Gene Symbol | TRIM32 |
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Entrez Gene | 22954 |
Alt Symbol | BBS11, HT2A, LGMD2H, TATIP |
Species | Human |
Gene Type | protein-coding |
Description | tripartite motif containing 32 |
Other Description | 72 kDa Tat-interacting protein|E3 ubiquitin-protein ligase TRIM32|TAT-interactive protein, 72-KD|tripartite motif-containing 32|tripartite motif-containing protein 32|zinc finger protein HT2A|zinc-finger protein HT2A |
Swissprots | Q13049 Q9NQP8 |
Accessions | CAX86996 CAY39310 EAW87446 EAW87447 Q13049 AK314264 AX775779 CAE11589 BC003154 AAH03154 BI544919 BX091494 DN991209 DQ893081 ABM84007 DQ896342 ABM87341 U18543 AAA86474 XM_005251813 XP_005251870 XM_011518396 XP_011516698 XM_011518397 XP_011516699 XM_011518398 XP_011516700 NM_001099679 NP_001093149 NM_012210 NP_036342 |
Function | Has an E3 ubiquitin ligase activity. Ubiquitinates DTNBP1 (dysbindin) and promotes its degradation. May ubiquitinate BBS2. May play a significant role in mediating the biological activity of the HIV-1 Tat protein in vivo. Binds specifically to the activation domain of HIV-1 Tat and can also interact with the HIV-2 and EIAV Tat proteins in vivo. {ECO:0000269|PubMed:19349376, ECO:0000269|PubMed:22500027}. |
Subcellular Location | Cytoplasm. Note=Localized in cytoplasmic bodies, often located around the nucleus. |
Tissue Specificity | Spleen, thymus, prostate, testis, ovary, intestine, colon and skeletal muscle. {ECO:0000269|PubMed:11822024}. |
Top Pathways | Ubiquitin mediated proteolysis |
Human TRIM32 full length protein - ab161486 from Abcam
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Human TRIM32 protein fragment - ab161487 from Abcam
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HT2A / TRIM32 Antibody Blocking Peptide - LS-E11077 from LifeSpan Bioscience
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HT2A / TRIM32 Antibody Blocking Peptide - LS-E14046 from LifeSpan Bioscience
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Recombinant Human TRIM32 Protein - H00022954-P01 from Novus Biologicals
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TRIM32 Partial Recombinant Protein - H00022954-Q01 from Novus Biologicals
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Recombinant Human TRIM32 Protein - NBP1-98964 from Novus Biologicals
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TRIM32-Antibody-N-term-Blocking-peptide - BP13287a from Abgent, a WuXi AppTec company
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TRIM32 Blocking Peptide - 33R-3501 from Fitzgerald
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TRIM32 / HT2A - H00022954-P01-10 from Acris Antibodies
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TRIM32 / HT2A - H00022954-P01-25 from Acris Antibodies
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TRIM32 / HT2A - H00022954-Q01-10 from Acris Antibodies
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TRIM32 / HT2A - H00022954-Q01-25 from Acris Antibodies
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TRIM32 fusion protein - ag0401 from Proteintech Group
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Recombinant Human TRIM32, GST-tagged - TRIM32-198H from Creative Biomart
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TRIM32 protein-GST fusion - 009-001-U20 from Rockland Immunochemicals Inc
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TRIM32 protein-GST fusion - 009-001-U20S from Rockland Immunochemicals Inc
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Recombinant Human E3 ubiquitin-protein ligase TRIM32(TRIM32) - CSB-YP614389HU CSB-EP614389HU CSB-BP614389HU CSB-MP614389HU from Cusabio
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TRIM32 Protein - abx164288 from Abbexa
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TRIM32 / HT2A (transcript variant 1) - TP301289 from Acris Antibodies
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TRIM32 / HT2A (transcript variant 2) - TP323796 from Acris Antibodies
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TRIM32 Recombinant Protein Antigen - NBP2-13484PEP from Novus Biologicals
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TRIM32 Peptide, Human - M34GP16584H from Creative Peptides
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E3 ubiquitin-protein ligase TRIM32 (TRIM32), Recombinant Protein - MBS1375338 from MyBioSource
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