Gene Symbol | SEC22B |
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Entrez Gene | 9554 |
Alt Symbol | ERS-24, SEC22L1 |
Species | Human |
Gene Type | protein-coding |
Description | SEC22 vesicle trafficking protein homolog B (S. cerevisiae) (gene/pseudogene) |
Other Description | ER-Golgi SNARE of 24 kDa|SEC22 vesicle trafficking protein-like 1|SEC22 vesicle-trafficking protein homolog B|vesicle-trafficking protein SEC22b |
Swissprots | A8K1G0 O75396 |
Accessions | O75396 AA135767 AF047442 AAC39893 AI085383 AK289875 BAF82564 BC001364 AAH01364 BU741516 CD619408 DQ892584 ABM83510 DQ895801 ABM86727 NM_004892 NP_004883 |
Function | SNARE involved in targeting and fusion of ER-derived transport vesicles with the Golgi complex as well as Golgi-derived retrograde transport vesicles with the ER. {ECO:0000269|PubMed:15272311}. |
Subcellular Location | Endoplasmic reticulum membrane {ECO:0000250}; Single-pass type IV membrane protein {ECO:0000250}. Endoplasmic reticulum-Golgi intermediate compartment membrane {ECO:0000250}. Golgi apparatus, cis-Golgi network membrane {ECO:0000250}. Golgi apparatus, trans-Golgi network membrane {ECO:0000250}. Melanosome {ECO:0000269|PubMed:17081065}. Note=Concentrated most in the intermediate compartment/cis-Golgi network and the cis-Golgi cisternae 1 and 2. Greatly reduced in concentration at the trans end of the Golgi apparatus. Identified by mass spectrometry in melanosome fractions from stage I to stage IV. |
Top Pathways | Phagosome, Legionellosis, SNARE interactions in vesicular transport |
SEC22B (29-F7) - sc-101267 from Santa Cruz Biotechnology
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SEC22B (K-13) - sc-165448 from Santa Cruz Biotechnology
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SEC22B (Q-12) - sc-165449 from Santa Cruz Biotechnology
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Anti-SEC22L1 antibody - ab72400 from Abcam
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Anti-SEC22L1 antibody - ab116676 from Abcam
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Anti-SEC22L1 antibody - ab56747 from Abcam
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Anti-SEC22L1 antibody [EPR12335] - ab181076 from Abcam
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Anti-SEC22B Antibody (aa2-50) - LS-C94813 from LifeSpan Bioscience
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Anti-SEC22B Antibody - LS-C94836 from LifeSpan Bioscience
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Anti-SEC22B Antibody (aa1-111, clone 10B2464, Azide-free) - LS-C183709 from LifeSpan Bioscience
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Anti-SEC22B Antibody (aa75-104, AP) - LS-C240509 from LifeSpan Bioscience
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Anti-SEC22B Antibody (aa75-104, APC) - LS-C240511 from LifeSpan Bioscience
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Anti-SEC22B Antibody (aa75-104, Biotin) - LS-C240512 from LifeSpan Bioscience
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Anti-SEC22B Antibody (aa75-104, FITC) - LS-C240513 from LifeSpan Bioscience
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Anti-SEC22B Antibody (aa75-104, PE) - LS-C240516 from LifeSpan Bioscience
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Anti-SEC22B Antibody (aa75-104, Azide-free, HRP) - LS-C248103 from LifeSpan Bioscience
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Anti-SEC22B Antibody (clone 5A10) - LS-C139362 from LifeSpan Bioscience
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Anti-SEC22B Antibody (aa75-104) - LS-C168929 from LifeSpan Bioscience
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SEC22B Antibody - NB100-91277 from Novus Biologicals
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SEC22B Antibody (1E1) - H00009554-M01 from Novus Biologicals
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SEC22B Antibody - NB100-98766 from Novus Biologicals
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SEC22B Antibody - NBP2-37701 from Novus Biologicals
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SEC22B Antibody (5A10) - H00009554-M03 from Novus Biologicals
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SEC22B Antibody - H00009554-A01 from Novus Biologicals
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Monoclonal Anti-SEC22L1 antibody produced in mouse - WH0009554M1 from Sigma-Aldrich
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