BIN2

Gene Symbol	BIN2
Entrez Gene	51411
Alt Symbol	BRAP-1
Species	Human
Gene Type	protein-coding
Description	bridging integrator 2
Other Description	breast cancer associated protein BRAP1|breast cancer-associated protein 1|bridging integrator-2
Swissprots	Q9UBW5 Q9UKN4 Q86VV0 Q9NWK4
Accessions	BAA88125 EAW58186 EAW58187 EAW58188 Q9UBW5 AB032698 BAA88108 AF146531 AAD54227 AK000783 BAA91376 AK093638 AK225911 AK300211 BAH13239 AK314304 BAG36957 BC047686 AAH47686 BG388638 BX281612 CB996605 DB035315 XM_005268957 XP_005269014 XM_005268958 XP_005269015 XM_011538452 XP_011536754 XM_011538453 XP_011536755 NM_001290007 NP_001276936 NM_001290008 NP_001276937 NM_001290009 NP_001276938 NM_016293 NP_057377
Function	Promotes cell motility and migration, probably via its interaction with the cell membrane and with podosome proteins that mediate interaction with the cytoskeleton. Modulates membrane curvature and mediates membrane tubulation. Plays a role in podosome formation. Inhibits phagocytosis. {ECO:0000269|PubMed:23285027}.
Subcellular Location	Cytoplasm. Cell projection, podosome membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cell cortex. Cell projection, phagocytic cup. Note=Associates with membranes enriched in phosphoinositides. Detected in the actin-rich cell cortex at the leading edge of migrating cells. Detected at podosomes, at an actin-rich ring-like structure.
Tissue Specificity	Detected in natural killer cells (at protein level). Highest level expression seen in spleen and peripheral blood leukocytes and is also expressed at high levels in thymus, colon and placenta, suggesting preferential expression in hematopoietic tissues. {ECO:0000269|PubMed:10903846, ECO:0000269|PubMed:23285027}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human BIN2 ELISA Kit (Sandwich ELISA) - LS-F8367 from LifeSpan Bioscience Category ELISA Kit Prices $720.00 Sizes 1 plate Sensitivity 0.112 ng/ml Range 0.313-20 ng/ml

Human Bridging Integrator 2 ELISA Kit - abx150840 from Abbexa Category ELISA Kit Sensitivity 0.112 ng/ml Range 0.313 ng/ml - 20 ng/ml

Bridging Integrator 2 (BIN2), Human, ELISA Kit - SEJ554Hu from ARP American Research Products Category ELISA Kit Prices $720.00 Sizes 96 t Sensitivity 0.112ng/mL Range 0.312-20ng/mL

Bridging Integrator 2, ELISA Kit - MBS057377 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Bridging Integrator 2, ELISA Kit - MBS054826 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Bridging Integrator 2, ELISA Kit - MBS075882 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Bridging Integrator 2, ELISA Kit - MBS088170 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Bridging Integrator 2, ELISA Kit - MBS048746 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Bridging Integrator 2, ELISA Kit - MBS093299 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Bridging Integrator 2, ELISA Kit - MBS092577 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Bridging Integrator 2 (BIN2), ELISA Kit - MBS2023131 from MyBioSource Category ELISA Kit Prices $380.00, $565.00, $765.00, $3,130.00, $5,670.00 Sizes 24 -strip-wells, 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity Typically less than 0.112ng/mL. Range 0.313-20ng/mL

ELISA Kit for Bridging Integrator 2 (BIN2) - SEJ554Hu from Uscn Life Science Inc. Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.112ng/mL. Range 0.313-20ng/mL The standard curve concentrations used for the ELISA’s were 20ng/mL, 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL

ELISA Kit for Bridging Integrator 2 (BIN2) - SEJ554Hu from Cloud-clone Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.112ng/mL. Range 0.313-20ng/mL The standard curve concentrations used for the ELISA's were 20ng/mL, 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL

Human Bridging Integrator 2 (BIN2) ELISA Kit - EKU02812 from Biomatik Category ELISA Kit Prices $735.00, $3,234.00, $5,880.00 Sizes 96 t, 5x96t, 10x96t Sensitivity 0.112 ng/mL Range 0.312-20 ng/mL

Bridging Integrator 2 (BIN2), Human, ELISA Kit - DL-BIN2-Hu from ARP American Research Products Category ELISA Kit Prices $655.00 Sizes 96 t Range 0.312-20 ng/mL

Human BIN2 ELISA Kit - abx572838 from Abbexa Category ELISA Kit Sensitivity 0.112 ng/ml Range 0.313 ng/ml - 20 ng/ml

Human BIN2 ELISA Kit - E005319 from Biobool Category ELISA Kit Sensitivity Typically less than 0.112ng/mL.

BIN2 ELISA Kit (Human) (OKCD01058) - OKCD01058 from Aviva Systems Biology Category ELISA Kit Prices $545.00 Sizes 96 wells Sensitivity < 0.112 ng/mL Range 0.312-20 ng/mL

Human Bridging integrator 2 (BIN2) ELISA Kit - AE61684HU from ARP American Research Products Category ELISA Kit Prices $549.00 Sizes 96 t Sensitivity 0.112 ng/mL Range 0.312-20 ng/mL

Bridging Integrator 2 (BIN2), ELISA Kit - MBS452478 from MyBioSource Category ELISA Kit Prices $415.00, $550.00, $2,425.00, $4,710.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity <0.112ng/mL Range 0.312-20ng/mL

Bridging Integrator 2 (BIN2), ELISA Kit - MBS9371301 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Search more