CATSPER3

Gene Symbol CATSPER3
Entrez Gene 347732
Alt Symbol CACRC
Species Human
Gene Type protein-coding
Description cation channel, sperm associated 3
Other Description ca(v)-like protein|calcium channel repeat containing 1|cation channel sperm-associated protein 3|one-repeat calcium channel-like protein|putative ion channel CatSper3
Swissprots Q86XS6 Q86XQ3
Accessions EAW62228 Q86XQ3 AF432876 AAO85416 AK292427 BAF85116 AW008956 AY156951 AAO13012 BC101692 AAI01693 BC110384 AAI10385 BI827754 BN000272 CAE30476 NM_178019 NP_821138
Function Voltage-gated calcium channel that plays a central role in calcium-dependent physiological responses essential for successful fertilization, such as sperm hyperactivation, acrosome reaction and chemotaxis towards the oocyte. Activated by extracellular progesterone and prostaglandins following the sequence: progesterone > PGF1-alpha = PGE1 > PGA1 > PGE2 >> PGD2. The primary effect of progesterone activation is to shift voltage dependence towards more physiological, negative membrane potentials; it is not mediated by metabotropic receptors and second messengers. Sperm capacitation enhances the effect of progesterone by providing additional negative shift. Also activated by the elevation of intracellular pH. {ECO:0000269|PubMed:21412338, ECO:0000269|PubMed:21412339}.
Subcellular Location Cell projection, cilium, flagellum membrane; Multi-pass membrane protein. Note=Specifically located in the principal piece of sperm tail.
Tissue Specificity Testis-specific. {ECO:0000269|PubMed:12646162, ECO:0000269|PubMed:12932298, ECO:0000269|PubMed:17347248}.

CatSper3 CRISPR/Cas9 KO Plasmid (h) - sc-415636 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CatSper3 HDR Plasmid (h) - sc-415636-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CatSper3 Double Nickase Plasmid (h) - sc-415636-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CatSper3 Double Nickase Plasmid (h2) - sc-415636-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CatSper3 CRISPR Activation Plasmid (h) - sc-415636-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CatSper3 CRISPR Activation Plasmid (h2) - sc-415636-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CatSper3 Lentiviral Activation Particles (h) - sc-415636-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CatSper3 Lentiviral Activation Particles (h2) - sc-415636-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CatSper3 siRNA (h) - sc-72811 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CatSper3 shRNA Plasmid (h) - sc-72811-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CatSper3 shRNA (h) Lentiviral Particles - sc-72811-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU021111 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN5398 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND5398 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

CATSPER3 siRNA (Human) - CRJ7514 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

CATSPER3 RNAi - H00347732-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

CATSPER3 - MBS8228606 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human CATSPER3 (NM_178019.2) - SHH255165 from Creative biogene

Category siRNA
Species Reactivities Human

CATSPER3 shRNA Plasmid (Human) - CHJ7514 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

CATSPER3 miRNA 3'UTR clone - MiUTR3H-10421 from Creative biogene

Species Reactivities Human
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