SERPINB3

Gene Symbol	SERPINB3
Entrez Gene	6317
Alt Symbol	HsT1196, SCC, SCCA-1, SCCA-PD, SCCA1, T4-A
Species	Human
Gene Type	protein-coding
Description	serpin peptidase inhibitor, clade B (ovalbumin), member 3
Other Description	protein T4-A|serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 3|serpin B3|squamous cell carcinoma antigen 1
Swissprots	Q9BYF8 Q86W04 Q8IWL4 B3W5Y6 A6NDM2 Q8IXI3 Q86VF3 P29508 Q53H28 B2RBT5 Q96J21 Q53YB5
Accessions	AAA86316 AAA86317 BAB21524 EAW63156 EAW63157 P29508 AB046399 BAB40772 AF428135 AAQ04218 AF428136 AAQ04219 AF428137 AAQ04220 AF428138 AAQ04221 AF428139 AAQ04222 AF461146 AAQ04770 AJ515706 CAD56658 AK222746 BAD96466 AK222753 BAD96473 AK307261 AK308383 AK310948 AK314805 BAG37332 AY190327 AAO11731 AY245778 AAO92269 AY245781 AAO92272 BC005224 AAH05224 BC008483 BT006748 AAP35394 DB229922 DQ890560 ABM92177 DQ893722 ABM84648 EU852041 ACF21012 S66896 AAB20405 U19556 AAA97552 NM_006919 NP_008850
Function	May act as a papain-like cysteine protease inhibitor to modulate the host immune response against tumor cells. Also functions as an inhibitor of UV-induced apoptosis via suppression of the activity of c-Jun NH(2)-terminal kinase (JNK1). {ECO:0000269|PubMed:19166818}.
Subcellular Location	Cytoplasm {ECO:0000269|PubMed:10956412, ECO:0000269|PubMed:14970861}. Note=Seems to also be secreted in plasma by cancerous cells but at a low level.
Tissue Specificity	Squamous cells. Expressed in some hepatocellular carcinoma (at protein level). {ECO:0000269|PubMed:14970861}.
Top Pathways	Amoebiasis

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

SERPINB3-Over-expression-Lysate - LY10865a from Abgent, a WuXi AppTec company Category Cell Lysate Prices $325.00 Sizes 100 µg

SERPINB3 293T Cell Transient Overexpression Lysate(Denatured) - H00006317-T01 from Acris Antibodies Category Cell Lysate Prices $320.00 Sizes 100 µl

SERPINB3 293T Cell Transient Overexpression Lysate(Denatured) - H00006317-T02 from Acris Antibodies Category Cell Lysate Prices $320.00 Sizes 100 µl

SERPINB3 overexpression lysate - LY416321 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

SERPINB3 293 Cell Lysate - 407632 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg

Serpin B3/SCCA1 Overexpression Lysate (Denatured) - H00006317-T01 from Novus Biologicals Category Cell Lysate Prices $279.00 Sizes 100 µl

Serpin B3/SCCA1 Overexpression Lysate (Denatured) - H00006317-T02 from Novus Biologicals Category Cell Lysate Prices $299.00 Sizes 100 µl Species Human

Serpin B3/SCCA1 Overexpression Lysate (Native) - NBL1-15846 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

SERPINB3 Over-expression Lysate Product - GWB-ED39F8 from Genway Biotech Category Cell Lysate Prices $346.00 Sizes 100 µg Species Human

Human SerpinB3 / SCCA-1 Insect Cell Lysate (WB positive control) - 13218-H07BL-300 from Sino Biological Category Cell Lysate Prices $195.00 Sizes 300 µg Species Human

Serpin B3/SCCA1 Overexpression Lysate (Denatured) - H00006317-T04 from Novus Biologicals Category Cell Lysate Prices $299.00 Sizes 100 µl

Serpin B3/SCCA1 Overexpression Lysate (Denatured) - H00006317-T03 from Novus Biologicals Category Cell Lysate Prices $299.00 Sizes 100 µl

Human SERPINB3 Baculovirus-Insect Cells Transfected Lysate (positive control) (denatured) - orb175152 from Biorbyt Category Cell Lysate Prices $604.00 Sizes 300 μg Species Human

Panoply™ Human SERPINB3 Knockdown Stable Cell Line - CSC-DC014050 from Creative biogene Category Cell Line Species Human

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