Gene Symbol | SOX3 |
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Entrez Gene | 6658 |
Alt Symbol | GHDX, MRGH, PHP, PHPX, SOXB |
Species | Human |
Gene Type | protein-coding |
Description | SRY (sex determining region Y)-box 3 |
Other Description | transcription factor SOX-3 |
Swissprots | Q9NP49 P35714 Q5JWI3 P41225 |
Accessions | AAF73059 CAA50465 EAW88422 P41225 AK313820 BC093863 AAH93863 BC093865 AAH93865 X65665 CAA46616 X71137 CAA50467 NM_005634 NP_005625 |
Function | Transcription factor required during the formation of the hypothalamo-pituitary axis. May function as a switch in neuronal development. Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation. Required also within the pharyngeal epithelia for craniofacial morphogenesis. Controls a genetic switch in male development. Is necessary for initiating male sex determination by directing the development of supporting cell precursors (pre-Sertoli cells) as Sertoli rather than granulosa cells (By similarity). {ECO:0000250}. |
Subcellular Location | Nucleus. |
SOX3 Antibody Blocking Peptide - LS-E993 from LifeSpan Bioscience
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SOX3 Antibody Blocking Peptide - LS-E1405 from LifeSpan Bioscience
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SOX3 Antibody Blocking Peptide - LS-E27374 from LifeSpan Bioscience
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SOX3 Antibody Blocking Peptide - LS-E11747 from LifeSpan Bioscience
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SOX3 Antibody Blocking Peptide - LS-E11748 from LifeSpan Bioscience
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SOX3 Antibody Blocking Peptide - LS-E13912 from LifeSpan Bioscience
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SOX3-Antibody-Center-Blocking-peptide - BP11445c from Abgent, a WuXi AppTec company
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SOX3-Antibody-Center-P204-Blocking-peptide - BP12071c from Abgent, a WuXi AppTec company
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SOX3 blocking peptide - GTX88078-PEP from GeneTex
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SOX3 Peptide - AC21-2199-P from Abcore
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SOX3 Peptide - 42-590P from ProSci
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Recombinant Human Transcription factor SOX-3(SOX3) - CSB-YP022429HU CSB-EP022429HU CSB-BP022429HU CSB-MP022429HU from Cusabio
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SOX3, Peptide - MBS427355 from MyBioSource
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SOX3 Peptide, Human - M34GP14918H from Creative Peptides
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SOX3 Recombinant Protein Antigen - NBP2-57856PEP from Novus Biologicals
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SOX3 Recombinant Protein Antigen - NBP2-55569PEP from Novus Biologicals
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SOX3 Recombinant Protein Antigen - NBP2-59060PEP from Novus Biologicals
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