SEC22B

Gene Symbol SEC22B
Entrez Gene 9554
Alt Symbol ERS-24, SEC22L1
Species Human
Gene Type protein-coding
Description SEC22 vesicle trafficking protein homolog B (S. cerevisiae) (gene/pseudogene)
Other Description ER-Golgi SNARE of 24 kDa|SEC22 vesicle trafficking protein-like 1|SEC22 vesicle-trafficking protein homolog B|vesicle-trafficking protein SEC22b
Swissprots A8K1G0 O75396
Accessions O75396 AA135767 AF047442 AAC39893 AI085383 AK289875 BAF82564 BC001364 AAH01364 BU741516 CD619408 DQ892584 ABM83510 DQ895801 ABM86727 NM_004892 NP_004883
Function SNARE involved in targeting and fusion of ER-derived transport vesicles with the Golgi complex as well as Golgi-derived retrograde transport vesicles with the ER. {ECO:0000269|PubMed:15272311}.
Subcellular Location Endoplasmic reticulum membrane {ECO:0000250}; Single-pass type IV membrane protein {ECO:0000250}. Endoplasmic reticulum-Golgi intermediate compartment membrane {ECO:0000250}. Golgi apparatus, cis-Golgi network membrane {ECO:0000250}. Golgi apparatus, trans-Golgi network membrane {ECO:0000250}. Melanosome {ECO:0000269|PubMed:17081065}. Note=Concentrated most in the intermediate compartment/cis-Golgi network and the cis-Golgi cisternae 1 and 2. Greatly reduced in concentration at the trans end of the Golgi apparatus. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
Top Pathways Phagosome, Legionellosis, SNARE interactions in vesicular transport

SEC22B (29-F7) - sc-101267 from Santa Cruz Biotechnology

Prices $295.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal
SEC22B (29-F7): sc-101267. Western blot analysis of SEC22B expression in HeLa whole cell lysate.

SEC22B (K-13) - sc-165448 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

SEC22B (Q-12) - sc-165449 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-SEC22L1 antibody - ab72400 from Abcam

Host Sheep
Clonality Polyclonal

Anti-SEC22L1 antibody - ab116676 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-SEC22L1 antibody (ab116676) at 1/100 dilution + Hela cell line lysate at 35 µg

Anti-SEC22L1 antibody - ab56747 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-SEC22L1 antibody [EPR12335] - ab181076 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR12335
Anti-SEC22L1 antibody [EPR12335] (ab181076) at 1/2000 dilution + SH-SY5Y cell lysate at 20 µgSecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/1000 dilution

Anti-SEC22B Antibody (aa2-50) - LS-C94813 from LifeSpan Bioscience

Prices $325.00
Sizes 500 µg
Host Rabbit
Clonality Polyclonal

Anti-SEC22B Antibody - LS-C94836 from LifeSpan Bioscience

Prices $325.00
Sizes 500 µg
Host Sheep
Clonality Polyclonal

Anti-SEC22B Antibody (aa1-111, clone 10B2464, Azide-free) - LS-C183709 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal
Clone 10B2464

Anti-SEC22B Antibody (aa75-104, AP) - LS-C240509 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SEC22B Antibody (aa75-104, APC) - LS-C240511 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SEC22B Antibody (aa75-104, Biotin) - LS-C240512 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SEC22B Antibody (aa75-104, FITC) - LS-C240513 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SEC22B Antibody (aa75-104, PE) - LS-C240516 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SEC22B Antibody (aa75-104, Azide-free, HRP) - LS-C248103 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SEC22B Antibody (clone 5A10) - LS-C139362 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 5A10
SEC22B monoclonal antibody (M03), clone 5A10. Western blot of SEC22B expression in PC-12.

Anti-SEC22B Antibody (aa75-104) - LS-C168929 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
SEC22B Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human brain tissue followed by peroxidase-conjugated secondary antibody and DAB staining.

SEC22B Antibody - NB100-91277 from Novus Biologicals

Prices $299.00
Sizes 500 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemistry-Paraffin: SEC22B Antibody [NB100-91277] - IHC on rat spinal cord using Rabbit antibody to SEC22B at a concentration of 30 ug/ml. Pre-absorption of the antibody with the immunising peptide completely abolishes the immunostaining (not shown).

SEC22B Antibody (1E1) - H00009554-M01 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 1E1
Western Blot: SEC22B Antibody (1E1) [H00009554-M01] - SEC22L1 monoclonal antibody (M01), clone 1E1 Analysis of SEC22L1 expression in HeLa.

SEC22B Antibody - NB100-98766 from Novus Biologicals

Prices $299.00
Sizes 500 µg
Host Sheep
Clonality Polyclonal

SEC22B Antibody - NBP2-37701 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: SEC22B Antibody [NBP2-37701] - Whole cell lysate (50 ug) from HeLa, 293T, and Jurkat cells prepared using NETN lysis buffer.  Affinity purified rabbit anti-SEC22B antibody used for WB at 1 ug/ml.  Detection: Chemiluminescence with an exposure time of 30 seconds.

SEC22B Antibody (5A10) - H00009554-M03 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 5A10
Western Blot: SEC22B Antibody (5A10) [H00009554-M03] - Analysis of SEC22B expression in HeLa(Cat # L013V1).

SEC22B Antibody - H00009554-A01 from Novus Biologicals

Prices $269.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal

Monoclonal Anti-SEC22L1 antibody produced in mouse - WH0009554M1 from Sigma-Aldrich

Prices $347.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 1E1
<B>Immunoblotting</B><BR/>Monoclonal Anti-SEC22L1, <B>Cat. No. WH0009554M1</B> used at the antibody concentration: 1 ~ 5 μg/mL. Specific band of ~24.6 kDa using HeLa lysate.
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