BSCL2

Gene Symbol	BSCL2
Entrez Gene	26580
Alt Symbol	GNG3LG, HMN5, PELD, SPG17
Species	Human
Gene Type	protein-coding
Description	Berardinelli-Seip congenital lipodystrophy 2 (seipin)
Other Description	Bernardinelli-Seip congenital lipodystrophy type 2 protein|seipin
Swissprots	Q96G97 Q567S1 Q9BSQ0 Q96SV1 G3XAE4
Accessions	ACA50720 CAF86927 CAI93437 EAW74070 EAW74071 EAW74072 EAW74073 EAW74074 EAW74075 EAW74076 EAW74077 EAW74078 EAW74080 EAW74081 Q96G97 AF052149 AK027524 BAB55175 AK075317 BAC11543 AK223606 BAD97326 AK225029 AK315423 BC004911 AAH04911 BC009866 BC012140 AAH12140 BC041640 AAH41640 BC093048 AAH93048 BG699373 BM763152 BP370169 CD107822 DB178846 DB296305 DQ575792 DQ584208 DQ893483 ABM84409 EU176769 ABW03570 NM_001122955 NP_001116427 NM_001130702 NP_001124174 NM_032667 NP_116056 NR_037948 NR_037949
Function	Is a regulator of lipid catabolism essential for adipocyte differentiation. May also be involved in the central regulation of energy homeostasis (By similarity). Necessary for correct lipid storage and lipid droplets maintenance; may play a tissue-autonomous role in controlling lipid storage in adipocytes and in preventing ectopic lipid droplet formation in non-adipose tissues. {ECO:0000250, ECO:0000269|PubMed:19278620, ECO:0000269|PubMed:21533227}.
Subcellular Location	Endoplasmic reticulum membrane {ECO:0000269|PubMed:14981520, ECO:0000269|PubMed:16574104, ECO:0000269|PubMed:18458148}; Multi-pass membrane protein {ECO:0000269|PubMed:14981520, ECO:0000269|PubMed:16574104, ECO:0000269|PubMed:18458148}.
Tissue Specificity	Expressed in motor neurons in the spinal cord and cortical neurons in the frontal lobe (at protein level). Highly expressed in brain, testis and adipose tissue. {ECO:0000269|PubMed:11479539, ECO:0000269|PubMed:18458148, ECO:0000269|PubMed:18585921}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human BSCL2 protein fragment - ab162019 from Abcam Category Protein Prices $402.00 Sizes 10 µg Source Wheat germ Species Human

Human BSCL2 protein fragment - ab162020 from Abcam Category Protein Prices $402.00 Sizes 10 µg Source Wheat germ Species Human

BSCL2 Antibody Blocking Peptide - LS-E52 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

BSCL2 Antibody Blocking Peptide - LS-E18097 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Seipin/BSCL2 Partial Recombinant Protein - H00026580-Q02 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human Seipin/BSCL2 Protein - H00026580-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

BSCL2-Antibody-N-term-Blocking-peptide - BP10112a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

BSCL2 Blocking Peptide - 33R-7521 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

Seipin / BSCL2 - H00026580-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

Seipin / BSCL2 - H00026580-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

Seipin / BSCL2 - H00026580-Q02 from Acris Antibodies Category Protein Prices $370.00 Sizes 10 µg Species Human

Seipin / BSCL2 - H00026580-Q02-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

Seipin / BSCL2 - H00026580-Q02-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

BSCL2 fusion protein - ag14149 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

BSCL2 fusion protein - Ag14953 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

Seipin - ABP-281-0150 from Nordic BioSite Category Protein Species Human

Seipin - ABP-281-011000 from Nordic BioSite Category Protein Species Human

Seipin - ABP-281-01100 from Nordic BioSite Category Protein Species Human

Seipin / BSCL2 (transcript variant 2) - TP303625 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

Seipin/BSCL2 Recombinant Protein Antigen - NBP1-81812PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

Seipin (BSCL2), Recombinant Protein - MBS7010480 from MyBioSource Category Protein Prices $1,205.00, $2,190.00, $3,395.00 Sizes 10 µg, 50 µg, 100 µg Source Cell Free Expression Species Human

BSCL2 fusion protein - Ag26811 from Proteintech Group Category Protein Source E. coli -derived, PET28a Species Human

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