BSCL2

Gene Symbol	BSCL2
Entrez Gene	26580
Alt Symbol	GNG3LG, HMN5, PELD, SPG17
Species	Human
Gene Type	protein-coding
Description	Berardinelli-Seip congenital lipodystrophy 2 (seipin)
Other Description	Bernardinelli-Seip congenital lipodystrophy type 2 protein|seipin
Swissprots	Q96G97 Q567S1 Q9BSQ0 Q96SV1 G3XAE4
Accessions	ACA50720 CAF86927 CAI93437 EAW74070 EAW74071 EAW74072 EAW74073 EAW74074 EAW74075 EAW74076 EAW74077 EAW74078 EAW74080 EAW74081 Q96G97 AF052149 AK027524 BAB55175 AK075317 BAC11543 AK223606 BAD97326 AK225029 AK315423 BC004911 AAH04911 BC009866 BC012140 AAH12140 BC041640 AAH41640 BC093048 AAH93048 BG699373 BM763152 BP370169 CD107822 DB178846 DB296305 DQ575792 DQ584208 DQ893483 ABM84409 EU176769 ABW03570 NM_001122955 NP_001116427 NM_001130702 NP_001124174 NM_032667 NP_116056 NR_037948 NR_037949
Function	Is a regulator of lipid catabolism essential for adipocyte differentiation. May also be involved in the central regulation of energy homeostasis (By similarity). Necessary for correct lipid storage and lipid droplets maintenance; may play a tissue-autonomous role in controlling lipid storage in adipocytes and in preventing ectopic lipid droplet formation in non-adipose tissues. {ECO:0000250, ECO:0000269|PubMed:19278620, ECO:0000269|PubMed:21533227}.
Subcellular Location	Endoplasmic reticulum membrane {ECO:0000269|PubMed:14981520, ECO:0000269|PubMed:16574104, ECO:0000269|PubMed:18458148}; Multi-pass membrane protein {ECO:0000269|PubMed:14981520, ECO:0000269|PubMed:16574104, ECO:0000269|PubMed:18458148}.
Tissue Specificity	Expressed in motor neurons in the spinal cord and cortical neurons in the frontal lobe (at protein level). Highly expressed in brain, testis and adipose tissue. {ECO:0000269|PubMed:11479539, ECO:0000269|PubMed:18458148, ECO:0000269|PubMed:18585921}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human-BSCL2-cDNA-Clone - DC03326 from Abgent, a WuXi AppTec company Prices $537.30 Sizes 10 µg Species Human Accession BC012140

BSCL2 - MBS1277958 from MyBioSource Prices $175.00 Sizes 10ug plasmid + 200ul glycerol stock Species Human Accession BC012140

BSCL2 - MBS1269823 from MyBioSource Prices $175.00 Sizes 10ug plasmid + 200ul glycerol stock Species Human Accession BC009866

BSCL2 - MBS1269384 from MyBioSource Prices $175.00 Sizes 10ug plasmid + 200ul glycerol stock Species Human Accession BC004911

BSCL2 - MBS1275100 from MyBioSource Prices $175.00 Sizes 10ug plasmid + 200ul glycerol stock Species Human Accession BC041640

Human BSCL2 Gene ORF cDNA clone in cloning vector - HG14081-G from Sino Biological Species Human

Human BSCL2 ORF Clone (BC012140) - CDCS407722 from Creative biogene Species Human Accession Q96G97

Human BSCL2 ORF Clone (BC009866) - CDCS407723 from Creative biogene Species Human Accession Q96G97

Human BSCL2 ORF Clone (BC004911) - CDCS407724 from Creative biogene Species Human Accession Q96G97

Human BSCL2 ORF Clone (BC041640) - CDCS407725 from Creative biogene Species Human Accession Q96G97

Human BSCL2 ORF clone (BC009866) - CDCB159406 from Creative biogene Species Human

Human BSCL2 Gene ORF cDNA clone expression plasmid - HG14081-UT from Sino Biological Species Human

Human BSCL2 Gene ORF cDNA clone expression plasmid, C-Myc tag - HG14081-CM from Sino Biological Species Human

Human BSCL2 Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG14081-ACR from Sino Biological Species Human

Human BSCL2 Gene ORF cDNA clone expression plasmid, C-HA tag - HG14081-CY from Sino Biological Species Human

Human BSCL2 Gene ORF cDNA clone expression plasmid, N-HA tag - HG14081-NY from Sino Biological Species Human

Human BSCL2 Gene ORF cDNA clone expression plasmid, C-His tag - HG14081-CH from Sino Biological Species Human

Human BSCL2 Gene ORF cDNA clone expression plasmid, N-Flag tag - HG14081-NF from Sino Biological Species Human

Human BSCL2 Gene ORF cDNA clone expression plasmid, C-Flag tag - HG14081-CF from Sino Biological Species Human

Human BSCL2 Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG14081-ACG from Sino Biological Species Human

Human BSCL2 Gene ORF cDNA clone expression plasmid, N-Myc tag - HG14081-NM from Sino Biological Species Human

Human BSCL2 Gene ORF cDNA clone expression plasmid, N-His tag - HG14081-NH from Sino Biological Species Human

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