Gene Symbol | SERPINF1 |
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Entrez Gene | 5176 |
Alt Symbol | EPC-1, OI12, OI6, PEDF, PIG35 |
Species | Human |
Gene Type | protein-coding |
Description | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 |
Other Description | cell proliferation-inducing gene 35 protein|pigment epithelium-derived factor|serine (or cysteine) proteinase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1|serpin F1 |
Swissprots | Q96R01 Q96CT1 P36955 Q2TU83 Q13236 Q9BWA4 F1T092 |
Accessions | AAA84914 EAW90577 P36955 AA351026 AA658568 AB593011 BAJ83966 AB593012 BAJ83967 AB593013 BAJ83968 AF400442 AAK92491 AK315344 AY513280 AAT08033 BC000522 AAH00522 BC013984 AAH13984 BM981180 BQ773314 BT007222 AAP35886 BU154385 CA405781 JF432524 ADZ15741 M76979 AAA60058 M90439 AAA93524 W22661 NM_002615 NP_002606 |
Function | Neurotrophic protein; induces extensive neuronal differentiation in retinoblastoma cells. Potent inhibitor of angiogenesis. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, it exhibits no serine protease inhibitory activity. {ECO:0000269|PubMed:7592790, ECO:0000269|PubMed:8226833}. |
Subcellular Location | Secreted {ECO:0000269|PubMed:17081065}. Melanosome {ECO:0000269|PubMed:17081065}. Note=Enriched in stage I melanosomes. |
Tissue Specificity | Retinal pigment epithelial cells and blood plasma. {ECO:0000269|PubMed:12737624}. |
Mouse SERPINF1 / PEDF ELISA Kit (Sandwich ELISA) - LS-F5976 from LifeSpan Bioscience
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Human SERPINF1 / PEDF ELISA Kit (Sandwich ELISA) - LS-F5793 from LifeSpan Bioscience
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Rat SERPINF1 / PEDF ELISA Kit (Sandwich ELISA) - LS-F8391 from LifeSpan Bioscience
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Bovine SERPINF1 / PEDF ELISA Kit (Sandwich ELISA) - LS-F8521 from LifeSpan Bioscience
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Mouse SERPINF1 / PEDF ELISA Kit (Sandwich ELISA) - LS-F12302 from LifeSpan Bioscience
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Human Serpin F1/PEDF DuoSet ELISA - DY1177-05 from R&D Systems
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Human Serpin F1 ELISA kit - orb196723 from Biorbyt
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Human PEDF ELISA Kit - abx054322 from Abbexa
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Human PEDF ELISA Kit - abx152695 from Abbexa
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Pigment Epithelium Derived Factor, PEDF, Human, ELISA Kit - E-EL-H1875 from ARP American Research Products
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Pigment Epithelium Derived Factor (PEDF), Human, ELISA Kit - SEB972Hu from ARP American Research Products
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Pigment epithelium-derived factor, PEDF, Human, ELISA Kit - CSB-E08818h from ARP American Research Products
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Pigment epithelium-derived factor, SERPINF1, Human, ELISA Kit - E0784h from ARP American Research Products
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Pigment Epithelium Derived Factor, PEDF, Mouse, ELISA Kit - E-EL-M0907 from ARP American Research Products
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Pigment Epithelium Derived Factor, PEDF, Rabbit, ELISA Kit - E-EL-RB1618 from ARP American Research Products
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Pigment Epithelium Derived Factor, PEDF, Chicken, ELISA Kit - E-EL-Ch0143 from ARP American Research Products
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Pigment Epithelium Derived Factor, PEDF, Porcine, ELISA Kit - E-EL-P0539 from ARP American Research Products
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Pigment Epithelium Derived Factor, PEDF, Sheep, ELISA Kit - E-EL-S0815 from ARP American Research Products
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Pigment Epithelium Derived Factor, PEDF, Guinea Pig, ELISA Kit - E-EL-GP0009 from ARP American Research Products
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Pigment Epithelium Derived Factor, PEDF, Monkey, ELISA Kit - E-EL-MK0656 from ARP American Research Products
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Pigment Epithelium Derived Factor (PEDF), Human, CLIA Kit - SCB972Hu from ARP American Research Products
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SERPINF1 (Human) Matched Antibody Pair - H00005176-AP31 from Acris Antibodies
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Human Serpin F1 ELISA - ELH-SerpinF1 from RayBiotech
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Human PEDF ELISA Kit - HP0091 from NeoScientific
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Anserine PEDF ELISA Kit - AP0091 from NeoScientific
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