SERPINB3

Gene Symbol SERPINB3
Entrez Gene 6317
Alt Symbol HsT1196, SCC, SCCA-1, SCCA-PD, SCCA1, T4-A
Species Human
Gene Type protein-coding
Description serpin peptidase inhibitor, clade B (ovalbumin), member 3
Other Description protein T4-A|serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 3|serpin B3|squamous cell carcinoma antigen 1
Swissprots Q9BYF8 Q86W04 Q8IWL4 B3W5Y6 A6NDM2 Q8IXI3 Q86VF3 P29508 Q53H28 B2RBT5 Q96J21 Q53YB5
Accessions AAA86316 AAA86317 BAB21524 EAW63156 EAW63157 P29508 AB046399 BAB40772 AF428135 AAQ04218 AF428136 AAQ04219 AF428137 AAQ04220 AF428138 AAQ04221 AF428139 AAQ04222 AF461146 AAQ04770 AJ515706 CAD56658 AK222746 BAD96466 AK222753 BAD96473 AK307261 AK308383 AK310948 AK314805 BAG37332 AY190327 AAO11731 AY245778 AAO92269 AY245781 AAO92272 BC005224 AAH05224 BC008483 BT006748 AAP35394 DB229922 DQ890560 ABM92177 DQ893722 ABM84648 EU852041 ACF21012 S66896 AAB20405 U19556 AAA97552 NM_006919 NP_008850
Function May act as a papain-like cysteine protease inhibitor to modulate the host immune response against tumor cells. Also functions as an inhibitor of UV-induced apoptosis via suppression of the activity of c-Jun NH(2)-terminal kinase (JNK1). {ECO:0000269|PubMed:19166818}.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:10956412, ECO:0000269|PubMed:14970861}. Note=Seems to also be secreted in plasma by cancerous cells but at a low level.
Tissue Specificity Squamous cells. Expressed in some hepatocellular carcinoma (at protein level). {ECO:0000269|PubMed:14970861}.
Top Pathways Amoebiasis

SCCA1 CRISPR/Cas9 KO Plasmid (h) - sc-403601 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

SCCA1 HDR Plasmid (h) - sc-403601-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SCCA1 Double Nickase Plasmid (h) - sc-403601-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SCCA1 Double Nickase Plasmid (h2) - sc-403601-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SCCA1 CRISPR Activation Plasmid (h) - sc-403601-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

SCCA1 CRISPR Activation Plasmid (h2) - sc-403601-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

SCCA1 Lentiviral Activation Particles (h) - sc-403601-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SCCA1 Lentiviral Activation Particles (h2) - sc-403601-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SCCA1 siRNA (h) - sc-40950 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

SCCA1 shRNA Plasmid (h) - sc-40950-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

SCCA1 shRNA (h) Lentiviral Particles - sc-40950-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

SCCA1/2 siRNA (h) - sc-44087 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

SCCA1/2 shRNA Plasmid (h) - sc-44087-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

SCCA1/2 shRNA (h) Lentiviral Particles - sc-44087-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Serpin B3/SCCA1 RNAi - H00006317-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU116981 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN19143 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND19143 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

SERPINB3 siRNA (Human) - CRH4255 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

SERPINB3 - MBS8239497 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

Human SERPINB3 siRNA - orb264757 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

SERPINB3 shRNA Plasmid (Human) - CHH4255 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

SERPINB3 miRNA 3'UTR clone - MiUTR3H-03433 from Creative biogene

Species Reactivities Human
Search more