE). After primary incubation, slides were incubated with biotinylated anti-mouse IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.

Anti-Factor I antibody [OX21] - ab23307 from Abcam

Prices $359.00
Sizes 1 ml
Host Mouse
Clonality Monoclonal
Clone OX21

Anti-CFI / Complement Factor I Antibody - LS-C22344 from LifeSpan Bioscience

Prices $405.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-CFI / Complement Factor I Antibody - LS-C23337 from LifeSpan Bioscience

Prices $465.00
Sizes 5 ml
Host Mouse
Clonality Monoclonal

Anti-CFI / Complement Factor I Antibody - LS-C128327 from LifeSpan Bioscience

Prices $405.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-CFI / Complement Factor I Antibody - LS-C125390 from LifeSpan Bioscience

Host Sheep
Clonality Polyclonal

Anti-CFI / Complement Factor I Antibody (clone OX-21, Biotin) - LS-C62861 from LifeSpan Bioscience

Prices $255.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone OX-21

Anti-CFI / Complement Factor I Antibody - LS-C45168 from LifeSpan Bioscience

Prices $350.00
Sizes 5 ml
Host Mouse
Clonality Monoclonal

Anti-CFI / Complement Factor I Antibody - LS-C123314 from LifeSpan Bioscience

Prices $665.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-CFI / Complement Factor I Antibody - LS-C147802 from LifeSpan Bioscience

Prices $285.00
Sizes 1 ml
Host Sheep
Clonality Polyclonal

Anti-CFI / Complement Factor I Antibody (clone OX-21, FITC) - LS-C62862 from LifeSpan Bioscience

Prices $265.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone OX-21

Anti-CFI / Complement Factor I Antibody (Internal) - LS-C153419 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-CFI / Complement Factor I Antibody (clone KT22) - LS-C193512 from LifeSpan Bioscience

Prices $345.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone KT22
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