Gene Symbol | SOX3 |
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Entrez Gene | 6658 |
Alt Symbol | GHDX, MRGH, PHP, PHPX, SOXB |
Species | Human |
Gene Type | protein-coding |
Description | SRY (sex determining region Y)-box 3 |
Other Description | transcription factor SOX-3 |
Swissprots | Q9NP49 P35714 Q5JWI3 P41225 |
Accessions | AAF73059 CAA50465 EAW88422 P41225 AK313820 BC093863 AAH93863 BC093865 AAH93865 X65665 CAA46616 X71137 CAA50467 NM_005634 NP_005625 |
Function | Transcription factor required during the formation of the hypothalamo-pituitary axis. May function as a switch in neuronal development. Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation. Required also within the pharyngeal epithelia for craniofacial morphogenesis. Controls a genetic switch in male development. Is necessary for initiating male sex determination by directing the development of supporting cell precursors (pre-Sertoli cells) as Sertoli rather than granulosa cells (By similarity). {ECO:0000250}. |
Subcellular Location | Nucleus. |
Sox-3 (C-20) - sc-17324 from Santa Cruz Biotechnology
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Sox-3 (H-135) - sc-20089 from Santa Cruz Biotechnology
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Sox-3 (16-C2) - sc-101155 from Santa Cruz Biotechnology
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Sox-3 (J-23) - sc-134023 from Santa Cruz Biotechnology
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Anti-SOX3 antibody - ab42471 from Abcam
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Anti-SOX3 antibody - ab170778 from Abcam
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Anti-SOX3 antibody - ab55795 from Abcam
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Anti-SOX3 antibody - ab183606 from Abcam
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Anti-SOX3 Antibody (aa283-295) - LS-C10298 from LifeSpan Bioscience
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Anti-SOX3 Antibody (N-Terminus) - LS-C31059 from LifeSpan Bioscience
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Anti-SOX3 Antibody (aa173-204, AP) - LS-C270017 from LifeSpan Bioscience
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Anti-SOX3 Antibody (aa173-204, APC) - LS-C270018 from LifeSpan Bioscience
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Anti-SOX3 Antibody (aa173-204, Biotin) - LS-C270019 from LifeSpan Bioscience
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Anti-SOX3 Antibody (C-Terminus) - LS-C31061 from LifeSpan Bioscience
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Anti-SOX3 Antibody (aa173-204, FITC) - LS-C270022 from LifeSpan Bioscience
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Anti-SOX3 Antibody (aa173-204, Azide-free, HRP) - LS-C270023 from LifeSpan Bioscience
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Anti-SOX3 Antibody (aa173-204, PE) - LS-C270024 from LifeSpan Bioscience
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Anti-SOX3 Antibody (aa80-129) IHC-plus⢠- LS-B1569 from LifeSpan Bioscience
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Anti-SOX3 Antibody (aa413-427) IHC-plus⢠- LS-B8332 from LifeSpan Bioscience
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Anti-SOX3 Antibody (aa173-204) - LS-C325285 from LifeSpan Bioscience
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Anti-SOX3 Antibody (clone 1F2) - LS-C198244 from LifeSpan Bioscience
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Anti-SOX3 Antibody (aa375-446, Azide-free) - LS-C328725 from LifeSpan Bioscience
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Anti-SOX3 Antibody (aa215-264) - LS-C109773 from LifeSpan Bioscience
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Anti-SOX3 Antibody (aa166-196) - LS-C161402 from LifeSpan Bioscience
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Anti-SOX3 Antibody (aa189-218) - LS-C161401 from LifeSpan Bioscience
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