BSCL2

Gene Symbol BSCL2
Entrez Gene 26580
Alt Symbol GNG3LG, HMN5, PELD, SPG17
Species Human
Gene Type protein-coding
Description Berardinelli-Seip congenital lipodystrophy 2 (seipin)
Other Description Bernardinelli-Seip congenital lipodystrophy type 2 protein|seipin
Swissprots Q96G97 Q567S1 Q9BSQ0 Q96SV1 G3XAE4
Accessions ACA50720 CAF86927 CAI93437 EAW74070 EAW74071 EAW74072 EAW74073 EAW74074 EAW74075 EAW74076 EAW74077 EAW74078 EAW74080 EAW74081 Q96G97 AF052149 AK027524 BAB55175 AK075317 BAC11543 AK223606 BAD97326 AK225029 AK315423 BC004911 AAH04911 BC009866 BC012140 AAH12140 BC041640 AAH41640 BC093048 AAH93048 BG699373 BM763152 BP370169 CD107822 DB178846 DB296305 DQ575792 DQ584208 DQ893483 ABM84409 EU176769 ABW03570 NM_001122955 NP_001116427 NM_001130702 NP_001124174 NM_032667 NP_116056 NR_037948 NR_037949
Function Is a regulator of lipid catabolism essential for adipocyte differentiation. May also be involved in the central regulation of energy homeostasis (By similarity). Necessary for correct lipid storage and lipid droplets maintenance; may play a tissue-autonomous role in controlling lipid storage in adipocytes and in preventing ectopic lipid droplet formation in non-adipose tissues. {ECO:0000250, ECO:0000269|PubMed:19278620, ECO:0000269|PubMed:21533227}.
Subcellular Location Endoplasmic reticulum membrane {ECO:0000269|PubMed:14981520, ECO:0000269|PubMed:16574104, ECO:0000269|PubMed:18458148}; Multi-pass membrane protein {ECO:0000269|PubMed:14981520, ECO:0000269|PubMed:16574104, ECO:0000269|PubMed:18458148}.
Tissue Specificity Expressed in motor neurons in the spinal cord and cortical neurons in the frontal lobe (at protein level). Highly expressed in brain, testis and adipose tissue. {ECO:0000269|PubMed:11479539, ECO:0000269|PubMed:18458148, ECO:0000269|PubMed:18585921}.

Seipin CRISPR/Cas9 KO Plasmid (h) - sc-406865 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Seipin HDR Plasmid (h) - sc-406865-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Seipin Double Nickase Plasmid (h) - sc-406865-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Seipin Double Nickase Plasmid (h2) - sc-406865-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Seipin CRISPR Activation Plasmid (h) - sc-406865-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Seipin CRISPR Activation Plasmid (h2) - sc-406865-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Seipin Lentiviral Activation Particles (h) - sc-406865-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Seipin Lentiviral Activation Particles (h2) - sc-406865-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Seipin siRNA (h) - sc-62990 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Seipin shRNA Plasmid (h) - sc-62990-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Seipin shRNA (h) Lentiviral Particles - sc-62990-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Seipin/BSCL2 RNAi - H00026580-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

CompoZr® Knockout ZFN Kit - CKOZFN4076 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND4076 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

BSCL2 siRNA (Human) - CRH8866 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

BSCL2 - MBS8239816 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

Human BSCL2 siRNA - orb269368 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

BSCL2 shRNA Plasmid (Human) - CHH8866 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human
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